Skip Navigation

Molecular Cytogenetics and Genomics Laboratory

Recent Publications

2012

Avila, F., Das, P.J., Kutzler, M., Owens, E., Perelman, P., Rubes, J., Johnson, W.E. and Raudsepp.T. 2012. Development and application of molecular tools for camelid cytogenetics. The Journal of Heredity (special issue for camelid genetics; accepted for publication).

Avila, F., Das, P.J., Kutzler, M.A., Owens, E., Perelman, P., Raudsepp, T. 2012. Development and application of molecular tools for camelid cytogenetics. Cytogenetics and Genome Research 136:314-359(11).

Das, P.J., Mishra, D. K., Avila, F., Johnson, G., Chowdhary, B. P., Raudsepp, T. 2012. Identification and expression analysis of the pig pseudoautosomal region using molecular cytogenetics approach. Cytogenet Genome Res 136:314-359(13).

Ferrer, M., Anderson, D., Jones, M., Raudsepp, T., Avila, F., Miesner, M., DeBey, B., Kutzler, M. 2012. Segmental aplasia of the right uterine horn with mucometra in an alpaca. JAVMA 241(6):697-700.

Janečka JE, Chowdhary B, Murphy WJ. 2012. Exploring the correlations between sequence evolution rate and phenotypic divergence across the Mammalian tree provides insights into adaptive evolution. Journal of Bioscience 37:1-13.

Janečka JE. 2012. Tracks of my soul. In: Snow Leopard Stories from the Roof of the World. Don Hunter, Editor. University Colorado Press. Pp. 25-31

Holbrook JD, De Young RW, Janečka JE, Tewes ME, Honeycutt RL, Young JH. 2012. Genetic diversity, population structure, and movements of mountain lions (Puma concolor) in Texas. Journal of Mammalogy 93:989-1000.

Murphy MJ, Janečka JE, Stadler T, Eizirik E, Ryder OA, Gatesy J, Meredith RW, Springer MS. 2012. Response to Comment on "Impacts of the Cretaceous Terrestrial Revolution and KPg Extinction on Mammal Diversification". Science 337:34-35.

Raudsepp T, Das PJ, Avila F, Chowdhary BP. 2012. The pseudoautosomal region and sex chromosome aneuploidies in domestic species. Sex Development 6(1-3):72-83.

Rodgers T, JanečkaJE. 2012. Applications and techniques for non-invasive faecal genetics research in felid conservation. European Journal of Wildlife Research DOI: 10.1007/s10344-012-0675-6.

Rosen T, Hussain S, Mohammad G, Jackson R, Janečka JE, Michel S. 2012. Reconciling sustainable development of mountain communities with large carnivore conservation. Mountain Research and Development 32:286-293.

Springer MS, Meredith R, Gatesy J,  Emerling C,  Park J, Rabosky D, Stadler TC, Ryder O, JanečkaJE, Fisher C, Murphy W. 2012. Macroevolutionary dynamics and historical biogeography of primate diversification inferred from a species supermatrix. PLoS ONE 7:11:e49521:1-23.

Steelman SM, Chowdhary BP.  2012. Plasma proteomics shows an elevation of the anti-inflammatory protein APOA-IV in chronic equine laminitis. BMC Vet Res. 8(179).

Steelman S, Chowdhary B, Suchodolski J, Dowd S, JanečkaJE. 2012. Pyrosequencing of 16s rRNA Genes in fecal samples reveals high diversity of hindgut microflora in horses and potential links to chronic laminitis. BMC Veterinary Research 8:231. DOI: 10.1186/1746-6148-8-231

2011

Anwar MB, Jackson R, Nadeem MS, Janecka JE, S Hussain, Beg MA, Ghulam M, and Qayyum M (2011) Food habits of snow leopard Panthera uncia (Schreber, 1775) in Baltistan, Northern Pakistan. European Journal of Wildlife Research. 57:1077-1083.

Durkin K, Raudsepp T and Chowdhary BP (2011) Cytogenetic Evaluation of the Stallion. In Equine Reproduction. (Eds. A.O. McKinnon, E.L. Squires, W.E. Vaala and D.D. Varner), Wiley Blackwell, Ch. 306.

Gilad O, Janecka, JE, Armstrong F, Tewes ME, Honeycutt TL (2011) Mountain lions in Guadalupe Mountains National Park: Estimates of occurrence and distribution through DNA analysis. Southwestern Association of Naturalists. 56:297-304.

Janecka JE, Munkhtsog B, Jackson RM, Mallon DP, Naranbaatar G, Gerelmaa K, Murphy WJ (2011) Comparison of noninvasive genetic and camera-trapping techniques for surveying snow leopards. Journal of Mammalogy.92:771-783.

