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Research Faculty Directory

Researchers in the College of Veterinary Medicine & Biomedical Sciences (CVM) embody the spirit of discovery and channel their enthusiasm into projects examining the underlying molecular and biochemical mechanisms of diseases in livestock, companion, wild, and exotic species. Our multidisciplinary group of clinical and basic investigators is engaged in cutting edge research that directly impacts both veterinary and human medicine. The CVM collectively receives more than $13 million dollars in state, federal, and private funding each year.

Research Building

The college has 5 academic departments and two service departments including the veterinary medical teaching hospital (small and large animal clinics) and the Texas Institute for Preclinical Studies (TIPS) which provide a stimulating environment fostering translational research that will shape the future. We have approximately 250 faculty members in our college that are actively engaged in research, teaching and service.

The CVM has faculty members from many diverse research areas, including our seven signature programs are conducting interdisciplinary research projects on basic, translational and clinical biomedical research.  The findings of these projects have been reported in prestigious journals, including Nature, Science, Cell, and Proceeding of the National Academy of Sciences.  This research is supported by federal, state, and private agencies, such as NIH, USDA, and Morris Animal Foundation.

A major aspect of our mission is to train future scientists and clinicians in the cutting edge biomedical techniques and ensure they are on the forefront of their areas of expertise. We have over 130 graduate students and numerous undergraduate students that are actively engaged in research.


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Abbott, Louise Professor VIBS
Areas of Specialization:
Toxicology, Neuroscience
Scholarly Interests:
developmental toxicology with special focus on the effects of mercury on the developing nervous system.
Adams, Garry Senior Professor VTPB
Areas of Specialization:
Immunology, Cell Biology, Genomics, Infectious Disease, Pathology, Microbiology, Biodefense, Food Animal, Education
Scholarly Interests:
I have long been intrigued with the biological interface between hosts and etiological agents, and the resulting patterns of morphological lesions, especially lesions caused by infectious disease agents. The morphologic, cytokine/chemokine, transcriptomic, proteomic and metabolomic patterns of host and pathogen responses provoke a series of fundamental questions, e.g. what is the molecular pathogenesis of these lesions?; does the host genome manipulate the pathogen or vice versa?; what host and pathogen cellular pathways are perturbed and dysfunctional in the disease processes?; what is the cause of death?; can we apply genomic pathology (the convergence of ‘omics’ and morphology) and systems biology to more fully understand infection biology as the basis for improved prediction of host and pathogen mechanistic genes and pathways critical to health and clinical illness? In response to these questions, my research is focused on the: 1) investigation of the comparative molecular pathogenesis of zoonotic intracellular bacterial pathogens in natural animal models, particularly salmonellosis, brucellosis and mycobacterial diseases, 2) development of vaccines and host gene expression-based diagnostics for zoonotic and select agent caused diseases, and especially 3) development of in silico host:pathogen interactome predictive models based upon bi-directional in vivo host (bovine/murine) and Salmonella enterica Typhimurium interactions at the target organ interface, enteric Peyer’s patches. The vision to develop improved animal models for salmonellosis originated in the early 2000s in association with my collaborators, Drs. Andreas Bäumler and Renee Tsolis. From our very successful and continuing collaboration grew the idea to develop a computational infection biology model based on temporal neonatal calf in vivo microarray-based transcriptomic and proteomic profiling of the acute Salmonella infection process. We expanded our research team by including Drs. Sara Lawhon, Kenneth Drake and Harold ‘Skip’ Garner, focusing on an envisioned systems biology analysis of both host and pathogen comprehensive transcriptomic and proteomic datasets derived from our in vivo biological model. We next computationally fused the datasets based on actual Salmonella proteomic data (performed by Dr. Mary Lipton at Pacific Northwest National Laboratory) and computationally predicted bovine host structural proteins to identify maximum likelihoods of host and pathogen protein:protein interactions as the basis for our preliminary in silico interactome model to predict mechanistic genes and linked perturbed cellular pathways. We then established in vitro phenotypes of S. Typhimurium deletion mutants (provided by Dr. Helene Andrews-Polymenis) of the predicted mechanistic genes for attachment, invasion or survival in murine RAW 264.7 macrophages to confirm almost half of the modeled predictions. Finally, over half of the model-predicted and in vitro-confirmed S. Typhimurium genes were validated to have in vivo phenotypes in our bovine ligated ileal loop model. We subsequently performed siRNA knockdowns in RAW 264.7 macrophages of predicted host proteins interacting with Salmonella proteins and validated in vitro phenotypes in almost half of the predicted host genes. Our lab proposes to significantly enhance the predictability of the in silico interactome model by adding the NEXTGen sequencing transcriptomics, advanced proteomics and metabolomics. By fusing higher quality genomic, transcriptomic, proteomic and metabolomic datasets derived from in vivo S. Typhimurium comparative infection models in mice, calves and non-human primates, we propose to further enhance the predictability and validation of in silico interactome model as a tool for the ultimate practice of “precision human medicine” as envisioned by the 2011 report by the National Academy of Sciences. As our publications document, we have also developed in silico interactome modeling tools for intracellular bacterial pathogens, Brucella melitensis and Mycobacterium avium ssp. paratuberculosis, all based on in vivo datasets. Our team has published 42 peer-reviewed manuscripts on salmonellosis using animal models, confirming our combined abilities to perform complex series of in vivo and in vitro experiments and developing high level in silico predictive models as we propose here. My long term role as co-developer of our in vivo based in silico interactome predictive model and personal collaborations with each of our team of investigators and core directors enables us to envision developing the in silico interactome predictive model for the biomedical research community.
Amstalden, Katia Research Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Rodent Phenotyping, animal behavior, animal models, and neuroscience
Andrews-Polymenis, Helene Associate Professor - Joint Appointment VTPB
Areas of Specialization:
Food Safety, Genomics, Genetics, Infectious Disease, Pathology, Microbiology
Scholarly Interests:
Arnold, Carolyn Assistant Professor VLCS
Areas of Specialization:
Infectious Disease, Surgery, Microbiology
Scholarly Interests:
My research interest is in the area of antibiotic-associated diarrhea in horses.
Arosh, Joe Associate Professor VIBS
Areas of Specialization:
Scholarly Interests:
central role of prostaglandins on molecular and cellular aspects of reproductive processes, gynecologic diseases and endocrine cancers.
August, John Associate Dean of Faculties & Director of Center for Teaching Excellence VSCS
Areas of Specialization:
Medicine, Education
Scholarly Interests:
Feline internal medicine; distance education; educational technology
Baetge, Courtney Clinical Assistant Professor VSCS
Areas of Specialization:
Anesthesia
Scholarly Interests:
Anesthesia and Pain management specifically as it relates to small animal geriatrics, donkey and equine TIVA, equine post anesthetic myelopathy and HYPP and avian anesthesia.
Bailey, Murl Professor VTPP
Areas of Specialization:
Scholarly Interests:
Toxicology; veterinary toxicology; toxic plants; wildlife, and environmental toxicology; anesthesiology; pharmacology; experimental surgery; clinical medicine; emergency medicine, bioterrorism, weapons of mass destruction.
Ball, Judith Associate Professor VTPB
Areas of Specialization:
Toxicology, Cell Biology, Oncology, Virology, Field Service (Livestock)
Scholarly Interests:
Our studies focus on the molecular and biochemical aspects of viruses, interactions of viral proteins with host cell moieties and intracellular transport. The overall goal of our work is to identify unique therapeutic targets for viral intervention. We employ a multitude of techniques such as yeast two-hybrid assays, laser-scanning confocal microscopic techniques (single and multiphoton), synthetic peptide chemistry, protein analyses and mutagenesis studies. Our primary interest is rotavirus, the single most important cause of pediatric, life-threatening gastroenteritis that annually claims ~610,000 young lives worldwide and results in hospitalization of 1 in 60 children in the U.S. at an annual cost of one billion dollars. We also study other viral systems that impact human and animal health with a focus on dissecting the association viral proteins with plasma membrane microdomains, such as caveolae.
Banu, Sakhila Assistant Professor VIBS
Areas of Specialization:
Toxicology, Reproductive Biology, Environmental Health, Oncology
Scholarly Interests:
Endocrine toxicology; endocrine oncology; reproductive toxicity of chromium-VI on ovarian development and function, pregnancy, and fetal development; vitamin C and nutrioxidants' intervention on heavy metal-induced toxicity; prostaglandin E2 biosynthesis, signaling and transport on mammary gland cancer development
Barhoumi Mouneimne, Roula Research Professor VIBS
Areas of Specialization:
Toxicology, Imaging
Scholarly Interests:
Dietary effects on polycyclic aromatic hydrocarbons metabolites and their activation under different circadian rhythms. Development of methods in the fluorescence microscopy field that achieve data acquisition and analysis in real time, quantitative analysis, and mathematical modeling of cellular signaling. Development of novel technological tools to decipher molecular and physiological events in cells and immunological tissues under normal toxin exposure and disease conditions.
Barr, James Assistant Professor VSCS
Areas of Specialization:
Medicine
Scholarly Interests:
Mechanical ventilation; coagulation; fluid therapy; cytokine response in sepsis
Barton, Claudia Professor VSCS
Areas of Specialization:
Scholarly Interests:
Oncology; aspiration cytology; small animal reproduction
Bazer, Fuller Distinguished Professor VIBS
Areas of Specialization:
Immunology, Reproductive Biology, Cell Biology, Physiology, Food Animal, Education
Scholarly Interests:
Reproductive biology with emphasis on uterine biology and pregnancy. Mechanisms of action of pregnancy recognition signals from the conceptus to the maternal uterus, including interferon tau and estrogen from ruminant and pig conceptuses, respectively, are studied at the molecular and cellular levels. The roles of uterine secretions as transport proteins, regulatory molecules, growth factors and enzymes and endocrine regulation of their secretion is another major research interest. The endocrinology of pregnancy, especially the roles of lactogenic and growth hormones in fetal-placental development and uterine functions are being studied. The mechanism(s) of action and potential therapeutic value of conceptus interferons and uterine-derived hematopoietic growth factors are areas of research with both pigs and sheep as models for human disease.
Beaver, Bonnie Professor VSCS
Areas of Specialization:
Scholarly Interests:
Normal and abnormal domestic animal behavior; human-animal interrelationships; animal welfare
Bennett, Brad Lecturer VSCS
Areas of Specialization:
Scholarly Interests:
Berghman, Luc Associate Professor-Joint Appointment VTPB
Areas of Specialization:
Immunology, Biodefense, Avian Medicine
Scholarly Interests:
Major goals of my program are (1) to acquire fundamental new knowledge of the avian immune system, especially antigen presentation and (2) to apply this new knowledge toward the development of novel immuno-biotechnological tools, such as vaccines, immunoassays and diagnostics. Basic avian immune studies include the study of cellular and humoral interactions, especially those involving the chicken professional antigen-presenting cells (APC)s (macrophages, dendritic cells and B-cells). Immuno-biotechnological applications include the development of monoclonal antibodies (a routine procedure and hallmark of our lab), polyclonal antibodies (incl. in chicken egg yolk), and recombinant antibodies for diagnostic, prophylactic and therapeutic purposes. Current projects feature the development of antibody-guided 'smart' vaccines, and the development of immunodiagnostic and analytical tools for the detection of a wide variety of molecules and microorganisms.
Bergthrosson, Ulfar Visiting Associate Professor VTPP
Areas of Specialization:
Scholarly Interests:
Bissett, Wesley Associate Professor & Director of the Veterinary Emergency Team VLCS
Areas of Specialization:
Epidemiology, Toxicology, Environmental Health, Disaster Management, Education
Scholarly Interests:
Veterinary emergency response, environmental health, epidemiology, and public health.
