Phone: (979) 458-0128
My laboratory is interested in the role played by cytoskeletal remodeling in development and disease, particularly, angiogenesis and tumor progression and invasion. The long-term goal of our research is to understand how extracellular signals that alter tyrosine phosphorylation and the metabolism of inositol phospholipids modulate actin dynamics and cell motility. Areas of interest include the biogenesis of actin-based structures of invasion, intracellular trafficking, and three-dimensional tissue morphogenesis in vitro. Our research employs a combination of molecular genetics, cell biology, proteomics, and high-resolution optical imaging.
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