Skip Navigation

Candice Brinkmeyer-Langford

Research Assistant Professor

Curriculum Vitae

Send Email

Phone: (979) 845-6780

Mailstop: 4458

Department: VIBS

Photo of Brinkmeyer-Langford, Candice

Education

  • Ph.D. Genetics, Texas A&M University 2006

Scholarly Interests

My primary research focus is genomics. I am particularly interested in comparative genomics: learning about the dynamics underlying human diseases by studying their counterparts in animals. One of the goals of my research is to identify and characterize environmental and genetic interactions that contribute to neurological conditions resulting from antecedent viral infections. I am particularly interested in identifying how genetic background influences disease diversity following infection by a neurotropic virus. This research is expected to increase knowledge about virally-influenced complex neurological conditions in humans and ultimately lead to the development of novel predictive models. I am also involved in research using a model of the human disease Duchenne muscular dystrophy known as Golden Retriever muscular dystrophy (GRMD). In both humans and dogs, this disease is caused by a genetic defect in a single gene, yet the amount of variation seen in the clinical signs of the disease suggests that other elements contribute to its presentation, progression, and overall severity. I seek to understand these modifying factors in GRMD, knowing that the findings can be used in the future to develop targeted treatments for the human disease.

Publications

A BAC contig map over the proximal approximately 3.3 Mb region of horse chromosome 21.
Brinkmeyer-Langford C, Raudsepp T, Gustafson-Seabury A, Chowdhary BP..
Cytogenet Genome Res.. ; 120(1-2):164-72.
Exceptional conservation of horse-human gene order on X chromosome revealed by high-resolution radiation hybrid mapping.
Raudsepp T, Lee EJ, Kata SR, Brinkmeyer C, Mickelson JR, Skow LC, Womack JE, Chowdhary BP..
Proc Natl Acad Sci U S A.. ; 101(8):2386-91..
A conserved segmental duplication within ELA.
Brinkmeyer-Langford CL, Murphy WJ, Childers CP, Skow LC.
Anim Genet. ; 41 Suppl 2:186-95.
A 1.3-Mb interval map of equine homologs of HSA2.
Wagner ML, Raudsepp T, Goh G, Agarwala R, Schaffer AA, Dranchak PK, Brinkmeyer-Langford C, Skow LC, Chowdhary BP, Mickelson JR.
Cytogenet Genome Res.. ; 112(3-4):227-34.
Aberrant gene expression in humans.
Zeng Y, Wang G, Yang E, Ji G, Brinkmeyer-Langford CL, Cai JJ.
PLoS Genet. ; 11(1):e1004942.
Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trials.
Kornegay JN, Spurney CF, Nghiem PP, Brinkmeyer-Langford CL, Hoffman EP, Nagaraju K.
ILAR J. ; 55(1):119-49.
Genetic risk factors for insidious equine recurrent uveitis in Appaloosa horses.
Fritz KL, Kaese HJ, Valberg SJ, Hendrickson JA, Rendahl AK, Bellone RR, Dynes KM, Wagner ML, Lucio MA, Cuomo FM, Brinkmeyer-Langford CL, Skow LC, Mickelson JR, Rutherford MS, McCue ME.
Anim Genet. ; 45(3):392-9.
Additive, epistatic, and environmental effects through the lens of expression variability QTL in a twin cohort.
Wang G, Yang E, Brinkmeyer-Langford CL, Cai JJ.
Genetics. ; 196(2):413-25.
Consequences of perinatal bisphenol A exposure in a mouse model of multiple sclerosis.
Brinkmeyer-Langford C, Rodrigues A, Kochan KJ, Haney R, Rassu F, Steelman AJ, Young C, Riggs P, Storts R, Meagher MW, Welsh CJ.
Autoimmunity. ; 47(1):57-66.
A high resolution RH map of the bovine major histocompatibility complex.
Brinkmeyer-Langford CL, Childers CP, Fritz KL, Gustafson-Seabury AL, Cothran M, Raudsepp T, Womack JE, Skow LC.
BMC Genomics. ; 10:182.
A 4,103 marker integrated physical and comparative map of the horse genome.
Raudsepp T, Gustafson-Seabury A, Durkin K, Wagner ML, Goh G, Seabury CM, Brinkmeyer-Langford C, Lee EJ, Agarwala R, Stallknecht-Rice E, Schäffer AA, Skow LC, Tozaki T, Yasue H, Penedo MC, Lyons LA, Khazanehdari KA, Binns MM, MacLeod JN, Distl O, Guérin G, Leeb T, Mickelson JR, Chowdhary BP.
