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Joe Arosh

Professor

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Phone: (979) 845-6173

Mailstop: 4458

Department: VIBS

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Education

  • Ph.D. Reproductive Endocrinology, Laval University, Canada 0
  • M.V.Sc. Obstetrics & Gynecology, Madras Veterinary College, India 0
  • B.V.Sc. , Madras Veterinary College, India 0
  • , 0

Scholarly Interests

central role of prostaglandins on molecular and cellular aspects of reproductive processes, gynecologic diseases and endocrine cancers.

Publications

Prenatal exposure to chromium induces early reproductive senescence by increasing germ cell apoptosis and advancing germ cell cyst breakdown in the F1 offspring.
Sivakumar KK, Stanley JA, Arosh JA, Pepling ME, Burghardt RC, Banu SK.
Dev Biol. ; 388(1):22-34.
PPARγ activation inhibits growth and survival of human endometriotic cells by suppressing estrogen biosynthesis and PGE2 signaling.
Lebovic DI, Kavoussi SK, Lee J, Banu SK, Arosh JA.
Endocrinology. ; 154(12):4803-13.
Intrauterine inhibition of prostaglandin transporter protein blocks release of luteolytic PGF2alpha pulses without suppressing endometrial expression of estradiol or oxytocin receptor in ruminants.
Lee J, McCracken JA, Banu SK, Arosh JA.
Biol Reprod. ; 89(2):27.
Postnatal exposure to chromium through mother's milk accelerates follicular atresia in F1 offspring through increased oxidative stress and depletion of antioxidant enzymes.
Stanley JA, Sivakumar KK, Nithy TK, Arosh JA, Hoyer PB, Burghardt RC, Banu SK.
Free Radic Biol Med. ; 61C:179-196.
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits adhesion of human endometriotic epithelial and stromal cells through suppression of integrin-mediated mechanisms.
Lee J, Banu SK, Burghardt RC, Starzinski-Powitz A, Arosh JA.
Biol Reprod. ; 88(3):77.
Early pregnancy induced expression of prostaglandin E2 receptors EP2 and EP4 in the ovine endometrium and regulated by interferon tau through multiple cell signaling pathways.
Lee J, Banu SK, Nithy TK, Stanley JA, Arosh JA.
Mol Cell Endocrinol. ; 348(1):211-23.
Chromium-VI arrests cell cycle and decreases granulosa cell proliferation by down-regulating cyclin-dependent kinases (CDK) and cyclins and up-regulating CDK-inhibitors.
Stanley JA, Lee J, Nithy TK, Arosh JA, Burghardt RC, Banu SK.
Reprod Toxicol. ; 32(1):112-23.
Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53.
Banu SK, Stanley JA, Lee J, Stephen SD, Arosh JA, Hoyer PB, Burghardt RC.
Toxicol Appl Pharmacol. ; 251(3):253-66.
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits invasion of human immortalized endometriotic epithelial and stromal cells through suppression of metalloproteinases.
Lee J, Banu SK, Subbarao T, Starzinski-Powitz A, Arosh JA.
Mol Cell Endocrinol. ; 332(1-2):306-13.
Interferon tau regulates PGF2alpha release from the ovine endometrial epithelial cells via activation of novel JAK/EGFR/ERK/EGR-1 pathways.
Banu SK, Lee J, Stephen SD, Nithy TK, Arosh JA.
Mol Endocrinol. ; 24(12):2315-30.
Transport of prostaglandin F(2alpha) pulses from the uterus to the ovary at the time of luteolysis in ruminants is regulated by prostaglandin transporter-mediated mechanisms.
Lee J, McCracken JA, Banu SK, Rodriguez R, Nithy TK, Arosh JA.
Endocrinology. ; 151(7):3326-35.
Selective blockade of prostaglandin E2 receptors EP2 and EP4 signaling inhibits proliferation of human endometriotic epithelial cells and stromal cells through distinct cell cycle arrest.
Lee J, Banu SK, Rodriguez R, Starzinski-Powitz A, Arosh JA.
Fertil Steril. ; 93(8):2498-506.
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkappaB, and beta-catenin pathways and activation of intrinsic apoptotic mechanisms.
Banu SK, Lee J, Speights VO Jr, Starzinski-Powitz A, Arosh JA.
Mol Endocrinol. ; 23(8):1291-305.
Induction of peritoneal endometriosis in nude mice with use of human immortalized endometriosis epithelial and stromal cells: a potential experimental tool to study molecular pathogenesis of endometriosis in humans.
Banu SK, Starzinski-Powitz A, Speights VO, Burghardt RC, Arosh JA.
Fertil Steril. ; 91(5 Suppl):2199-209.
Cyclooxygenase-2 regulates survival, migration, and invasion of human endometriotic cells through multiple mechanisms.
Banu SK, Lee J, Speights VO Jr, Starzinski-Powitz A, Arosh JA.
Endocrinology. ; 149(3):1180-9.
Gene expression profiles and functional characterization of human immortalized endometriotic epithelial and stromal cells.
Banu SK, Lee J, Starzinski-Powitz A, Arosh JA.
Fertil Steril. ; 90(4):972-87.
Molecular cloning and characterization of prostaglandin (PG) transporter in ovine endometrium: role for multiple cell signaling pathways in transport of PGF2alpha.
Banu SK, Lee J, Satterfield MC, Spencer TE, Bazer FW, Arosh JA.
Endocrinology. ; 149(1):219-31.


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