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Candice Brinkmeyer-Langford

Postdoctoral Research Associate

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Phone: (979) 845-6780

Mailstop: 4458

Department: VIBS

Photo of Brinkmeyer-Langford, Candice

Education

  • Ph.D. Genetics, Texas A&M University 2006

Scholarly Interests

My primary research focus is genomics. I am particularly interested in comparative genomics: learning about the dynamics underlying human diseases by studying their counterparts in animals. Currently I am studying a model of the human disease Duchenne muscular dystrophy known as Golden Retriever muscular dystrophy (GRMD). In both humans and dogs, this disease is caused by a genetic defect in a single gene, yet the amount of variation seen in the clinical signs of the disease suggests that other elements contribute to its presentation, progression, and overall severity. At this time, I am working to understand these modifying factors in GRMD, knowing that the findings can be used in the future to develop targeted treatments for the human disease.

Publications

A conserved segmental duplication within ELA.
Brinkmeyer-Langford CL, Murphy WJ, Childers CP, Skow LC.
Anim Genet. 2010 Dec; 41 Suppl 2:186-95.
PMID: 21070294 [PubMed - in process]
A high resolution RH map of the bovine major histocompatibility complex.
Brinkmeyer-Langford CL, Childers CP, Fritz KL, Gustafson-Seabury AL, Cothran M, Raudsepp T, Womack JE, Skow LC.
BMC Genomics. 2009 Apr; 10:182.
PMID: 19393056 [PubMed - indexed for MEDLINE]
A 4,103 marker integrated physical and comparative map of the horse genome.
Raudsepp T, Gustafson-Seabury A, Durkin K, Wagner ML, Goh G, Seabury CM, Brinkmeyer-Langford C, Lee EJ, Agarwala R, Stallknecht-Rice E, Schäffer AA, Skow LC, Tozaki T, Yasue H, Penedo MC, Lyons LA, Khazanehdari KA, Binns MM, MacLeod JN, Distl O, Guérin G, Leeb T, Mickelson JR, Chowdhary BP.
Cytogenet Genome Res. 2008 ; 122(1):28-36.
PMID: 18931483 [PubMed - indexed for MEDLINE]
A high-resolution physical map of equine homologs of HSA19 shows divergent evolution compared with other mammals.
Brinkmeyer-Langford C, Raudsepp T, Lee EJ, Goh G, Schäffer AA, Agarwala R, Wagner ML, Tozaki T, Skow LC, Womack JE, Mickelson JR, Chowdhary BP.
Mamm Genome. 2005 Aug; 16(8):631-49.
PMID: 16180145 [PubMed - indexed for MEDLINE]