Blanchard, Terry Professor VLCS
Areas of Specialization:
Reproductive Biology
Scholarly Interests:
Theriogenology and ambulatory emergency. Stallion and mare reproduction; management strategies to improve stallion fertility; stallion testicular dysfunction.
Blue-McLendon, Alice Clinical Assistant Professor VTPP
Areas of Specialization:
Physiology, Zoo, Exotic and Wildlife Medicine
Scholarly Interests:
Veterinary physiology, avian reproductive physiology, medicine of exotic animals, management of exotic animals teaching and research projects
Bolling, Melanie Lecturer VSCS
Areas of Specialization:
Scholarly Interests:
Boudreau, Beth Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Bray, Jeffrey Research Associate VTPP
Areas of Specialization:
Scholarly Interests:
Brightsmith, Donald Assistant Professor VTPB
Areas of Specialization:
Environmental Health, Infectious Disease, Ecology
Scholarly Interests:
Avian diseases; avian ecology; geophagy (consumption of soil); avian conservation; disease threats from the live bird trade; diets of wild and captive exotic birds; role of infectious diseases in wild and endangered bird populations. Specialization in psittacines (parrots, macaws, parakeets and allies).
Brinkmeyer-Langford, Candice Research Assistant Professor VIBS
Areas of Specialization:
Immunology, Neuroscience, Genomics, Genetics
Scholarly Interests:
My primary research focus is genomics. I am particularly interested in comparative genomics: learning about the dynamics underlying human diseases by studying their counterparts in animals. Currently I am studying a model of the human disease Duchenne muscular dystrophy known as Golden Retriever muscular dystrophy (GRMD). In both humans and dogs, this disease is caused by a genetic defect in a single gene, yet the amount of variation seen in the clinical signs of the disease suggests that other elements contribute to its presentation, progression, and overall severity. At this time, I am working to understand these modifying factors in GRMD, knowing that the findings can be used in the future to develop targeted treatments for the human disease.
Brinsko, Steven Professor & Associate Department Head for Academic Programs VLCS
Areas of Specialization:
Reproductive Biology
Scholarly Interests:
Equine theriogenology. Sperm membrane function; and semen preservation.
Budke, Christine Associate Professor VIBS
Areas of Specialization:
Epidemiology, Public Health
Scholarly Interests:
Epidemiology; burden of disease indicators; zoonotic diseases (larval cestodes); transmission dynamics of parasitic diseases; international veterinary medicine and public health.
Burghardt, Robert Associate Dean for Research and Graduate Studies DCVM
Areas of Specialization:
Toxicology, Reproductive Biology, Cell Biology, Environmental Health, Imaging
Scholarly Interests:
Reproductive biology, toxicology/environmental health; use of non-invasive imaging technologies to investigate the mechanisms by which biological response modifiers ranging from hormones and growth factors to environmental chemicals alter cellular signaling pathways and cellular homeostasis
Cai, James Assistant Professor VIBS
Areas of Specialization:
Genomics, Genetics, Infectious Disease, Microbiology
Scholarly Interests:
Our research focuses on elucidation of genotype-phenotype relationships using computational and evolutionary genomics approaches. We develop computational tools and statistical tests to estimate key parameters of evolutionary processes that shape the sequence and expression variability within and between individuals, populations, and species. We apply theories to genomic diversity and divergence data in order to search for the signatures of selection in the genomes of different organisms.
Cannon, Marvin Visiting Professor VIBS
Areas of Specialization:
Scholarly Interests:
Carroll, Gwendolyn Professor VSCS
Areas of Specialization:
Pharmacology, Laboratory Animal Medicine, Zoo, Exotic and Wildlife Medicine, Avian Medicine, Food Animal
Scholarly Interests:
pharmacology and pharmacodynamics of novel analgesics and anesthetics and their method of delivery in minor species and cats
Carter, Kent Professor & Assistant Department Head for Animal Resources VLCS
Areas of Specialization:
Scholarly Interests:
Equine lameness
Chaffin, Keith Professor & Assistant Department Head for Clinical Programs VLCS
Areas of Specialization:
Scholarly Interests:
Equine internal medicine, pediatrics, respiratory disease and ultrasonography; Rhodococcus equi foal pneumonia; equine infectious disease; equine gastrointestinal disease; equine urogenital disease; and equine neurologic disease.
Chaki, Sankar Research Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Chapkin, Robert Professor - Joint Appointment VIBS
Areas of Specialization:
Scholarly Interests:
chemoprevention; dietary effects on chronic inflammation, T-cell biology and colon cancer; plasma membrane microdomain organization and protein trafficking; functional genomics and systems biology.
Chiu, Weihsueh Professor VIBS
Areas of Specialization:
Toxicology, Environmental Health, Public Health
Scholarly Interests:
My research focuses on the development of quantitative, data-driven approaches for understanding and predicting the human health effects of environmental chemicals. Specifically, my research applies computational and statistical methods to transform data into knowledge used to protect public health. I also have an interest in approaches to estimate the variability in individual susceptibility to environmental exposures, so as to better protect sensitive subpopulations.
Choi, Young Research Scientist VTPP
Areas of Specialization:
Scholarly Interests:
Chowdhary, Bhanu Professor VIBS
Areas of Specialization:
Genomics, Genetics, Education
Scholarly Interests:
comparative genomics of domesticated animals; molecular cytogenetics; equine genome analysis; physical and comparative gene mapping; disease genetics; molecular analysis of equine fertility; functional analysis of the equine genome.
Ciepluch, Michael Lecturer VSCS
Areas of Specialization:
Scholarly Interests:
Clark, Brooke Lecturer VSCS
Areas of Specialization:
Scholarly Interests:
Emergency/critical care medicine; internal medicine
Clavijo, Alfonso Research Professor, Joint Appointment VTPB
Areas of Specialization:
Scholarly Interests:
Dr. Clavijo is currently a senior science advisor at the Institute for Infectious Animal Diseases (IIAD) and Research professor at the College of Veterinary Medicine of the Texas A&M University. His main research focus includes development and validation of novel diagnostic assays for transboundary animal diseases and zoonoses and the production of monoclonal antibodies, recombinant proteins and molecular probes as diagnostic reagents. Dr. Clavijo has a broad experience in laboratory diagnosis of Foot-and-mouth disease, African swine fever, classical swine fever and other transboundary animal diseases.
Clubb, Fred Clinical Professor VTPB
Areas of Specialization:
Pathology, Imaging, Cardiology, Diagnostic Imaging
Scholarly Interests:
Electron microscopic evaluation of myocardial and renal biopsies; qualitative and quantitative evaluation of implantable cardiovascular devices for nonGLP and GLP \preclinical trials.
Cohen, Noah Professor & Associate Department Head for Research and Graduate Studies VLCS
Areas of Specialization:
Epidemiology, Genomics, Genetics, Infectious Disease, Medicine, Microbiology
Scholarly Interests:
Equine internal medicine. Special Interests: equine gastroenterology, infectious diseases, and neurology. Director, Equine Infectious Disease Laboratory.
Coleman, Michelle Lecturer/PhD Student VLCS
Areas of Specialization:
Epidemiology
Scholarly Interests:
Epidemiology
Cook, Audrey Associate Professor VSCS
Areas of Specialization:
Medicine
Scholarly Interests:
Endocrinology; gastroenterology; endoscopy and interventional radiology.
Cook, Walt Clinical Associate Professor VTPB
Areas of Specialization:
Scholarly Interests:
Cothran, Jr., Ernest (Gus) Clinical Professor VIBS
Areas of Specialization:
Genomics, Genetics
Scholarly Interests:
heredity basis of equine congenital defects and economically significant traits in domestic animals (mainly the horse); interrelationships of inbreeding, genetic polymorphism, and reproductive performance in horses; population genetics of feral horses; comparative aspects of genetics variation in horses under human selection and under natural selection; genetic aspects of captivity; genetics of domestication. Management of genetic polymorphism in small populations and conservation of rare breeds; genetic relationship among domestic horse breeds; changes in gene regulation based upon environmental factors; gene mapping of the horse.
Craig, Thomas Professor VTPB
Areas of Specialization:
Epidemiology, Genomics, Infectious Disease, Public Health, Parasitology, Ecology, Production Medicine, Zoo, Exotic and Wildlife Medicine, Food Animal
Scholarly Interests:
Transmission patterns of infections of prokaryotic and eukaryotic parasites and the control of disease caused by these parasites. Control of parasites resistant to extant pharmaceuticals by selection of hosts with phenotype resistance to parasites and the selection of parasites with phenotypes susceptible to extant pharmaceuticals.
Criscitiello, Michael Associate Professor VTPB
Areas of Specialization:
Immunology, Toxicology, Genomics, Genetics, Infectious Disease, Education
Scholarly Interests:
My Comparative Immunogenetics Laboratory http://vetmed.tamu.edu/comparative-immunogenetics-lab studies immunology and evolution. Most of our research focuses on the early natural history of the vertebrate adaptive immune system, with particular attention given to the genetics of lymphocyte antigen receptors, mucosal immune mechanisms in the gut, antigen presentation and invertebrate innate immunogenomics. Our goals are bipartite, but related. Our first aim is to understand the evolution of our immune system: its genesis, subsequent natural history, and trajectory into the future. We pursue this using the comparative method focusing on evolutionarily strategic poikilothermic vertebrates (frog and shark) and economically important food species (shrimp, cattle and tuna). This work allows us to distinguish what aspects are phylogenetically fundamental in our own system and differentiate those that are merely accessory. Our second aim is to continue to discover and understand the many diverse tools less-studied organisms have evolved in their defensive batteries, which mouse and man often lack. These novel receptors, mechanisms, domains and tissue architectures will inform better vaccine development, biomedical engineering and clinical intervention for the better health of all animals.
Cummings, Kevin Assistant Professor VIBS
Areas of Specialization:
Epidemiology, Food Safety, Infectious Disease, Public Health
Scholarly Interests:
My research focuses on the use of analytic and molecular epidemiology to study Salmonella and other foodborne pathogens at the pre-harvest level.  Work is targeted at minimizing zoonotic transmission of pathogens that threaten food safety, as well as reducing disease burden among veterinary species. Additional areas of interest include emerging infectious diseases, antimicrobial resistance, and hospital biosecurity.
Curley, Jr., Kevin Lecturer VIBS
Areas of Specialization:
Science/Tech Journalism
Scholarly Interests:
science communication; educational technology; web-based learning
Dabareiner, Robin Associate Professor VLCS
Areas of Specialization:
Scholarly Interests:
Equine lameness
Dai, Susie Research Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
My research interests focus on several aspects: 1) Proteomics and interactomics in cancer and bioenergy. 2) Protein structure dynamics and structure-function relationship study with a focus in nuclear receptor and cellulase enzymes. 3) Biomonitoring programs which include analyzing veterinary drugs, mycotoxins, etc., in feed and food. We utilize a variety of techniques including shotgun proteomics, hydrogen deuterium exchange mass spectrometry and mass-spec based multiple target analysis. The major goals of the lab are: 1) Establish systems biology approaches to characterize and elucidate protein-protein interaction and mechanistic study of protein functions with the ultimate goal for novel therapies in cancer and breakthroughs for bioenergy production. 2) Develop methods for food and feed safety monitoring programs in a high throughput, multiple residue based fashion.
Dangoudoubiyam, Sriveny Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Davidson, Jacqueline Clinical Professor VSCS
Areas of Specialization:
Surgery
Scholarly Interests:
Physical rehabilitation; pain management; soft tissue surgery; orthopedic surgery
Davis, Don Associate Professor VTPB
Areas of Specialization:
Infectious Disease, Ecology
Scholarly Interests:
Infectious and parasitic diseases of native, exotic and/or feral wildlife captive or free-ranging, particularly those shared with traditional domestic livestock, farmed/ranched ungulates, and/or humans, with emphasis on experimental, controlled infections to evaluate improved diagnostics vaccines suitable for wildlife, and the systems to deliver chemotherapeutic agents or vaccines to wildlife. Development of handling and restraint facilities appropriate for captive wildlife, and natural (genetic) disease resistance in wildlife. Brucellosis, tuberculosis, anthrax, hemaprotozoon, trematodes, and nematodes.