Janečka JE, Tewes ME, Laack LL, Caso A, Grassman LI Jr, Haines AM, Shindle D, Davis B, Murphy WJ, Honeycutt RL (2011) Reduced genetic diversity and isolation of remnant ocelot populations occupying a severely fragmented landscape in southern Texas. Animal Conservation. 14:608-619.

Kachroo, P., Ivanov, I., Davidson, L.A., Chowdhary, B.P., Lupton, J.R., Chapkin, R.S. 2011. Classification of Diet-Modulated Gene Signatures at the Colon Cancer Initiation and Progression Stages. Digestive Diseases and Sciences. 9:2595-604.

Li G, Janecka JE, Murphy WJ (2011) Accelerated evolution of a putative premating isolation gene, CES7, in the cat family. Molecular Biology and Evolution. 28:911-920.

*Meredith, RW, *Janečka JE, Gatesy J, Ryder OA, Fisher CA, Teeling EC, Alisha Goodbla A, Eizirik E, Simão TLL, Stadler T, Rabosky DL, Honeycutt RL, Flynn JF, Ingram CI, Steiner C, Williams TL, Robinson TJR, Burk-Herrick A, Westerman M, Ayoub NA, *Springer MS, *Murphy WJ (2011) Impacts of the Cretaceous Terrestrial Revolution and KPg Extinction on Extant Mammal Diversification. Science 334:521-524.*These authros contributed equally.

Paria, N.*, Raudsepp, T* ., Wilkerson, A.J., O'Brien, P.C.M., Ferguson-Smith, M.A., Love, C.C., Arnold, C., Rakestraw, P., Murphy, W.J., Chowdhary, B.P. (2011) A gene catalogue of the euchromatic male specific region of the horse Y chromosome: Comparison with human and other mammals. PLoS ONE 6(7):e212374: 1-13. *These authors have equal contribution

Raudsepp, T. and Chowdhary, B.P. 2011. Cytogenetics and physical chromosome maps. Chpt. 7. In: The Genetics of the Pig (Eds. A. Ruvinsky and M. Rothschild), CAB International, pp. 134-78.

Springer MS, Meredith RW, Janecka JE, Murphy WJ (2011) The historical biogeography of Mammalia. Jones KE and Safi K (eds) Global Biodiversity of Mammals: Past, Present and Future. Philosophical Transactions of the Royal Society B: Biological Sciences (Invited Paper for Special Issue). 366:2478-2502.

2010

Das, P.J., Paria, N., Gustafson-Seabury, A., Vishnoi, M., Chaki, S., Love, C.C., Varner, D.D., Chowdhary, B.P., Raudsepp, T. 2010. Total RNA isolation from stallion sperm and testis biopsies. Theriogenology, 74, 1099-1106

Das, P.J., Vishnoi, M., Kachroo, P., Wang, J., Love, C.C., Varner, D.D., Chowdhary, B.P., Raudsepp, T. 2010. Expression microarray profiling of sperm and testis mRNA of reproductively normal stallions. Animal Reproduction Science, 121S, S175.

Juras R., Raudsepp T., Das P.J., Conant E., Cothran E.G. 2010. XX/XY blood lymphocyte chimerism in heterosexual dizygotic American Bashkir Curly horse twins. J Equine Vet Sci 30, 575-580.

Raudsepp, T. , Durkin, K., Lear, T., Das, P.J., Avila, F. Kachroo, P., Chowdhary, B.P. 2010. Molecular heterogeneity of XY sex reversal in the horse. Animal Genetics 41 (Suppl. 2), 41-52 (Special Issue on Horse Genetics and Genomics).

Sudderth, A.K., Das, P.J., Varner, D.D., T. Raudsepp, T. 2010. Determination of optimal semen processing methods for total RNA isolation and sperm genomic analysis. Animal Reproduction Science, 121S, S149-S150.

2009

Alizadeh, A., Hong, L.Z, Kaelin, C.B, Raudsepp, T, Manuel, H and Barsh, G.S. 2009. Genetics of Sex-linked yellow in the Syrian hamster. Genetics, 181(4):1427-1436.

Brinkmeyer-Langford, CL, Childers C. Fritz K. Gustafson- Seabury A. Cothran M. Raudsepp, T. Womack, JE and Skow, LC. 2009. A High Resolution RH Map of the Bovine Major Histocompatibility Complex. BMC Genomics, 10:182-191.

Bright LA, Burgess SC, Chowdhary BP, Swiderski CE, McCarthy FM. Structural and functional-annotation of an equine whole genome oligoarray. BMC Bioinformatics 2009;10: 1-8.

Das, P.J., Chowdhary, B.P., Raudsepp, T. 2009. Characterization of the bovine pseudoautosomal region (PAR) and comparison with sheep, goat and other mammalian PARs. Cytogenet. Genome Res., 126, 139-147.

