|Inclusion Criteria and General Background Information||
50 dogs are required to complete the study
・Dogs must be healthy and cooperative for physical exam.
・Dogs must be 6-10 years old, and 40-80 pounds in size.
・Dogs must be heartworm test negative and receiving consistent
・Medical history, physical examination and blood and urine tests
will be used to determine health status.
The study duration is one year, and all dogs will be enrolled in
College Station, Texas. Enrolled dogs will be randomized to receive
rapamycin or placebo for 6 months, and monitored for a year. Dogs
will be examined 4 times over the course of the year and owners
will complete health-related questionnaires at each study-related
visit and periodically throughout the year.
The costs of all four veterinary visits, including cardiac
examinations, diagnostic testing, and study drug, will be covered
by the study.