Dees, W. Les Professor VIBS
Areas of Specialization:
Toxicology, Reproductive Biology, Physiology
Scholarly Interests:
Factors controlling or altering the onset of female puberty.
deFigueiredo, Paul Associate Professor-Joint Appointment VTPB
Areas of Specialization:
Cell Biology, Genomics, Genetics, Infectious Disease, Pathology, Imaging, Microbiology, Biodefense
Scholarly Interests:
The de Figueiredo group exploits their expertise in cell biology, microbiology, molecular biology, genetics and genomics to tackle broad life science research questions.
Derr, James Professor VTPB
Areas of Specialization:
Genomics, Genetics, Infectious Disease
Scholarly Interests:
Molecular genetics of mammals including; characterization of genetic traits and disease, population and conservation genetics, and the evolution of genes and genomes at the nucleotide level in domestic and wild populations.
Deveau, Michael Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Developement and implementation of advanced radiotherapeutic strategies utilizing information from anatomical and functional diagnostic imaging, the flexibility of complimentary 3D printing technology, and dose conformity provided by helical tomotherapy.
Diesel, Alison Clinical Assistant Professor VSCS
Areas of Specialization:
Immunology, Infectious Disease, Oncology, Dermatology
Scholarly Interests:
Inflammatory skin conditions in animals, particularly feline allergic skin disease; skin associated side effects of radiation therapy
Dindot, Scott Associate Professor VTPB
Areas of Specialization:
Neuroscience, Genomics, Genetics, Education
Scholarly Interests:
My laboratory is interested in understanding the genetic and epigenetic mechanisms underlying phenotypic variation and disease. Research topics in my laboratory include genomic imprinting, epigenetic regulation of gene expression and genetic dissection of Mendelian and complex traits.
Dinges, Lewis Clinical Assistant Professor VLCS
Areas of Specialization:
Scholarly Interests:
Texas Department of Criminal Justice, Beef cattle production medicine.
Dodd, Johnathon Clinical Professor VSCS
Areas of Specialization:
Scholarly Interests:
Dentistry
Dominguez, Brandon Clinical Assistant Professor VLCS
Areas of Specialization:
Epidemiology, Infectious Disease, Public Health, Field Service (Equine), Field Service (Livestock), Production Medicine, Disaster Management
Scholarly Interests:
Livestock production medicine, particularly with swine and diseases that are transmissible between domestic and wild populations. Additionally, I seek to mitigate risk and enhance benefits of working with livestock populations and infectious diseases.
Dongaonkar, Ranjeet Assistant Professor VTPP
Areas of Specialization:
Physiology, Cardiology
Scholarly Interests:
Interstitial fluid balance; microvascular physiology; lymphatic function; quantitative analysis and modeling of physiological systems.
Easterwood, Leslie Clinical Assistant Professor VLCS
Areas of Specialization:
Oncology, Dermatology, Field Service (Equine)
Scholarly Interests:
Equine medicine. Skin tumors in horses, and equine ophthalmology
Eckman, Stacy Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Feline medicine; zoonotic diseases of companion animals; preventative medicine
Edwards, John Professor VTPB
Areas of Specialization:
Food Safety, Reproductive Biology, Infectious Disease, Pathology, Virology
Scholarly Interests:
Diagnostic pathology, infectious diseases of domestic livestock particularly of cattle and horses; in utero teratogenicity (viral and toxic), pathology of the reproductive system and infertility; diseases of the fetus and neonate; food safety of red meat species, pathology of animals at slaughter.
Ellis, Cheryl Lecturer VLCS
Areas of Specialization:
Scholarly Interests:
Esteve-Gassent, Maria Assistant Professor VTPB
Areas of Specialization:
Infectious Disease, Pathology
Scholarly Interests:
My laboratory is interested in understanding how Borrelia burgdorferi, the causative agent of Lyme disease, counteracts oxidative and nitrosative stress upon transmission to the mammalian host. The ability of B. burgdorferi to colonize mammals is dependent on its ability to rapidly alter gene expression in response to highly disparate environmental signals following transmission from infected ticks. Furthermore, this bacterium has a very limited number of genes involved in counteracting oxidative and nitrosative stress, with one single superoxide dismutase (sodA) and no typical catalases and peroxidases. We have demonstrated that the sodA gene is essential for infectivity in the mouse model. Therefore, our goal is to further analyze the molecular mechanisms adopted by B. burgdorferi to combat reactive oxygen and nitrogen species, and to dissect critical physiological responses against these stressors in the processes facilitating colonization of the mammalian hosts. We are also interested in a new family of membrane proteins, known as von Willebrand factor A containing proteins (VWFA), which have been described in other bacterial pathogens as potential adhesines. Our main goal is to understand the topology, insertion in the membranes and function of these proteins in B. burgdorferi during transmission from the infected tick to the mammalian host.
Fajt, Virginia Clinical Associate Professor VTPP
Areas of Specialization:
Pharmacology, Food Animal, Education
Scholarly Interests:
Clinical pharmacology, Pharmacokinetics and pharmacodynamics, Antimicrobials and antimicrobial resistance, Student learning and outcomes assessment, Food animal pharmacology
Ficht, Thomas Professor VTPB
Areas of Specialization:
Immunology, Cell Biology, Genomics, Genetics, Infectious Disease, Public Health, Pathology, Microbiology, Biodefense
Scholarly Interests:
Mechanisms of invasion and survival of intracellular bacteria within host cells; study of bacterial and host gene expression during infection and its use in the development and application of biosignatures; development of improved vaccines using genetic approaches to attenuate survival and identify therapeutic targets; development of subunit vaccines. Characterization of bacterial population structures through genomic analysis.
Frank-Cannon, Tamy Clinical Assistant Professor VIBS
Areas of Specialization:
Scholarly Interests:
Funkhouser, Norma Associate Professor - Joint Appointment VIBS
Areas of Specialization:
Scholarly Interests:
Information management education; organization, retrieval and database searching methods; new technology for information management; computer-aided instruction; web-based instruction/tutorials
Gastel, Barbara Professor VIBS
Areas of Specialization:
Science/Tech Journalism, Education
Scholarly Interests:
science journalism, medical journalism, science editing, international communication of science
Gibbons, Philippa Clinical Assistant Professor VLCS
Areas of Specialization:
Production Medicine
Scholarly Interests:
Small Ruminant Urolithiasis
Gilmour, Lindsey Clinical Assistant Professor VLCS
Areas of Specialization:
Scholarly Interests:
Magnetic Resonance Imaging, Computed Tomography, Ultrasound, Nuclear Medicine, and Radiography in Large and Small Animals
Golding, Michael Assistant Professor VTPP
Areas of Specialization:
Neuroscience, Reproductive Biology, Cell Biology, Genetics, Neurology, Physiology
Scholarly Interests:
Problems during pregnancy are responsible for several childhood disabilities including seizures and delayed abilities to speak and walk. These disabilities often show up in the children of mothers with medical conditions that cause significant hormonal problems or who drank alcohol during their pregnancy. My laboratory is interested in studying how these birth defects and mental disabilities develop and what treatments can be given in order to prevent them. I am an assistant professor within the department of veterinary physiology and pharmacology at Texas A&M University. Here, I serve as the instructor of record for two courses studying human embryology and the physiological events of pregnancy. My research program focuses on understanding the biochemical mechanisms by which chromosome structure is altered during development and how these changes serve to regulate gene expression. I am interested in understanding the mechanisms that recruit epigenetic modifiers to specific cohorts of genes, identifying the biochemical machinery directing this process, and understanding how these events are impacted by environmental toxins and teratogens. For the past four years, my laboratory has focused on epigenetic defects arising as a consequence of prenatal alcohol exposure.
Gordon, Sonya Associate Professor VSCS
Areas of Specialization:
Cardiology
Scholarly Interests:
My research interests include the diagnosis, staging, treatment and prognosis of canine chronic valvular disease and dilated cardiomyopathy, the clinical utility of cardiac biomarkers and echocardiography in dogs and cats, interventional cardiology and clinical trials.
Grayton, Jesse Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Green, Eleanor Carl B. King Dean of Veterinary Medicine DCVM
Areas of Specialization:
Scholarly Interests:
Griffin, Cleet Clinical Assistant Professor VLCS
Areas of Specialization:
Scholarly Interests:
Equine field service. Topics and clinical problems related to equine dentistry
Griffin, Jay Assistant Professor VLCS
Areas of Specialization:
Neuroscience, Neurology, Diagnostic Imaging, Radiology
Scholarly Interests:
My research involves the development of MRI techniques to diagnose disease, quantify lesion burden, and assess response to therapy. Specific areas of interest include spinal cord injury in dogs and MRI of metallic orthopedic implants.
Griffin, Sarah Lecturer VSCS
Areas of Specialization:
Scholarly Interests:
Emergency medicine; feline medicine; preventative medicine
Hamer, Sarah Assistant Professor VIBS
Areas of Specialization:
Epidemiology, Infectious Disease, Public Health, Parasitology, Ecology, Zoo, Exotic and Wildlife Medicine
Scholarly Interests:
Disease ecology and epidemiology; one health initiative; wildlife diseases; vector-borne diseases; ticks; Lyme disease and other tick-borne zoonoses; Chagas disease; conservation medicine
Han, Guichun Assistant Professor VTPP
Areas of Specialization:
Pathology, Pharmacology, Physiology
Scholarly Interests:
Cardiovascular physiology; vascular physiology and pharmacology, especially signaling pathways for estrogen and selective estrogen receptor modulator (SERM) effects on coronary artery; molecular mechanisms of estrogen receptors in vascular remodeling and hypertension.
Hardy, Joanne Clinical Associate Professor VLCS
Areas of Specialization:
Pharmacology, Physiology, Surgery, Lameness
Scholarly Interests:
Equine emergency and critical care. Gastrointestinal disorders in horses. Equine emergency and critical care. Equine guttural pouch mycosis.
Hartnack, Amanda Assistant Professor VLCS
Areas of Specialization:
Scholarly Interests:
Hartsfield, Sandee Retiree VSCS
Areas of Specialization:
Anesthesia
Scholarly Interests:
Anesthesiology with emphases on anesthetic machines and breathing systems, ventilators and ventilation in anesthetized patients, and the pharmacology and cardiovascular effects of general anesthetics and adjunctive drugs
Heaps, Cristine Associate Professor VTPP
Areas of Specialization:
Physiology
Scholarly Interests:
Determine exercise training-induced cellular and molecular adaptations in the coronary microcirculation that will reveal potential therapeutic targets for increasing blood flow into compromised myocardium
Heatley, J. Jill Associate Professor VSCS
Areas of Specialization:
Environmental Health, Zoo, Exotic and Wildlife Medicine, Avian Medicine
Scholarly Interests:
Clinical Pathology and Fluid Balance of Zoological Species; Emergency and Critical Care of Zoological Species; Rehabilitation and Reintroduction of Wildlife Oil Spill Response
Herman, Cheryl Clinical Associate Professor VIBS
Areas of Specialization:
Scholarly Interests:
veterinary gross anatomy
Herman, James Clinical Professor VTPP
Areas of Specialization:
Physiology
Scholarly Interests:
TEACHING -- Primary areas of interest in teaching include problem-based learning, development of creative thinking and problem solving capabilities, production of interactive multi-media programs for autotutorial use, and pedagogical research. RESEARCH -- Areas of interest in research include: outcomes assessment and educational evaluation, attribution theory, meta-analysis, and computer modeling of human physiology and pathophysiology. VETERINARY MEDICINE -- Interests and expertise in veterinary medicine encompasses wildlife, zoological, and laboratory animal medicine, zoonotic diseases, and public health.