Davis BW, Raudsepp T, Pearks Wilkerson AJ, Agarwala R, Schäffer AA, Houck M, Ryder OA, Chowdhdary BP, Murphy WJ. 2009. A high-resolution cat radiation hybrid and integrated FISH mapping resource for phylogenomic studies across Felidae. Genomics, 93:299-304.

Di Meo GP, Perucatti A, Peretti V, Incarnato D, Ciotola F, Liotta L, Raudsepp T, Di Berardino D, Chowdhary B, Iannuzzi L. 2009. The 450-band resolution G- and R-banded standard karyotype of the donkey (Equus asinus, 2n = 62). Cytogenet Genome Res. 125: 266-271.

Liu J, Westhusin M, Johnson G, Raudsepp T, Chowdhary B, Burghardt R, Long C, Kraemer D. 2009. Evaluation of culture systems for attachment and proliferation of the epithelial cells cultured from ovine semen. Anim Reprod Sci. 115: 49-57.

Miller W, Drautz DI, Janecka JE, Lesk AM, Ratan A, Tomsho LP, Packard M, Zhang Y, McClellan LR, Qi J, Zhao F, Gilbert MTP, Dalén L, Arsuaga JL, Ericson PGP, Huson DH, Helgen KM, Murphy WJ, Götherström A, Schuster SC (2009) The mitochondrial genome sequence of the Tasmanian tiger (Thylacinus cynocephalus). Genome Research 19:213-220. Received JOURNAL COVER.

Schneider, D.A, Tibary, A., Raudsepp, T., Das, P.J., O'Rourke, K.I. 2009. Blood chimerism confounds genetic relative susceptibility testing for classical scrapie in sheep. J.Vet. Diagnostic Investigation, 21:295-305.

Shields, J.E., K.J. Kochan, K.J., Jeong, J., Abbey, C.A., Raudsepp, T., Riggs, P.K. 2009. Initial characterization of a gene abundantly expressed in stallion testis. J. Equine Vet. Sci., 29, 324-325

Wade CM, Giulotto E, Sigurdsson S, Zoli M, Gnerre S, Imsland F, Lear TL, Adelson DL, Bailey E, Bellone RR, Blöcker H, Distl O, Edgar RC, Garber M, Leeb T, Mauceli E, MacLeod JN, Penedo MCT, Raison JM, Sharpe T, Vogel J, Andersson L, Antczak DF, Biagi T, Binns MM, Chowdhary BP, Coleman SJ, Della Valle G, Fryc S, Guérin G, Hasegawa T, Hill EW, Jurka J, Kiialainen A, Lindgren G, Liu J, Magnani E, Mickelson JR, Murray J, Nergadze SG, Onofrio R, Pedroni S, Piras MF, Raudsepp T, Rocchi M, Røed KH, Ryder OA, Searle S, Skow L, Swinburne JE, Syvänen AC, Tozaki T, Valberg SJ, Vaudin M, White JR, Zody MC, Broad Institute Genome Sequencing Platfor, Broad Institute Whole Genome Assembly Team, Lander ES, and Lindblad-Toh K. 2009. Genome sequence, comparative analysis and population genetics of the domestic horse (Equus caballus). Science 326 (5954): 865-867.

2008

Brinkmeyer-Langford C, Raudsepp T, Gustafson-Seabury A, Chowdhary BP. 2008. A BAC contig map over the proximal approximately 3.3 Mb region of horse chromosome 21. Cytogenet. Genome Res. 120:164-172.

Chowdhary, B.P., Paria, N.P., Raudsepp, T. 2008. Potential applications of equine genomics in dissecting diseases and fertility. Animal Reproduction Science, 107, 208-218.

Chowdhary BP, Raudsepp T. 2008. The Horse Genome Derby: racing from map to whole genome sequence. Chromosome Res. 16, 109-127.

Janecka JE, Tewes ME, Laack LL, Grassman LI Jr, Haines AM, Honeycutt RL (2008) Small effective population sizes of two remnant ocelot populations (Leopardus pardalis albescens) in the United States. Conservation Genetics 9:869-878.

Janecka JE, Miller KM, Lim NT-L, Baba M, Izawa M, Boeadi, Murphy WJ (2008) Evidence for multiple species of Sunda colugos. Current Biology 18:R1001-R1002.

Janecka JE, Jackson R, Zhang Y, Li D, Munkhtsog B, Buckley-Beason V, Murphy WJ (2008) Population monitoring of snow leopards using noninvasive collection of scat samples: A pilot study. Animal Conservation 11:401-411. Received JOURNAL COVER.

