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Lab Activities

Janurary 2014

We started 2014 with new members and new awards!

Congratulations to Richard who secured a CVM Graduate Student Research Grant after a short period joining the lab! Keep up the curiosity-driven project!

Congratulations To Eddie, who is recognized by our College with a High-Impact Award in the Large Grant (for his AHA-predoctoral Award started from 2013 to 2015).

Congratulations to Shikhi that after graduation from TAMU expected in may, she will be a NIH-PostBac fellow to continue her exploration in hematopoiesis and transplantation!

Welcome our newest member Brenda, a freshman from Biology who will start her research journey for undergraduate research in our lab!

 

Nov. 2013

Cheers to Shikhi! She just received an Abstract Achievement Award from American Society of Hematology to present her first authored report on the Annual Conference in Dec at New Orleans. Her abstract tile is MiR-150 Inhibits MLL-AF9 Associated Leukemia By Suppressing Leukemic Stem Cells.

October. 2013

First thing first, Shikhi's abstract was accepted to present at 55th ASH conference. Congrats!

Next, we added new members: Haiqing, who  locks bikes close to hers! Hopefully, our newest member, Hui, will not do the same thing. Enjoy Aggieland.

Last month, our miR-223 story was selected by Editors of Circulation as one of the Top read articles in Molecular Cardiology.

Also, five members from our lab attended Whitehead Institute (@ WI/MIT) Colloqium. Everything was perfect, except it suppose to have six travellers...

 

Aug. 2013

*Welcome! Two new members just joined our team: Cheng-An "Richard" Change in July and Thomas Hunt in Aug.

* our article about miR-223 regulating macrophage polarization is higlighted in the Circulation Top Review series of "Circulation Editors' Picks: Most Read Articles on the Topic of Molecular Cardiology"  (Circulation. 2013;128:e88-e99)

* Our recent report on miR-150 suppressing MLL leukemia (MCR) was selected by Editors as the leading highlight in Aug issue of MCR, along with the introduction was our "leukemic cell" figure

June 2013

*Congratulations to Eddie Wei Ying who just received a pre-doctoral fellowship from American Heart Association (Southwest Region)!

* Eddie also won one of the two "the 5th CADA Research Award" in Chicago! Our trip to CADA and ADA conferences in Chicago is filled with fun.

* Our new article about miR-150 suppressing MLL leukemia (MCR, Epub) is feathered by MDLinx and LeadDiscovery, and selected as leading highlight article in MCR Aug issue.

 

March 2013

It is a wonderful March for the lab. We have several reasons to celebrate!

* First, Shikhi, Eddie and Sri, three members in our lab shared their exciting research with colleagues on campus during the SRW. Thank you all for your great talks!

*  Bonus! Eddie won the sencond place in oral presentations in Medical Scinece Category.

*  Third, a plaque for Outstanding Scientific Achievement is now in Beiyan'a office.

Cheers!

Nov. 2012

Congratulations to Eddie, who presented our very recent discovery on the Late Breaking Basic Science of Annual AHA conference.

August 2012

Congratulations to Cong, who is awarded "Outstanding Graduate Student Scholarship" from our college.

March 2012

Patali S Cheruku did an excellent plateform presentation in the Student Research Week symposium on the topic of the regulatory mechanim of microRNAs in early B cell development.  The graduate student Cong Meng is her mentor on this project.

Dec. 2011

A poster from our lab is presented at 53rd American Society of Hematology annual conference, San Diego, CA, 2011


MiR-150 Suppresses MLL-AF9 Associated Leukemia Through Simultaneously Targeting Multiple Oncogenes

Guoqing Zhuang*1, Marina Bousquet*2, Cong Meng*1,3 (equal contribution),  Andrew T Shie2,5, Jin Wang1, Stephanie Wang2, Guangtao Ge4, Piu Wong2, Gang Wang1, Lei Shi1,6, Patali Cheruku1, Beiyan Zhou1†

1 Department of Physiology and Pharmacology, College of Veterinary Medicine and Biological Sciences, Texas A&M University, College Station, TX, USA   77843; 2 Whitehead Institute for Biomedical Research, Cambridge, MA, USA  02142;  3 Department of Nutrition and Food Science , Texas A&M University, College Station, TX USA, 77843; 4 LeapFrogRx Inc, 1432 Main St. Waltham, MA 02415; 5 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA, 02138; 6 Department of Oncology, Renmin Hospital, Wuhan University, Wuhan, China

Nov. 2011

Nov. 4th

Guoqing Zhuang presented a poster about microRNA regulation in leukemic stem cells at the Stem Cell Symposium: Moving Adult Stem Cells and the Therapeutic Proteins they produce from the Laboratory to the Patient, College Station, TX

Nov 11-16

Guoqing, Cong and Lei attended 2011 American Heart Association Annual conference in Orlando, FL in Nov. They have contributed two poster presentations which are published online (Circulation for #1; Circulation Research for #2).

1. MicroRNA-223 Regulates Macrophage Polarization and Protects Mice from Diet-induced Insulin Resistance and Adipose Tissue Inflammation

Guoqing Zhuang1, Cong Meng2, Xin Guo2, Hang Xu2, Gang Wang1, Honggui Li2, Lei Shi1, 3, Chaodong Wu2†, Stephen Safe1 and Beiyan Zhou 1†


1 Department of Veterinary Physiology & Pharmacology, Texas A&M University, College Station, TX, USA; 2 Intercollegiate Faculty of Nutrition, Department of Nutrition and Food Science, Texas A&M University, College Station, TX, USA; 3 Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, P . R . China † Corresponding Author

2. A new page in the story of high-fat diet induced adipose tissue inflammation: A novel macrophage activation regulator, miR-223

Cong Meng1, 2*, Guoqing Zhuang1* (equal contribution) ,Xin Guo2, Hang Xu2, Gang Wang1, Honggui Li2, Lei Shi1, 3, Stephen Safe1, Beiyan Zhou 1†

1 Department of Veterinary Physiology & Pharmacology, Texas A&M University, College Station, TX, USA ; 2 Intercollegiate Faculty of Nutrition, Department of Nutrition and Food Science, Texas A&M University, College Station, TX, USA; 3 Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, P . R . China

 

Aug 2011

Guoqing Zhuang, Cong Meng and Lei Shi presented three posters about their research at the Toxicology Forum 2011, College Station, TX