Heseltine, Johanna Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Hillhouse, Andrew Research Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Hiney, Jill Research Assistant Professor VIBS
Areas of Specialization:
Toxicology, Neuroscience, Reproductive Biology, Anatomy
Scholarly Interests:
Hinrichs, Katrin Professor and Patsy Link Chair in Mare Reproductive Studies VTPP
Areas of Specialization:
Reproductive Biology
Scholarly Interests:
Oocyte maturation, sperm capacitation, fertilization, and embryo development in the horse, including intracytoplasmic sperm injection and nuclear transfer.
Hoffman, Anton Clinical Professor VIBS
Areas of Specialization:
Anatomy
Scholarly Interests:
1. Comparative and applied gross anatomy 2. Comparative clinical neuroanatomy 3. Surgical & radiographic anatomy 4. Medical illustration 5. Computer assisted instruction
Holman, Patricia Research Associate Professor VTPB
Areas of Specialization:
Immunology, Epidemiology, Cell Biology, Genetics, Infectious Disease, Parasitology, Microbiology, Zoo, Exotic and Wildlife Medicine
Scholarly Interests:
Molecular mechanisms driving interactions between Babesia spp. and their hosts; characterization of potential vaccine or drug targets for babesiosis; molecular phylogeny of the hemoparasites; genetic basis of bovine resistance/susceptibility to ectoparasitism; development of molecular diagnostic tests for piroplasms.
Hoppes, Sharman Clinical Associate Professor VSCS
Areas of Specialization:
Zoo, Exotic and Wildlife Medicine, Avian Medicine
Scholarly Interests:
Avian and exotic analgesia; proventricular dilation disease; aflatoxins in birds
Howe, Lisa Professor VSCS
Areas of Specialization:
Surgery
Scholarly Interests:
Upper respiratory disease; soft tissue surgery; perpubertal gonadectomy
Huang, Huan Assistant Research Scientist VTPP
Areas of Specialization:
Scholarly Interests:
Hulse, Don Veterinarian (Surgeon) VSCS
Areas of Specialization:
Scholarly Interests:
Comparative orthopedics; biodegradable implants; biomechanics of fracture fixation
Imanirad, Parisa Research Associate VTPP
Areas of Specialization:
Scholarly Interests:
Ing, Nancy Associate Professor - Joint Appointment VIBS
Areas of Specialization:
Reproductive Biology, Cell Biology, Genomics
Scholarly Interests:
I study steroid hormone action in reproductive tissues of animals
Ivanek-Miojevic, Renata Associate Professor VIBS
Areas of Specialization:
Epidemiology, Food Safety, Infectious Disease, Public Health, Ecology, Biodefense
Scholarly Interests:
Epidemiology and ecology of infectious and foodborne diseases; Addressing methodological research needs in epidemiology and ecology; Research at the interface between empirical and theoretical approaches to identify measures that would protect public and animal health; Analytical epidemiology; Mathematical modeling; Spatial epidemiology; Public health; Food safety; Risk assessment; Microarray analysis; Listeria monocytogenes; Escherichia coli; Salmonella spp.
Ivanov, Ivan Clinical Associate Professor VTPP
Areas of Specialization:
Toxicology, Environmental Health, Genomics, Public Health, Pharmacology
Scholarly Interests:
Computational predictive modeling of complex systems, e.g. gene regulatory networks, for the purposes of intervention and control. Omics-data processing and integration. Genomic Signal Processing.
Jeter, Elizabeth Lecturer VTPB
Areas of Specialization:
Scholarly Interests:
Animal Shelter Medicine - participates in the veterinary student rotations at the Brazos Valley Animal Shelter.
Johnson, Derek Lecturer VSCS
Areas of Specialization:
Scholarly Interests:
Johnson, Gregory Professor VIBS
Areas of Specialization:
Reproductive Biology
Scholarly Interests:
My laboratory utilizes pigs, sheep and mice to investigate the molecular, cellular and physiological interactions between the embryo/fetus and uterus during pregnancy recognition, implantation and placental development – with the ultimate goal of applying new knowledge towards clinical strategies to prevent pregnancy loss in women, livestock and companion animals.
Johnson, Larry Professor VIBS
Areas of Specialization:
Reproductive Biology, Anatomy, Physiology, Education
Scholarly Interests:
toxicology; histology; spermatogenesis; gamete physiology; gene expression of Sertoli cells; aging of the testis; seasonal reproductive changes; infertility in males and promotion of science in youth.
Johnson, Mark Clinical Associate Professor VTPB
Areas of Specialization:
Pathology
Scholarly Interests:
Professional courses in pathology and service/teaching responsibilities including clinical pathology hospital service. Diagnostic and investigative immunopathology with emphasis on immunohistochemistry and immunocytochemistry interpretations for characterization of lymphoma and other neoplasia.
Jones, Daniel Associate Professor VTPP
Areas of Specialization:
Toxicology
Scholarly Interests:
Veterinary and environmental toxicology
Jones, Meredyth Assistant Professor VLCS
Areas of Specialization:
Medicine, Lameness, Field Service (Livestock), Production Medicine, Food Animal, Education
Scholarly Interests:
My areas of research focus on beef cattle lameness, small ruminant parasite management and urolithiasis, and student learning methods.
Jutooru, Indira Assistant Research Scientist VTPP
Areas of Specialization:
Scholarly Interests:
Katju, Vaishali Associate Professor VIBS
Areas of Specialization:
Genetics
Scholarly Interests:
Kerwin, Sharon Professor & Tom and Joan Read Chair in Veterinary Surgery VSCS
Areas of Specialization:
Neurology, Surgery, Orthopedics, Lameness
Scholarly Interests:
My combined interest in orthopedics and neurology/neurosurgery encompasses lameness, gait analysis, fracture healing, osteoarthritis and spinal cord injury
Kier, Ann Professor VTPB
Areas of Specialization:
Reproductive Biology, Cell Biology, Genomics, Genetics, Pathology, Imaging, Medicine, Laboratory Animal Medicine, Zoo, Exotic and Wildlife Medicine, Anatomic Pathology
Scholarly Interests:
The long-term goal of my research is to understand how regulation of lipids (cholesterol, saturated versus unsaturated fatty acids) and glucose affect the pathogenesis of cardiovascular disease and diabetes through the use of cultured primary hepatocytes (human, mouse), gene-ablated, overexpression, and humanized mice as models for understanding human conditions, and to use these discovered mechanisms to exploit new drug development. Our current projects include investigating whether an intracellular fatty acid binding protein L-FABP mediates fibrate signaling to hepatic PPARα, an action potentiated by high glucose. Further, we propose that the human L-FABP T94A gene variant is impaired in its ability to function in this pathway, especially in the context of high glucose. We will be examining the collective physiologic impact of fibrates and human L-FABP T94A variant on signaling to PPARα in a humanized mouse model in vivo. The impact of human L-FABP T94A variant and glucose on fibrate nuclear targeting for PPARα interaction and activation is being examined via primary cultured human hepatocytes of WT and variant cells. I have the expertise, productivity, and interest needed to successfully carry out the proposed work. I am Director of a Transgenic Mouse Core Facility, and supervise the Injection and Morphology/Pathology Sections. I have a broad background in animal models, with specific training and expertise in key research areas in this application, including immunocytochemistry, primary hepatocyte culture, cell culture, construction of mammalian expression vectors, transfection, cloning of cells, in vivo lipid metabolism, and mouse phenotyping. As a Resident in Laboratory Animal Medicine and Postdoctoral Fellow in Comparative Pathology at the University of Missouri, I was trained in both human and laboratory animal pathology (comparative, experimental pathology) as well as earning Diplomate status in the American College of Laboratory Animal Medicine (ACLAM). At the University of Cincinnati Health Sciences Center, I furthered my expertise in animal models by learning gene-ablation techniques in the laboratory of Thomas Doetschman, collaborating on several NIH PO1 project grants as well as my own RO1 grants to clone the mouse gene coding for Hageman Factor and develop a genetically deficient mouse model. As Director of Comparative Pathology while teaching human pathology, I developed collaborations with Tom Doetschman, Steve Potter, Peter Stambrook, Jeffrey Robbins and other experts in the newly expanding field of mouse gene targeting to strengthen my expertise in mouse phenotyping and pathology, having PO1 components on 3 grants as well as PI and Co-I on RO1 grants, and publishing in Nature, Cell, J Biological Chemistry, and other high impact journals. While at Texas A&M University, I applied this expertise to develop and phenotype new mouse models overexpressing or ablated in genes encoding fatty acid and fatty acyl CoA binding proteins in collaboration with the PI of this proposal, Fred Schroeder. Other close collaborators include NAS members James Womack in mouse genetics/genomics, and Joanne Lupton in mouse nutrition/dietary studies. I have personnel trained in the specific areas of expertise needed for this application. The highly productive integration of different disciplines with the Dr. Friedhelm is particularly unique in our ability to follow key questions from the in vitro isolated protein level (Schroeder), through live cell culture imaging experiments (Schroeder and Kier), and in vivo into the molecular biological and physiologic environment of mouse models (Kier).
Klemm, William Senior Professor VIBS
Areas of Specialization:
Neuroscience, Neurology, Science/Tech Journalism, Education
Scholarly Interests:
My current interests are in cognitive neuroscience, science writing, and educational reform.
Ko, Gladys Associate Professor VIBS
Areas of Specialization:
Toxicology, Neuroscience, Cell Biology, Pharmacology, Physiology
Scholarly Interests:
The endogenous circadian clocks are important in regulating internal metabolic processes, physiological states, and behaviors, which are essential for organisms to anticipate the environmental changes that oscillate daily ( circa-dian =about one day). Misalignment of the endogenous clocks from the external time cues, such as in shift-workers and frequent across time-zone travelers, causes major health hazards with high risks in metabolic syndromes (such as diabetes), cardiovascular diseases, sleep disorders, and even cancers. In the eyes, retina is the neural tissue that receives and transmits the light information into the brain. The circadian clocks in the retina prepare this neural tissue to anticipate the upcoming light or darkness, since the ambient illumination changes throughout the course of a day over at least 12 orders of magnitude. Disruption of the retinal circadian clocks causes impaired visual function, which further impacts the light information transmitted into the brain. The circadian clock in the heart also prepares the heart muscles ready for the upcoming sympathetic stimulation, which is under the control of the master clock--the circadian clock inside the brain. Dysfunction of the circadian clock in the heart causes cardiac arrest and other cardiac diseases. We employ different techniques, including electrophysiological patch-clamp recordings, various biochemical and molecular assays, and cellular imaging to investigate how the circadian clocks regulate physiology and function in the retina and heart of both healthy and disease (diabetes) states.
Ko, Michael Research Assistant Professor VIBS
Areas of Specialization:
Neuroscience, Cell Biology
Scholarly Interests:
Korich, Jodi Clinical Assistant Professor VIBS
Areas of Specialization:
Science/Tech Journalism, Education
Scholarly Interests:
Dr. Korich is the founding director of the Educational Technology Center at Texas A&M University College of Veterinary Medicine and Biomedical Sciences. Established in 2010, the Educational Technology Center's mission is to research and develop innovative veterinary educational solutions. The Center’s team members work hand-in-hand with faculty and veterinarians from around the world to design, develop, and deliver world-class instructional materials. From online course ware to printed books, the Educational Technology Center specializes in creating customized products to meet learners' needs. As the Center’s director, Dr. Korich provides strategic program leadership, project management, instructional design, and serves as the principal investigator on the Center’s grants and contracts.
Kornegay, Joe Professor-Joint Appointment VIBS
Areas of Specialization:
Scholarly Interests:
Kraemer, Duane Senior Professor VTPP
Areas of Specialization:
Reproductive Biology, Cell Biology, Genetics, Oncology, Physiology
Scholarly Interests:
gamete and embryo physiology; embryo transfer, cloning, genetic engineering of mammals; preservation of endangered animals; contraception in animal pests.