Pearks-Wilkerson, A.J., Raudsepp, T., Graves, T., Warren, W., Chowdhary, B.P., Skow, L.C., Murphy, W.J. 2008. Physical mapping, gene discovery, and comparative analysis of X-degenerate genes from the domestic cat Y chromosome. Genomics, 92: 329-338.

Raudsepp, T. and Chowdhary, B.P. 2008. FISH for mapping single copy genes. In: Phylogenomics: Methods in Molecular Biology (Ed. W. Murphy), Humana Press, New Jersey, USA, pp.31-49.

Raudsepp, T. and Chowdhary, B. P. 2008. The horse pseudoautosomal region (PAR): characterization and comparison with the human, chimp and mouse PARs. Cytogenet. Genome Res. 121, 102-109.

Raudsepp, T., Gustafson-Seabury, A., Durkin, K., Wagner, M.L., Goh, G., Seabury, C.M., Brinkmeyer-Langford, C., Lee, E.-J., Agarwala, R., Stallknecht Rice, E., Schäffer, A.A., Skow, L.C., Tozaki, T., Yasue, H., M. Penedo, C.M., Lyons, L.A., Khazanehdari, K.A., Binns, M.M., MacLeod, J.N., Distl, O., Guérin, G., Leeb, T., Mickelson, J.R., Chowdhary, B.P. 2008. A 4103 marker integrated physical and comparative map of the horse genome, Cytogenet. Genome Res., 122, 28-36.

2007

Chiang, H.-I., Zhou, H., Raudsepp, T., Jesudhasan, P.R., Zhu, J.J. 2007. Chicken CD69 and CD94/NKG2-like genes in a chromosomal region syntenic to mammalian natural killer gene complex. Immunogenetics 59, 603-611.

Coleman SJ, Gong G, Gaile DP, Chowdhary BP, Bailey E, Liu L, MacLeod JN (2007) Evaluation of Compass as a comparative mapping tool for ESTs using horse radiation hybrid maps. Anim Genet 38:294-302

Goh, G*, Raudsepp, T*, Durkin, K, Wagner, ML, Schäffer, AA, Agarwala, R, Tozaki, T, Mickelson, JR and Chowdhary, BP. 2007. High-resolution gene maps of horse chromosomes 14 and 21: additional insights into evolution and rearrangements of HSA5 homologues in mammals. Genomics 89:89-112. Received JOURNAL COVER, *equal contribution.

Hansen GR, Abbey CA, Gaile DP, Raudsepp T, Chowdhary BP, Womack JE, Gill CA. 2007. Assignment of six genes to bovine chromosomes 5 and 16 by fluorescence in situ hybridization, radiation hybrid mapping and genetic linkage analysis. Cytogenet. Genome Res. 116: 194-197.

Herszberg B, Mata X, Giulotto E, Decaunes P, Piras FM, Chowdhary BP, Chaffaux S, Guerin G (2007) Characterization of the equine glycogen debranching enzyme gene (AGL): Genomic and cDNA structure, localization, polymorphism and expression. Gene 404:1-9

Janecka JE, Walker CW, Tewes ME, Caso A, Laack LL, Honeycutt RL (2007) Phylogenetic relationships of ocelot (Leopardus paradalis albescens) populations from the Tamaulipan Biotic Province and implications for recovery. Southwestern Naturalist 52:89-96. Received JOURNAL COVER.

Janecka JE, Miller W, Pringle TH, Wiens F, Zitzmann A, Helgen KM, Springer MS, Murphy WJ (2007) Molecular and genomic data identify the closest living relative of primates. Science 318:792-795.

Janecka JE, Grassman LI Jr, Honeycutt RL, Tewes ME (2007) Whole genome amplification for sequencing and applications in conservation genetics. The Journal of Wildlife Management 71:1357-1360.

Janecka JE, Blankenship TL, Hirth DH, Kilpatrick CW, Tewes ME, Grassman LI Jr (2007) Evidence for male-biased dispersal in bobcats Lynx rufus using relatedness analysis. Wildlife Biology 13:38-47.

Momozawa, Y., Takeuchi, Y.,Tozaki, T., Kikusui, T.,Hasegawa, T., Raudsepp, T., Chowdhary, B.P., Kusunose, R. and Mori, Y. 2007. SNP detection and radiation hybrid mapping horses of nine candidate genes for temperament. Animal Genetics, 38, 81-91.

Prause A, Guionaud CT, Klukowska-Rotzler J, Giulotto E, Magnani E, Chowdhary BP, Philipp U, Leeb T, Mevissen M (2007) Chromosomal assignment of five equine HTR genes by FISH and RH mapping. Anim Genet 38:83-4.

Stübs D, Kuiper H, Mömke S, Chowdhary BP, Distl O (2007) Assignment of the TYK2 gene to equine chromosome 7q12-q13. Archiv für Tierzucht 50:322-323.