The GI Lab at Texas A&M University provides specialized
testing services to help veterinarians diagnose and treat
gastrointestinal diseases in dogs and cats.
These tests may help in the management of pets with vomiting,
weight loss, diarrhea, loss of appetite, or poor body
All samples must be submitted by a veterinarian. Veterinary
specialists in Internal Medicine certified by the American College
of Veterinary Internal Medicine are available for consultation to
discuss interpretation of test results with submitting
veterinarians, and their implications for patient management.
We cannot give advice directly to pet owners due to licensure
Confused about Lipase Assays? Recently, questions have
been asked regarding various lipase testing methods for
The measurement of pancreatic lipase immunoreactivity (PLI; as
measured by Spec cPL® in dogs and Spec fPL®
in cats) has become the standard for the diagnosis of acute and
chronic pancreatitis in either species. While no diagnostic test is
100% sensitive and specific, these assays have been repeatedly
shown to be far superior to the measurement of serum lipase
activity. Recently, catalytic assays for the measurement of serum
lipase activity have been marketed with claims of comparable
diagnostic utility to the measurement of serum PLI concentrations.
While these assays utilize substrates other than the traditional
1,2 diglyceride (i.e., triolein in the case of v-Lip-P and DGGR in
the case of PrecisionPSLTM Pancreatic Sensitive Lipase
and several others), none of these other substrates are entirely
specific for the measurement of pancreatic lipase and consequently
they may detect other lipases that do not originate from the
exocrine pancreas. Therefore, the only assays that are specific for
the measurement of pancreatic lipase remain Spec cPL and Spec fPL.
Please let us know if you have any questions regarding lipase