Krecek, Rosina C (Tammi) Visiting Professor and Interim Assistant Dean for One Health VTPB
Areas of Specialization:
Scholarly Interests:
• One Health research with a focus on zoonotic parasitic and infectious diseases • Forging strategic partnerships with international and regional organizations in One Health research and training programs • Development of sustainable interventions emphasizing transmission and risk factors • Leading multidisciplinary teams that identify and implement sustainable solutions for prevention and management of diseases in developing communities
Laine, Glen Professor VTPP
Areas of Specialization:
Physiology, Cardiology
Scholarly Interests:
cardiovascular physiology; biophysics and bioengineering; quantitative analysis of biological systems; chronic venous and arterial hypertension and cardiopulmonary bypass; lymphatic function; edema formation and interstitial fibrosis.
Landis, Skip Retiree BIMS
Areas of Specialization:
Scholarly Interests:
Lawhon, Sara Assistant Professor VTPB
Areas of Specialization:
Infectious Disease, Microbiology
Scholarly Interests:
Work in my laboratory focuses on the molecular interactions between the Salmonella enterica and intestinal epithelial cells. I am particularly interested in how Salmonella spp. regulate gene expression in response to environmental signals and how mammalian hosts respond to Salmonella infection. I am also interested in how Salmonella spp. survive in the external environment and are transmitted within animal populations and antimicrobial resistance in Salmonella. In addition to our work in Salmonella, members of my laboratory study the role of methicillin resistance on survival and virulence of commensal and pathogenic Staphylococcus spp, particularly methicillin-resistant Staphylococcus pseudintermedius (MRSP).
Lees, George Retiree VSCS
Areas of Specialization:
Medicine
Scholarly Interests:
Urinary tract diseases of companion animals, especially glomerular diseases of dogs and renal pathology
Leibowitz, Julian Professor-Joint Appointment VTPB
Areas of Specialization:
Infectious Disease, Virology
Scholarly Interests:
The replication of the murine coronavirus MHV (mouse hepatitis virus) and the molecular and genetic basis of its interactions with the host are being studied. Coronaviruses are important human pathogens causing a broad range of diseases depending on the particular virus and host system examined. Human diseases associated with coronaviruses include SARS (severe acute respiratory syndrome), less severe lower and upper respiratory disease, and gastroenteritis. MHV produces a broad spectrum of disease in the mouse, and provides excellent small animal models for hepatitis, for SARS, and for multiple sclerosis.We have two projects in the laboratory. In collaboration with investigators in Toronto and Pennsylvania my laboratory has developed a MHV model for SARS. We are currently developing genetic tools to allow us to determine the role of various coronavirus proteins in the pathogenesis of SARS. The second project is focused on understanding how cis-acting sequences at the 5' and 3' untranslated regions (UTRs) function in replication. We have developed a novel model of structure of the 5'UTR and we are examining the role of the individual RNA stem-loop structures predicted by this model in viral replication using biochemical, cell biologic, and reverse genetic approaches.
Lepiz, Mauricio Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Anesthesiology; cardiovascular and respiratory physiology; monitoring technology - anesthesia and critical care
Levine, Gwendolyn Clinical Assistant Professor VTPB
Areas of Specialization:
Neuroscience, Neurology, Surgery, Orthopedics, Lameness
Scholarly Interests:
My scholarly interests include the use of technology in assessing normal and abnormal gait through the application of force platforms and motion capture systems. I am also interested in biomarkers in neurologic and orthopedic disease.
Levine, Jonathan Department Head, Associate Professor, & Helen McWhorter Chair in Small Animal Clinical Sciences VSCS
Areas of Specialization:
Neuroscience, Neurology
Scholarly Interests:
Spinal cord injury, in particular MR imaging and neuroprotectionNeuro-oncology
Li, Jianrong Associate Professor VIBS
Areas of Specialization:
Toxicology, Neuroscience, Cell Biology, Pathology, Imaging, Physiology
Scholarly Interests:
The central goal of our research is to understand how oligodendroglial development in the mammalian central nervous system is regulated in health and disease. Specifically, we are interested in molecular and cellular mechanisms involved in oligodendrocyte death as occurring in white matter injuries, such as multiple sclerosis and cerebral palsy. Because in most CNS diseases, multiple cell types including neurons, glial cells and vascular cells are involved via complex interactions, we investigate, at the cellular and molecular level, the role of microglia and astrocytes in modulating oligodendrocyte development, differentiation and cell death. We use a variety of methods including primary cell cultures and transgenic animals to elucidate signal transduction pathways in mediating oligodendrocyte injury. The second focus of our laboratory is to elucidate the signals that promote oligodendrocyte survival and regeneration/remyelination after injury, and to study cell-cell interactions that regulate remyelination. These studies should contribute significantly to our understanding of mechanisms of oligodendrocyte development and injury, and provide new clues for potential prevention and treatment of human white matter diseases. Our third research interest is to explore novel roles of vitamin K in the developing brain. Vitamin K is a cofactor for a single known enzyme, gamma-glutamylcarboxylase that catalyzes the posttranslational conversion of glutamic acid to gamma-carboxyglutamic acid in vitamin K-dependent proteins, such as Gas6. It prevents oxidative injury to oligodendrocytes and neurons. Several lines of evidence suggest an as yet identified role of vitamin K in the developing brain. We will use primary cell cultures and transgenic mice to investigate the physiological roles of vitamin K and the carboxylase in the developing brain.
Li, Qinglei Assistant Professor VIBS
Areas of Specialization:
Toxicology, Reproductive Biology, Cell Biology, Genetics, Oncology
Scholarly Interests:
The myometrium plays a fundamental role in a variety of female reproductive events and has a significant impact on pregnancy outcome. The structural and functional abnormalities of myometrium can lead to reproductive disorders, such as implantation failure, preterm labor, and uterine rupture, some of which are severe causes of neonatal mortality and morbidity. Despite the long-recognized importance of myometrial function in pregnancy, key signaling pathways that control myometrial development and function are not well defined. Current studies in my laboratory are to identify the role of TGFß signaling and micro-RNA in myometrial contractility and pregnancy, and define the mechanistic contributions of dysregulated TGFß signaling to the development of myometrial defects. Results of these studies will guide the design of novel therapies for myometrial dysfunction and myometrium-associated diseases. Research in this area is supported by NIH grant. My lab is also interested in understanding the SMAD signaling pathway in ovarian follicular development and ovulation. SMAD proteins can be classified into receptor-regulated SMADs (Smad1, 2, 3, 5, 8), the common SMAD (Smad4), and inhibitory SMADs (Smad6, 7). Our previous studies have identified a key role of SMAD2/3 in the maintenance of female fertility and follicular cell function. Ongoing studies in my laboratory focus on defining the ovarian function of inhibitory Smad (i.e., Smads 6 and 7) signaling and the interrelationship between inhibitory Smad signaling and Smad2/3 and/or Smad1/5/8-mediated signaling in the ovary. The third area we are interested in is to develop novel approaches to treat infertility as well as safe contraceptives for contraception. We are currently seeking highly motivated Ph.D. Candidates.
Lidbury, Jonathan Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Small animal gastroenterology and hepatology
Logan, Linda Professor VTPB
Areas of Specialization:
Infectious Disease, Public Health, Parasitology, Pathology, Medicine, Biodefense, Disaster Management, Zoo, Exotic and Wildlife Medicine
Scholarly Interests:
I have had a longstanding interest in tropical diseases of livestock. Trans-boundry diseases, vector-borne diseases and blood borne parasites have been the areas in which I have had the greatest research interest and experience. My interests more recently have focused on regulatory medicine, international livestock disease control and international agricultural trade. I have worked collaboratively with international organizations to build stronger laboratory and epi-surveillance capacity building for livestock and zoonotic diseases in Africa and the Middle East and Central Asia.
Long, Charles Associate Professor VTPP
Areas of Specialization:
Reproductive Biology, Cell Biology, Genetics
Scholarly Interests:
developmental biology, gamete and embryo physiology, embryonic stem cells, assisted reproductive technologies, animal transgenics, somatic cell nuclear transfer, epigenetics, biomedical models, disease resistance
Love, Charles Associate Professor VLCS
Areas of Specialization:
Genetics, Infectious Disease
Scholarly Interests:
Equine theriogenology. Sperm function; evaluation of fertility; and flow cytometry.
Lupiani, Blanca Professor and Associate Dean of Faculties VTPB
Areas of Specialization:
Immunology, Epidemiology, Infectious Disease, Ecology, Medicine, Biodefense, Virology, Zoo, Exotic and Wildlife Medicine
Scholarly Interests:
Research in my laboratory focuses on better understanding the ecology and evolution of avian influenza and avian paramyxoviruses. By carrying out surveillance and characterization of viruses isolated from wild bird populations from the wintering grounds of the Central Flyway (Texas Coast), we are able to better understand how these viruses are maintained in nature and how they evolve to adapt to new hosts. Molecular characterization of the viruses, together with ecological data are used for epidemiological and modeling studies. Another aspect of my research includes the study of molecular mechanisms of pathogenesis of avian influenza viruses. Using reverse genetics, specific mutations are introduced in the avian influenza virus genome in order to study their role in virus pathogenesis as well as to determine gene function. Using genomic approaches the host/virus interaction is also being studied. We are also interested in understanding molecular mechanisms of pathogenesis of Mareks disease virus, a chicken oncogenic alphaherpesvirus, and in the development of improved vaccines to control this important poultry pathogen.
Lupton, Joanne Professor - Joint Appointment VIBS
Areas of Specialization:
Scholarly Interests:
Mankin, Joseph Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Neurology; Neurosurgery; Neuroradiology
Mansell, Joanne Clinical Professor VTPB
Areas of Specialization:
Pathology, Dermatology
Scholarly Interests:
Comparative pathology with particular interest in dermatopathology. The effects of systemic disease on skin. The use of immunohistochemistry in neoplastic and inflammatory skin disease.
Martin, Gregory Assistant Research Scientist VTPP
Areas of Specialization:
Cell Biology
Scholarly Interests:
Scholarly interests include analysis of the structure and function of mammalian intracellular lipid binding proteins, e.g., sterol carrier protein-2 (SCP-2) and liver fatty acid binding protein (L-FABP).
Martin, Michael Associate Professor VLCS
Areas of Specialization:
Scholarly Interests:
Equine dentistry, parasitology, lameness, prevention medicine, lameness, dentistry.
Martinez, Elizabeth Associate Professor VSCS
Areas of Specialization:
Pharmacology
Scholarly Interests:
Anesthesiology; cardiopulmonary physiology; neuromuscular blocking agents
Mays, Glennon Clinical Associate Professor VLCS
Areas of Specialization:
Field Service (Equine), Field Service (Livestock)
Scholarly Interests:
Texas Department of Criminal Justice and livestock production medicine. Infectious disease epidemiology in livestock and equine dentistry.
McCormack, Kimberly Comparative Medicine Resident VTPB
Areas of Specialization:
Scholarly Interests:
McIntosh, Avery Associate Research Scientist VTPP
Areas of Specialization:
Scholarly Interests:
Miller, Matt Senior Professor VSCS
Areas of Specialization:
Imaging, Physiology, Cardiology
Scholarly Interests:
Comparative Cardiovascular Imaging; Animal Models of Cardiovascular Disease; Myocardial Ischemia and Reperfusion Injury; Cardiology; cardiomyopathies; interventional catheterization; vascular stenting; ventricular assist devices; catheter based therapy of vascular malformations; hemorrhagic shock, animal models of cardiac disease
Mohiuddin, Waqar Associate Research Scientist VTPP
Areas of Specialization:
Scholarly Interests:
Pulsatile Hemodynamics, Cardiovascular Biomechanics, Microvascular Rheology and Reactivity, Biomedical Device Design, GMP Manufacturing, GLP Animal Studies, Patient Specific Simulations, Finite Element Applications (FEA) in Cardiovascular Physiology
Mora, Miguel Professor - Joint Appointment VTPB
Areas of Specialization:
Scholarly Interests:
My main research area is in wildlife toxicology. My laboratory conducts basic and applied research on the effects of contaminants on animal populations, with particular emphasis on birds. We conduct field and laboratory studies to determine the effects of persistent bioaccumulative toxicants, metals and other environmental pollutants on wildlife.
