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Age Matters for Genes in Evolution

Posted November 15, 2011

Our new study published in the Genome Biology and Evolution shows that evolutionary age of protein-coding genes in human and chimp determines the rate of mutation accumulation, as well as the fitness effect of mutations. Collectively our results provide strong evidence that younger genes are subject to weaker purifying selection and more tenuous evidence that they also undergo adaptive evolution more frequently. For details visit http://gbe.oxfordjournals.org/cgi/content/abstract/evq019.



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