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Neurology

Neuro Gait Analysis Study

TitleNeuro Gait Analysis Study
Contact Person Small Animal Neurology Service (979) 845-2351
Species Dogs
Inclusion Criteria and General Background Information

Monday – Thursday; 8a-5p ONLY

20 Dachshunds total

  • 10 Dachshunds with moderate SCIs- non-ambulatory paraparesis
  • MFS - 3
  • <7 day duration of clinical signs consistent with spinal cord injury
  • Lesion localized to T10-L2 intervertebral disc spaces
  • Advanced imaging and surgery to treat IVDH
  • 2-6 years of age
  • BCS <6 (0-9 scale)
  • 10 Dachshunds with severe SCIs – parapelegia
  • MFS – 0-2
  • <7 day duration of clinical signs consistent with spinal cord injury
  • Lesion localized to T10-L2 intervertebral disc spaces
  • Advanced imaging and surgery to treat IVDH
  • 2-6 years of age
  • BCS <6 (0-9 scale)

Kinetic/kinematic analysis:

  • Dogs with SCI (4 total): Days 3, 7, 30, 90
Exclusion Criteria
  • Disseminated neoplasia or systemic inflammation
  • History of recent breeding/pregnancy
  • Detectable orthopedic disease
  • Unsuitable temperament for repeated behavioral evaluation
Owner Commitments
Financial Incentives

$3750 package pricing

Effect of LUNAR-301 on Dogs with Glial Brain Tumors-Phase 1 Safety Study

TitleEffect of LUNAR-301 on Dogs with Glial Brain Tumors-Phase 1 Safety Study
Contact Person

Elizabeth Scanlin, BS

Cindy Schocke, CST

Beth Boudreau, DVM, PhD, DACVIM-Neurology

Species Dogs
Inclusion Criteria and General Background Information
  • Dogs at least one year of age
  • Diagnosed with a high-grade glioma
    • Presumptively (based on MRI characteristics) OR
    • Definitively (based on biopsy)
  • Normal organ and bonne marrow function
    • Determined by pre-treatment CBC/Chemistry/UA/Coag panel

MRI+/-biopsy and clinicopathological testing must be complete and reviewed before patient can be enrolled in the study

Exclusion Criteria
  • Dogs with severe signs of brain disease on the Modified Glasgow Coma Scale
    • MGCS<15
  • Dogs with no discrete mass identified on MRI
  • Dogs that previously received chemotherapy
    • Chemotherapy for unrelated tumors OK
    • Corticosteroids are OK
Owner Commitments

Each enrolled dog will participate for a total of 19 days of treatment. Dogs must remain hospitalized during the entire duration of the study. Further details on the study procedures can be obtained by contacting the Neurology Staff at 979-845-2351

Financial Incentives
  • Costs of hospitalization, drug administration and diagnostic monitoring between enrollment and completion of the study will be covered by the study
  • Costs of the brain biopsy (if elected by the owner) will be covered by the study
  • Up to $2,000 for the treatment of adverse events related to the study drug will be covered by the study