Texas A&M Center Secures Funding To Continue Tissue Chip Testing And Promotion
Posted October 22, 2018
Following the completion of their first two years
of comprehensive, independent testing of 11 tissue chips,
researchers in the Tissue Chip Validation Center at Texas A&M
University (TEX-VAL) have been successful in securing a competitive
renewal award from the National Institutes of Health (NIH).
The competitive, multi-million-dollar grant from the NIH’s
National Center for Advancing Translational Sciences (NCATS) will
facilitate the creation of a public-private partnership that builds
on the existing infrastructure and expertise of TEX-VAL and
promotes the use of tissue chips by industry and regulatory bodies.
The center also will continue their work to validate the tissue
chip technology developed by their partners at a number of public
and private academic centers in the United States.
Led by College of Veterinary Medicine & Biomedical Sciences
(CVM) professor Ivan Rusyn, the TEX-VAL Center will work with key
members of the Innovation and Quality, or iQ, Consortium,
comprising toxicologists from pharmaceutical companies that are
interested in exploring the use of tissue chips for drug testing
The TEX-VAL Center has secured commitments to test 19 new tissue
chips from NIH-funded developers, as well as an interest in
discussing the consortium framework from key members of the iQ
Consortium and governmental agencies.
“We have already been successful in building close partnerships
with the academic laboratories that develop tissue chip technology.
I am delighted that our center brings value to our partners and
that they are happy to continue working with us,” Rusyn said. “The
major focus for this second, two-year grant is to engage even more
closely with companies, as a group or individually, and government
agencies to build a consortium that becomes a place where people
can discuss their experiences with the technology, but also can
actually do new testing and then share this information with
A tissue chip (courtesy of NCATS)
The ultimate goal is to establish a public-private partnership
that will transform the TEX-VAL Center into a self-sustaining
public-private consortium for tissue chip validation.
“As happens with many novel and complex technologies, industry
and regulatory agencies have been slow to adopt tissue chips
because of a lack of confidence in the reliability and relevance,”
Rusyn added. “The consortium will work to encourage tissue chip
adoption and serve as a practical pathway to what we hope will be
the eventual replacement of animal testing in the future.”
Other TEX-VAL Center investigators are: Weihsueh Chiu at the
CVM; Clifford Stephan at the Texas A&M Institute of Biosciences
and Technology; Terry Wade with the Texas A&M Geosciences and
Environmental Research Group; and Arum Han at the Texas A&M
College of Engineering.
Additional information on the award (U24 TR002633) is available
via the NIH Project Reporter, at
For more information about the Texas
A&M College of Veterinary Medicine & Biomedical Sciences,
please visit our website at vetmed.tamu.edu or join us on Facebook, Instagram, and Twitter.
Contact Information: Megan Palsa, Executive Director of
Communications, Media & Public Relations, Texas A&M College
of Veterinary Medicine & Biomedical Science; email@example.com;
979-862-4216; 979-421-3121 (cell)
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