Mulenga, Albert Associate Professor VTPB
Areas of Specialization:
Scholarly Interests:
Muneoka, Ken Professor VTPP
Areas of Specialization:
Scholarly Interests:
Limb/Digit Development & Regeneration, Wound Healing, Morphogenesis
Murphy, William Professor VIBS
Areas of Specialization:
Reproductive Biology, Genomics, Genetics, Zoo, Exotic and Wildlife Medicine
Scholarly Interests:
Musser, Jeffrey Clinical Associate Professor VTPB
Areas of Specialization:
Infectious Disease, Pharmacology, Microbiology, Food Animal
Scholarly Interests:
Dairy production medicine, mastitis prevention and control, and quality milk production; pharmacokinetics in exotic and food animals and drug residue prevention; vaccine investigation; viral diseases of sheep, goats, and birds.
Mwangi, Waithaka Associate Professor VTPB
Areas of Specialization:
Immunology, Infectious Disease, Biodefense, Food Animal
Scholarly Interests:
I am interested in the development of vaccines and adjuvants for the improvement of animal and human health. Many vaccine development studies conducted in in-bred mice have generated promising data. However, these outcomes have not been reproducible in humans and in livestock as well as in companion animals, the actual hosts that require protection. My current research is focused on the development of contemporary strategies for improving vaccine efficacy in outbred species. Studies are primarily directed at optimizing in vivo antigen presentation by dendritic cells following immunization. Dendritic cells are the most potent antigen presenting cells that are capable of stimulating naïve T cells to become antigen-specific effectors. In addition, I am evaluating defined dendritic cell activation factors for their potency in enhancing vaccine immunogenicity for adjuvant development. The major on-going funded efforts are directed at generating vaccines for effective protection of neonates against Bovine Viral Diarrhea Virus and for protection of swine against African swine fever virus. Development of safe and affordable immunizations strategies will enhance animal well-being and thereby improve human life.
Nabity, Mary Assistant Professor VTPB
Areas of Specialization:
Physiology, Medicine
Scholarly Interests:
Research interests involve kidney disease and urine proteomics, with a focus on the investigation of urine proteins in dogs and cats with chronic kidney disease. Our goals are to help develop and validate testing methods to improve the diagnosis and monitoring of renal disease in companion animals. Current investigations include evaluation of certain urinary proteins as early markers of renal disease and specific markers of renal disease progression. In addition, we are evaluating urine SDS-PAGE analysis in dogs and cats with various renal disorders.
Nelson, David Interim Director of the Veterinary Medical Teaching Hospital and Clinical Associate Professor VSCS
Areas of Specialization:
Surgery
Scholarly Interests:
Cardiothoracic surgery; thoracoscopic surgery; cardiopulmonary bypass; cardiovascular assist device development; effects of time varying electromagnetic fields on bone healing; anti-coagulation therapy
Nelson, Whitney Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Newell-Fugate, Annie Assistant Professor VTPP
Areas of Specialization:
Reproductive Biology, Physiology
Scholarly Interests:
Polycystic ovary syndrome (PCOS) is the most prevalent reproductive endocrine disorder in women and results in a substantial financial burden to the American healthcare system. PCOS is characterized by an/oligoovulation, polycystic ovaries, and hyperandrogenism. PCOS patients are also at risk for the development of metabolic syndrome, type 2 diabetes, and cardiovascular disease. My laboratory focuses on the effects of obesity, hyperinsulinemia, and insulin resistance on androgen steroidogenesis and the interrelationship between androgens and insulin signaling in steroidogenic tissues and adipose tissue. Using cell culture and rodent and porcine models, my research program examines the direct and indirect effects of obesity and resulting hyperandrogenemia on steroidogenesis and reproductive function in females. I also have a strong interest in wildlife and zoo animal endocrinology and reproductive physiology. In the past, I have conducted endocrine based research projects on the Pallas' Cat and African Wild Dog. My current research examines the effect of the introduction of novel pheromones versus novel animals on fecal steroid metabolite concentrations, behavior, and estrous cyclicity in captive, female Red River Hogs. I am also working with zoo-based collaborators to develop an eletroejaculation and artificial insemination protocol for this species and am using domestic swine as a model for the development of ovarian follicle culture techniques in Red River Hogs.
Norman, Keri Research Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Omran, Tawfik Clinical Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Immunopathogenesis and host immune response to infectious and noninfectious disease; signal transduction in inflammation. Specific interests include Lyme Disease (Borrelia burgdorferi) infection, pathogenesis, and vaccine studies in humans and animal models.
Pashmakova, Medora Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Patterson, Adam Clinical Assistant Professor VSCS
Areas of Specialization:
Dermatology
Scholarly Interests:
Dermatology; allergic skin disease; otitis; cutaneous infections; autoimmune skin disease.
Payne, Susan Associate Professor VTPB
Areas of Specialization:
Infectious Disease
Scholarly Interests:
Molecular aspects of viral replication, pathogenesis, and evolution. The major focus of the laboratory is the retrovirus, equine infectious anemia virus. EIAV studies include evolution of virulence during rapid virus passage, modification of cell signaling pathways mediated by viral glycoproteins, effects of proinflammatory cytokines on virus replication and disease, and detailed mapping of EIAV virulence determinants. We also study the recently discovered avian bornavirus, etiological agent of proventricular dilatation disease of parrots, in conjunction with colleagues from the Schubot center.
Perez de Leon, Adalberto Adjunct Associate Professor VTPB
Areas of Specialization:
Scholarly Interests:
Peycke, Laura Clinical Associate Professor VSCS
Areas of Specialization:
Scholarly Interests:
Soft-tissue surgery; gastrodilatative volvulus
Phillips, Timothy Distinguished Professor VIBS
Areas of Specialization:
Toxicology, Food Safety
Scholarly Interests:
food safety; molecular toxicology; elucidation of fundamental chemical mechanisms of toxic action/interaction of food-borne carcinogens; mutagens; and developmental toxicants; and development of methods to detect and detoxify foodborne and environmental toxins.
Pine, Michelle Clinical Assistant Professor VIBS
Areas of Specialization:
Toxicology, Environmental Health, Neurology
Scholarly Interests:
neurotoxicology; neuroendocrinology; the mechanism underlying the effects of pesticides (particularly synthetic pyrethroids) on neurodevelopment.
Pinedo, Pablo Assistant Professor-Joint Appointment VTPB
Areas of Specialization:
Epidemiology, Genomics, Genetics, Infectious Disease, Food Animal
Scholarly Interests:
My interest centers in population medicine and includes the analysis of multiple factors that affect health, production, and longevity of dairy and beef cattle. My research focuses on epidemiologic approaches to understanding disease and production dynamics; genomic selection tools for improved health, fertility, and productive life; and pre-harvest ecology of foodborne pathogens.
Pool, Roy Clinical Professor VTPB
Areas of Specialization:
Oncology, Orthopedics
Scholarly Interests:
Diagnostic orthopedic pathology and oncology
Porter, Brian Clinical Associate Professor VTPB
Areas of Specialization:
Neuroscience, Environmental Health, Pathology, Anatomic Pathology
Scholarly Interests:
Comparative neuropathology; canine gliomas and canine spinal trauma as models for the human conditions; wildlife disease and environmental conservation
Porter, Weston Associate Professor-Joint Appointment VIBS
Areas of Specialization:
Toxicology, Cell Biology, Environmental Health, Genetics, Oncology
Scholarly Interests:
My laboratory is interested in determining the role of factors in normal development and how disruption of these pathways results in associated pathologies.
Posey, Dan Director of Special Programs and Clinical Associate Professor DCVM
Areas of Specialization:
Scholarly Interests:
Beef cattle production medicine; issues associated with sustainable agriculture; instruction and teaching of non-technical competencies, and outcome assessment in teaching.
Puschett, Jules Research Professor VTPB
Areas of Specialization:
Genomics, Genetics, Biodefense
Scholarly Interests:
Preeclampsia, Traumatic Brain Injury, Acute myocardial Infarction, Cardiotonic Steroids (Cardiac Glycosides), Acute Kidney Injury, Acute Respiratory Distress Syndrome
Qian, Yongchang Research Assistant Professor VIBS
Areas of Specialization:
Toxicology, Neuroscience, Cell Biology
Scholarly Interests:
The research interests include astroglial cell biology and heavy metal neurotoxicity. The studies have identified that Pb deposit in astrocytes competitively with copper (Cu) binds to heavy metal binding (HMB) domain of ATP7A, a Cu-transporting ATPase that contributes to Cu release, leading to Cu accumulation intracellularly and the promotion of reactive oxygen species (ROS) production that both have been involved in neurodegenerative diseases including Alzheimer’s disease and amyotrophic lateral sclerosis. The studies have also identified a 78 kD glucose-regulated protein (GRP78), also named as HSPA5 or BiP, as one of Pb targets. GRP78 is an endoplasmic reticulum-resident molecular chaperone functioning in protein folding, assembly and trafficking in posttranslational quality control and also plays a role in protection against cytotoxicity and apoptosis induced by environmental insults. Emerging evidence indicates that the protein is involved in cancers including breast cancers, lung cancers, and others and neurodegenerative disorders including Alzheimer's disease. The studies demonstrate that Pb directly binds to GRP78 and the binding plays a “double-edged sword” role because it protects the cells from the toxicity of free Pb ions but also reduces protein secretion (e.g. IL-6) and Cu release from astrocytes. Current interests are focused on functions of GRP78 in Cu homeostasis and glucose utilization of the central nervous system that both are involved in neurodegenerative disorders and cancers.
Quick, Christopher Associate Professor VTPP
Areas of Specialization:
Physiology
Scholarly Interests:
Insterstitial fluid balance; pulsatile hemodynamics; coordination of adaptation in vascular networks; undergraduate research-intensive communities
Ramadoss, Jay Assistant Professor VTPP
Areas of Specialization:
Reproductive Biology, Physiology
Scholarly Interests:
Perinatal biology, pregnancy and fetal development, alcohol teratology, reproductive endocrinology, developmental neuroanatomy, vascular biology, obstetric medicine, proteomics and genomics, Developmental Origins of Health and Disease
Raudsepp, Terje Associate Professor VIBS
Areas of Specialization:
Genetics
Scholarly Interests:
Comparative genomics and molecular cytogenetics of animals, birds and other vertebrates organization, function and evolution of sex chromosomes; equine genomics - genomics of genetic diseases and disorders of sexual development and reproduction; alpaca and camelid genomics.
Rech, Raquel Clinical Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Diagnostic and comparative pathology with emphasis in Neuropathology; Pathogenesis of disease in cattle and pigs Diseases of wild boars
Reddy, Sanjay Professor VTPB
Areas of Specialization:
Infectious Disease, Oncology, Microbiology, Virology
Scholarly Interests:
The long-term goal of my laboratory is to understand the molecular basis of pathogenesis of Marek’s disease virus (MDV), a potent oncogenic herpesvirus that causes T-cell tumors in chickens. MDV codes for a protein (Meq), which shares significant resemblance with the Jun/Fos family of transcriptional factors. We have shown that this gene plays a critical role in latency and transformation of T-lymphocytes. Understanding the basic mechanism of viral pathogenesis will aid in the development of improved vaccine. We are also interested in other important poultry disease like avian influenza.