Cytogenet Genome Res. ; 122(1):28-36.
A 1.3-Mb interval map of equine homologs of HSA2.
Wagner ML, Raudsepp T, Goh G, Agarwala R, Schaffer AA, Dranchak PK, Brinkmeyer-Langford C, Skow LC, Chowdhary BP, Mickelson JR.
Cytogenet Genome Res. ; 112(3-4):227-34.
The genome sequence of taurine cattle: a window to ruminant biology and evolution.
Bovine Genome Sequencing and Analysis Consortium, Elsik CG, Tellam RL, Worley KC, Gibbs RA, Muzny DM, Weinstock GM, Adelson DL, Eichler EE, Elnitski L, Guigó R, Hamernik DL, Kappes SM, Lewin HA, Lynn DJ, Nicholas FW, Reymond A, Rijnkels M, Skow LC, Zdobnov EM, Schook L, Womack J, Alioto T, Antonarakis SE, Astashyn A, Chapple CE, Chen HC, Chrast J, Câmara F, Ermolaeva O, Henrichsen CN, Hlavina W, Kapustin Y, Kiryutin B, Kitts P, Kokocinski F, Landrum M, Maglott D, Pruitt K, Sapojnikov V, Searle SM, Solovyev V, Souvorov A, Ucla C, Wyss C, Anzola JM, Gerlach D, Elhaik E, Graur D, Reese JT, Edgar RC, McEwan JC, Payne GM, Raison JM, Junier T, Kriventseva EV, Eyras E, Plass M, Donthu R, Larkin DM, Reecy J, Yang MQ, Chen L, Cheng Z, Chitko-McKown CG, Liu GE, Matukumalli LK, Song J, Zhu B, Bradley DG, Brinkman FS, Lau LP, Whiteside MD, Walker A, Wheeler TT, Casey T, German JB, Lemay DG, Maqbool NJ, Molenaar AJ, Seo S, Stothard P, Baldwin CL, Baxter R, Brinkmeyer-Langford CL, Brown WC, Childers CP, Connelley T, Ellis SA, Fritz K, Glass EJ, Herzig CT, Iivanainen A, Lahmers KK, Bennett AK, Dickens CM, Gilbert JG, Hagen DE, Salih H, Aerts J, Caetano AR, Dalrymple B, Garcia JF, Gill CA, Hiendleder SG, Memili E, Spurlock D, Williams JL, Alexander L, Brownstein MJ, Guan L, Holt RA, Jones SJ, Marra MA, Moore R, Moore SS, Roberts A, Taniguchi M, Waterman RC, Chacko J, Chandrabose MM, Cree A, Dao MD, Dinh HH, Gabisi RA, Hines S, Hume J, Jhangiani SN, Joshi V, Kovar CL, Lewis LR, Liu YS, Lopez J, Morgan MB, Nguyen NB, Okwuonu GO, Ruiz SJ, Santibanez J, Wright RA, Buhay C, Ding Y, Dugan-Rocha S, Herdandez J, Holder M, Sabo A, Egan A, Goodell J, Wilczek-Boney K, Fowler GR, Hitchens ME, Lozado RJ, Moen C, Steffen D, Warren JT, Zhang J, Chiu R, Schein JE, Durbin KJ, Havlak P, Jiang H, Liu Y, Qin X, Ren Y, Shen Y, Song H, Bell SN, Davis C, Johnson AJ, Lee S, Nazareth LV, Patel BM, Pu LL, Vattathil S, Williams RL Jr, Curry S, Hamilton C, Sodergren E, Wheeler DA, Barris W, Bennett GL, Eggen A, Green RD, Harhay GP, Hobbs M, Jann O, Keele JW, Kent MP, Lien S, McKay SD, McWilliam S, Ratnakumar A, Schnabel RD, Smith T, Snelling WM, Sonstegard TS, Stone RT, Sugimoto Y, Takasuga A, Taylor JF, Van Tassell CP, Macneil MD, Abatepaulo AR, Abbey CA, Ahola V, Almeida IG, Amadio AF, Anatriello E, Bahadue SM, Biase FH, Boldt CR, Carroll JA, Carvalho WA, Cervelatti EP, Chacko E, Chapin JE, Cheng Y, Choi J, Colley AJ, de Campos TA, De Donato M, Santos IK, de Oliveira CJ, Deobald H, Devinoy E, Donohue KE, Dovc P, Eberlein A, Fitzsimmons CJ, Franzin AM, Garcia GR, Genini S, Gladney CJ, Grant JR, Greaser ML, Green JA, Hadsell DL, Hakimov HA, Halgren R, Harrow JL, Hart EA, Hastings N, Hernandez M, Hu ZL, Ingham A, Iso-Touru T, Jamis C, Jensen K, Kapetis D, Kerr T, Khalil SS, Khatib H, Kolbehdari D, Kumar CG, Kumar D, Leach R, Lee JC, Li C, Logan KM, Malinverni R, Marques E, Martin WF, Martins NF, Maruyama SR, Mazza R, McLean KL, Medrano JF, Moreno BT, Moré DD, Muntean CT, Nandakumar HP, Nogueira MF, Olsaker I, Pant SD, Panzitta F, Pastor RC, Poli MA, Poslusny N, Rachagani S, Ranganathan S, Razpet A, Riggs PK, Rincon G, Rodriguez-Osorio N, Rodriguez-Zas SL, Romero NE, Rosenwald A, Sando L, Schmutz SM, Shen L, Sherman L, Southey BR, Lutzow YS, Sweedler JV, Tammen I, Telugu BP, Urbanski JM, Utsunomiya YT, Verschoor CP, Waardenberg AJ, Wang Z, Ward R, Weikard R, Welsh TH Jr, White SN, Wilming LG, Wunderlich KR, Yang J, Zhao FQ.
Science. ; 324(5926):522-8.


Request Update