Rice-Ficht, Allison Professor-Joint Appointment VTPB
Areas of Specialization:
Scholarly Interests:
Microencapsulation research and vaccine delivery vehicles; use of proteins and protein composites in controlled release for vaccines and pharmaceuticals. Mechanisms of protein folding directed by alpha crystallins and other small heat shock proteins. Mechanisms of genetic polymorphism and diversity among Mycobacterium avium paratuberculosis isolates; innate immunity and host gene expression in response to paratuberculosis infection.
Rijnkels, Monique Research Assistant Professor VIBS
Areas of Specialization:
Scholarly Interests:
Rivera, Gonzalo Assistant Professor VTPB
Areas of Specialization:
Cell Biology, Imaging, Oncology, Physiology
Scholarly Interests:
My laboratory is interested in the role played by cytoskeletal remodeling in development and disease, particularly, angiogenesis and tumor progression and invasion. The long-term goal of our research is to understand how extracellular signals that alter tyrosine phosphorylation and the metabolism of inositol phospholipids modulate actin dynamics and cell motility. Areas of interest include the biogenesis of actin-based structures of invasion, intracellular trafficking, and three-dimensional tissue morphogenesis in vitro. Our research employs a combination of molecular genetics, cell biology, proteomics, and high-resolution optical imaging.
Rodrigues Hoffmann, Aline Assistant Professor VTPB
Areas of Specialization:
Toxicology, Infectious Disease, Pathology, Microbiology, Virology, Dermatology, Anatomic Pathology
Scholarly Interests:
I have broad experience in Veterinary Pathology pursuing macroscopic evaluation, histological examination and immunohistochemistry in tissues from different animal species, including small animals, large animals, laboratory animals, and exotic species. My particular area of interest is in Dermatopathology, providing diagnostic service, and working closely with our dermatologists, and with the dermatologists and clinicians from private clinics throughout the country that submit samples to our Dermatopathology Specialty Service. I provide diagnostic service and consultation to the Veterinary Medical Teaching Hospital at TAMU, and support collaborative research studies. My research focuses on investigating how the skin microbiome in animals could play a role/contribute to development of skin lesions. Our research group has shown that the skin in dogs is colonized by diverse and rich microbial communities, and that healthy dogs have a more diverse skin microbiome when compared to allergic dogs.
Rogers, Kenita Associate Dean for Professional Programs DCVM
Areas of Specialization:
Oncology, Education
Scholarly Interests:
DVM student curriculum
Rogovskyy, Artem Clinical Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Romano, Juan Associate Professor VLCS
Areas of Specialization:
Reproductive Biology, Field Service (Livestock), Production Medicine, Food Animal
Scholarly Interests:
Reproduction in Large and Small ruminants. Assisted Reproductive Technologies. Reproductive management in ruminants.
Roussel, Allen Professor & Department Head VLCS
Areas of Specialization:
Infectious Disease, Medicine, Food Animal
Scholarly Interests:
Food animal medicine, Johne's disease, internal medicine and meat goats. Paratuberculosis, clinical laboratory diagnostic testing and interpretation, gastrointestinal motility of domestic animals, fluid and electrolyte balance in large animals.
Roy Sarkar, Tapasree Research Assistant Professor VIBS
Areas of Specialization:
Cell Biology, Oncology
Scholarly Interests:
The focus of my work is to investigate the role of exosomes in cancer progression and metastasis.
Ruoff, Catherine Clinical Assistant Professor VLCS
Areas of Specialization:
Scholarly Interests:
Radiology - small and large animal Research: Diagnostic imaging - radiography ultrasound MRI, CT, nuclear medicine and musculoskeletal imaging
Ruoff, Lynn Clinical Associate Professor VIBS
Areas of Specialization:
Anatomy
Scholarly Interests:
teaching gross anatomy in the undergraduate and professional curriculums
Russell, Karen Professor VTPB
Areas of Specialization:
Scholarly Interests:
Platelet pathophysiology and the interaction of platelets with infectious agents, with an emphasis on the thrombocytopenia associated with Equine Infectious Anemia Virus. Investigation of platelet activation markers in veterinary species. Investigation of total and free (ionized) magnesium concentrations in veterinary species.
Russell, Leon Senior Professor VIBS
Areas of Specialization:
Epidemiology, Food Safety, Public Health
Scholarly Interests:
epidemiology; medical mycology; zoonotic diseases (rabies); food toxicology.
Rusyn, Ivan Professor VIBS
Areas of Specialization:
Toxicology
Scholarly Interests:
Safe, Stephen Distinguished Professor VTPP
Areas of Specialization:
Toxicology, Environmental Health, Oncology, Pharmacology
Scholarly Interests:
Toxicology and molecular biology of estrogenic and antiestrogenic compounds; molecular mechanisms of estrogen receptor and Ah receptor action and their crosstalk in breast cancer; NR4A1 and Sp proteins as drug targets; long non-coding RNAs
Samollow, Paul Professor VIBS
Areas of Specialization:
Genomics, Genetics
Scholarly Interests:
omparative functional genomics and genome evolution in vertebrates; structural organization of genetic material and its relationship to patterns of gene regulation and expression within and among species. Epigenetics of meiotic recombination; patterns and epigenetic determinants of sexual dimorphism in meiotic recombination rates and chromosomal distributions. Population genomics: genetic and ecological processes that influence the distribution of genetic diversity within and among populations in nature; population structure, isolation, and speciation. QTL mapping: linkage mapping to detect genes that influence physiologic and health-related traits. Research in my laboratory focuses primarily on the genome of the gray, short-tailed opossum, Monodelphis domestica, the world's primary laboratory marsupial model for genomic, biomedical, and evolutionary research. We also study isolated desert populations of pupfishes of the genus Cyprinodon in west Texas.nature, and their roles in promoting population structuring, isolation, and speciation. QTL mapping: linkage mapping to detect genes that influence physiologic and health-related traits. Research in my laboratory focuses primarily on the genome of the gray, short-tailed opossum, Monodelphis domestica, the world's primary laboratory marsupial model for genomic, biomedical, and evolutionary research. We also study isolated desert populations of pupfishes of the genus Cyprinodon in west Texas.
Saunders, Ashley Associate Professor VSCS
Areas of Specialization:
Cardiology
Scholarly Interests:
Congenital heart disease; interventional cardiology; transesophageal echocardiography; heart failure management; Advanced imaging
Saunders, W. Brian Assistant Professor VSCS
Areas of Specialization:
Cell Biology, Surgery, Orthopedics
Scholarly Interests:
Clinical interests: total joint replacement, arthroscopy, minimally invasive fracture repair, correction of angular limb deformities. Research interests: cell-matrix interactions, matrix metalloproteinases (MMPs), canine and human adult mesenchymal stem cells (MSCs).
Scallan, Elizabeth Lecturer VSCS
Areas of Specialization:
Scholarly Interests:
Schmitz, David Visiting Associate Professor VLCS
Areas of Specialization:
Imaging, Medicine, Diagnostic Imaging
Scholarly Interests:
Equine internal medicine and diagnostic ultrasound.
Schroeder, Friedhelm Professor VTPP
Areas of Specialization:
Physiology
Scholarly Interests:
Intracellular lipid transfer proteins; lipid metabolism; multiphoton imaging of intracellular lipid transport and targeting in living cells and tissues of gene targeted animals.
Scott, Erin Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Scott, H. Morgan Professor VTPB
Areas of Specialization:
Scholarly Interests:
Dr. Scott is a veterinary epidemiologist who studies antibiotic resistance mechanisms among foodborne pathogens and their relation with the use of antibiotics in food animals. This is a topic of increasing concern, especially where limited field data have not previously been available. In addition, Dr. Scott works to improve public health and animal well-being and to sustain healthy ecosystems by using risk analysis and epidemiologic studies to minimize the impacts of infectious hazards. Dr. Scott works closely with the livestock industry and serves as an advisor for the World Health Organization.
Seabury, Christopher Associate Professor VTPB
Areas of Specialization:
Genomics, Genetics, Infectious Disease
Scholarly Interests:
Mammalian molecular genetics, genomics, and population genetics; animal disease genomics; utilization of population and quantitative genetics to elucidate host loci and relevant variation influencing differential susceptibility to disease, adaptability, and feed efficiency; next generation sequencing and de novo genome assembly as a mechanism to enable novel research programs in non-model mammalian and avian species of interest.
Shaw, Sarah Lecturer VLCS
Areas of Specialization:
Scholarly Interests:
Specialty interests: Equine infectious disease, neurology, neonatology, lameness diagnostics and neuromuscular disease. Research interests: Rhodococcus equi, ultrasound and advanced imaging
Shi, Liheng Research Assistant Professor VIBS
Areas of Specialization:
Neuroscience, Pharmacology, Physiology, Cardiology
Scholarly Interests:
Simon, Bradley Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Singh, Neetu Post Doc VTPP
Areas of Specialization:
Scholarly Interests:
Skow, Loren Professor VIBS
Areas of Specialization:
Immunology, Genomics, Genetics, Infectious Disease
Scholarly Interests:
Comparative genomics of mammals with emphasis on organization and evolution of the mammalian genome; molecular analysis of the major histocompatibility complex of hoofed animals; genetic mechanisms of inherent resistance to infectious diseases.
Smith, Roger Professor and Interim Head VTPB
Areas of Specialization:
Immunology
Scholarly Interests:
Application of flow cytometry to study of animal disease and clinical veterinary medicine; core flow cytometry laboratory.
Snowden, Karen Professor VTPB
Areas of Specialization:
Infectious Disease, Parasitology, Education
Scholarly Interests:
Parasites of public health importance, host-parasite interactions, development of animal models for the study of parasitologic diseases and treatments, and development of molecular and immunologic methods for parasitologic diagnosis.
Spaulding, Kathy Clinical Professor VLCS
Areas of Specialization:
Imaging
Scholarly Interests:
Radiology, abdominal diagnostic ultrasound.
Sreevalsan, Sandeep PostDoctoral Research Assoc VTPP
Areas of Specialization:
Scholarly Interests:
Srivastava, Vinod Research Associate Professor VIBS
Areas of Specialization:
Toxicology, Reproductive Biology, Cell Biology
Scholarly Interests:
Stallone, John Professor and Interim Head VTPP
Areas of Specialization:
Reproductive Biology, Pharmacology, Physiology
Scholarly Interests:
Vascular physiology and pharmacology, especially sex differences in vascular function, blood pressure and hypertension. The roles of the gonadal steroids (androgens and estrogens) in the regulation of vascular function, and endothelium-vascular smooth muscle interactions.
Steiner, Jörg Professor - Joint Appointment VSCS
Areas of Specialization:
Medicine
Scholarly Interests:
Small animal and comparative gastroenterology
Stewart, Randolph Clinical Professor VTPP
Areas of Specialization:
Physiology
Scholarly Interests:
cardiovascular physiology; lymphatic function; microvascular physiology; interstitial and cavity fluid balance
Stickney, Mark Clinical Associate Professor VSCS
Areas of Specialization:
Scholarly Interests:
Elective surgery; pain management; mammary cancer; electrosurgery and laparoscopic surgery
Stoica, George Professor VTPB
Areas of Specialization:
Immunology, Toxicology, Neuroscience, Cell Biology, Genetics, Pathology, Imaging, Oncology, Virology, Laboratory Animal Medicine
Scholarly Interests:
Mechanism(s) of retro viral-induced neurodegeneration. Pathogenesis of brain and bone metastases of mammary gland tumors; application of flow cytometry in the study of tumors; lectin and immunohistochemistry; chemical carcinogenesis; animal models for retro virus-induced neoplasia. Genetic alterations in tumors of the nervous system, dog animal model. Investigating the mechanism of alpha-synuclein in neurodegeneration in a rat animal model. Application of non-invasive technologies in biomedical science. Use of molecular markers in non-invasive optical imaging technologies.
Suchodolski, Jan Clinical Associate Professor VSCS
Areas of Specialization:
Immunology, Genomics, Infectious Disease, Medicine, Microbiology
Scholarly Interests:
Gastroenterology, Microbiome, Microbiota, Metagenomics, Metabolomics, Probiotics
Taylor, Doris Adjunct Professor VTPP
Areas of Specialization:
Scholarly Interests:
Thieman Mankin, Kelley Assistant Professor VSCS
Areas of Specialization:
Surgery
Scholarly Interests:
Soft Tissue SurgerySurgical site infection prevention and control
Thompson, James Professor VLCS
Areas of Specialization:
Environmental Health
Scholarly Interests:
Food animal reproduction. Environmental health, reproduction and cancer.
Threadgill, David Professor and Director, Whole Systems Genomic Initiative VTPB
Areas of Specialization:
Scholarly Interests:
My laboratory uses the mouse as an experimental genetic model to investigate factors that contribute to inter-individual differences in health and disease. Our current research activities include the identification and functional characterization of alleles contributing to cancer susceptibility, the function of the Erbb gene family in development and disease, and the role of genetic variation in response to environmental stimuli. To support these investigations, we also are developing new genetic tools to support mammalian systems genetic approaches to phenotypes with complex genetic and environmental etiologies. Cancer genetics: We are focusing on colorectal and breast cancer to identify environmental factors and genetic polymorphisms contributing to differential susceptibility to the development and progression of cancer. We are also developing approaches to exploit these factors to prevent or delay cancer as well as to identify new therapies. Epidermal growth factor receptor (Egfr): We are using mouse models with genetically engineered or spontaneous mutations to elucidate the biological role of Egfr and other member of the Erbb gene family in vivo. These studies have lead to new insights into the role of these genes in neuronal survival and behavior, obesity, cancer and cardiovascular disease. We are currently performing mechanistic studies to identify how the Erbb genes contribute to normal and abnormal phenotypes. Genetics of environmental response: Just as individuals differ in their genetic constitution and disease susceptibility, they also differ in their responses to exogenous stimuli. We are using mouse models to investigate responses to environmental factors like the enteric flora of the gastrointestinal tract and diet and toxicants like dioxin and trichloroethane. The goal of these studies is to identify how individual responses to environmental factors leads to differential disease susceptibilities. Systems genetics resources: We are leading a large international effort to develop and exploit a new mouse genetic resources that will support the integration of genetics into systems biological analyses at the whole animal level. These efforts are based upon the Collaborative Cross, which is a unique recombinant inbred population of mice that have randomly assorted the genetic polymorphisms present in the eight founder inbred strains.
Threadgill, Deborah Assistant Professor VTPB
Areas of Specialization:
Scholarly Interests:
Tian, Yanan Associate Professor VTPP
Areas of Specialization:
Immunology, Cell Biology, Environmental Health, Imaging, Pharmacology, Physiology, Microbiology, Dermatology
Scholarly Interests:
transcriptional control of the Ah receptor-regulated gene expression. Interaction between the Ah receptor and NF-kB signal transduction pathways.
Tiffany-Castiglioni, Evelyn Associate Dean for Undergraduate Education, Professor and Department Head VIBS
Areas of Specialization:
Toxicology, Neuroscience, Cell Biology
Scholarly Interests:
My primary research interests are neurotoxicology and in vitro toxicology, particularly the mechanisms by which brain cells called astrocytes handle toxic metals.
Tizard, Ian Distinguished Professor VTPB
Areas of Specialization:
Immunology, Neuroscience, Genomics, Infectious Disease, Virology, Zoo, Exotic and Wildlife Medicine, Avian Medicine
Scholarly Interests:
Immunology with an emphasis on innovative vaccine technology and on the immunology of domestic mammals.Avian diseases with an emphasis on diseases of psittacinesPaleovirology,Genomics with an emphasis on whole avian genomes.The intestinal microbiome and its role in immunity.
Vallone, Lucien Clinical Assistant Professor VSCS
Areas of Specialization:
Scholarly Interests:
Varner, Dickson Professor & Pin Oak Stud Chair of Stallion Reproductive Studies VLCS
Areas of Specialization:
Reproductive Biology
Scholarly Interests:
Equine theriogenology. Fertility probes for stallions; in-vitro preservation of equine spermatozoa; capacitation of equine spermatozoa; assisted reproductive techniques; and subfertility in stallions.
Venkatraj, Vijayanagaram Clinical Associate Professor VIBS
Areas of Specialization:
Toxicology, Neuroscience, Cell Biology, Genomics, Genetics, Oncology, Neurology, Medicine, Education
Scholarly Interests:
Our laboratory is interested in understanding the altered signaling pathways in breast and other cancers using multivariate boolean modeling and testing. We have taken a Systems Biology Approach to understand cancer, and work closely with Dr Aniruddha Datta's Genomic Signalling laboratory in Electrical and Computer Engineering here at Texas A & M Engineering School.
Waghela, Surya Clinical Assistant Professor VTPB
Areas of Specialization:
Immunology, Infectious Disease, Parasitology, Microbiology
Scholarly Interests:
Immunoparasitology; infectious diseases; emerging and foreign animal diseases, especially tick-borne diseases; use molecular biology techniques to develop better diagnostic tests and immunogens for infectious diseases in ruminants of tropical areas of the world; development of biopharmaceuticals and biosensors; engineer recombinant antibodies for diagnosis and prevention of infectious diseases.
Waltz, Micah Lecturer VIBS
Areas of Specialization:
Scholarly Interests:
Washburn, Kevin Associate Professor VLCS
Areas of Specialization:
Scholarly Interests:
Food Animal Medicine & Surgery. Developing and investigating the disposition of extra-label antimicrobials in small ruminants; pharmacokinetics of respiratory antimicrobials; comparison of different treatment modalities for small ruminant caseous lymphadenitis; the value of the HI test for diagnosis of small ruminants with caseous lymphadenitis; diagnosis of transmission of CAEV via colostrum; and antemortem diagnosis of malignant lymphoma in cattle. Investigating infection of swine with Mycobacterium avium subspecies paratuberculosis in attempts to create an animal model for human inflammatory bowel disease.
Washburn, Shannon Clinical Assistant Professor VTPP
Areas of Specialization:
Food Safety, Reproductive Biology, Genomics, Genetics, Science/Tech Journalism, Cardiology, Biodefense, Anesthesia
Scholarly Interests:
Fetal Alcohol Spectrum Disorders (FASD) mechanisms; neuroimaging, biomarkers and nutritional interventions for FASD; clinical medicine; pharmacology; pathophysiology; teaching methods and learning in the professional program
Wasser, Jeremy Associate Professor VTPP
Areas of Specialization:
Physiology, Education
Scholarly Interests:
My current research focuses on undergraduate and medical (human and veterinary) education. I am focusing on developing novel active teaching methodologies that involve students in their own biomedical educations and turn them into active and creative life-long learners. I am particularly interested in international education for both undergraduates and veterinary students and, over the last 10 years, have devoted significant effort to the development and execution of study abroad and international student exchange programs.
Watkins, Jeffrey Professor VLCS
Areas of Specialization:
Surgery, Orthopedics, Lameness
Scholarly Interests:
Orthopedic Surgery. Equine fracture management including: intramedullary interlocking nail fixation; fracture biomechanics; biomaterials; implant design and testing; arthrodesis techniques; management of infection; and orthopedic applications of stem cell therapy.
Watts, Ashlee Assistant Professor VLCS
Areas of Specialization:
Medicine, Surgery, Orthopedics, Lameness
Scholarly Interests:
Equine Orthopedics. Research Interests: Comparative Orthopedics; cartilage and tendon repair; stem cell biology; stem cell therapy; gene therapy; osteoarthritis prevention; regenerative medicine
Weeks, Brad Professor VTPB
Areas of Specialization:
Scholarly Interests:
Diagnostic anatomic pathology; collaborative research of inflammatory and neoplastic gastrointestinal disease, and cardiovascular disease. Veterinary medical education, particularly general pathology.
Wells, Gregg Associate Professor- Joint Appointment VTPB
Areas of Specialization:
Neuroscience, Pathology, Anatomic Pathology
Scholarly Interests:
Role of protein structure in health and disease, particularly in neurological disease. 1) Structure and function of neurotransmitter-gated ion channels: nicotinic acetylcholine, serotonin 5HT3, glycine, and GABAA receptors from eukaryotes and prokaryotes. 2) Interpreting electrophysiologic properties of ligand gated ion channels, including cyclic nucleotide gated channels, in terms of structure and thermodynamics. 3) Computational modeling of electrophysiologic function of cochlear hair cells. 4) Comparative genomics of electric fish. 5) Clinical neuropathology.
Welsh Jr., Thomas Professor - Joint Appointment VIBS
Areas of Specialization:
Immunology, Reproductive Biology, Physiology
Scholarly Interests:
Welsh, C. Jane Professor (Joint Appointment) and Assistant Dean for Graduate Studies VIBS
Areas of Specialization:
Immunology, Neuroscience, Cell Biology, Genetics, Infectious Disease, Neurology, Microbiology, Virology
Scholarly Interests:
Neuroimmunology, neurovirology, psychoneuroimmunology, viral infections of the central nervous system, animal models of: multiple sclerosis, epilespy; autoimmune diseases, effects of stress on viral pathogenesis, cerebrovascular endothelial cells and blood-brain barrier function, therapies for multiple sclerosis, factors involved in susceptibility to multiple sclerosis.
Westhusin, Mark Professor VTPP
Areas of Specialization:
Reproductive Biology, Cell Biology, Genomics, Genetics, Physiology, Biodefense
Scholarly Interests:
gamete physiology; developmental biology; embryo physiology; assisted reproductive techniques; in vitro fertilization; embryo transfer. Cloning animals by nuclear transplantation, genetic engineering in animals, epigenetics and control of gene expression, RNA interference.
Willard, Mike Professor VSCS
Areas of Specialization:
Infectious Disease, Pathology, Medicine
Scholarly Interests:
Gastroenterology, hepatology, pancreatology, endoscopy
Wilson-Robles, Heather Associate Professor & Dr. Fred A. and Vola N. Palmer Chair in Comparative Oncology VSCS
Areas of Specialization:
Cell Biology, Oncology
Scholarly Interests:
I have two main areas of scholarly interest. The first is bench top research focusing on identification and characterization of tumor initiating cells in solid tumors with a one health perspective (i.e. tumors similarities and treatment implications across species). The second focus of my research involves clinical trials in client owned dogs with spontaneously developing tumors as a basis for informing human clinical trials. Much of this research also has a one health implication designed to streamline drugs or therapies for human trials decreasing the cost of drug approval while improving therapeutic options for canines afflicted with cancer.
Womack, James Distinguished Professor VTPB
Areas of Specialization:
Genomics, Genetics, Infectious Disease, Biodefense
Scholarly Interests:
Comparative mammalian genomics with emphasis on bovids and laboratory animals. Study of evolution of gene families and genomic variation underlying disease resistance. Investigation of genetic mechanisms in innate immunity with focus on livestock, select agents, and agricultural biosecurity.
Yeoman, Michelle Lecturer VIBS
Areas of Specialization:
Scholarly Interests:
Zhou, Beiyan Assistant Professor VTPP
Areas of Specialization:
Immunology, Toxicology, Reproductive Biology, Cell Biology, Genomics, Genetics, Oncology, Physiology, Medicine, Cardiology
Scholarly Interests:
The long-term goal of our lab is to understand the systemic network governed by epigenetic factors in stem cells and their progenies. We want to dissect the mechanisms that makes a stem cell a stem cell (cell identity), maintains as a stem cell (stemness) or goes to a specific lineage (cell fate determination). We adopted well established systems to dissect the interactive network controlling adult stem cells and cancer stem cells, and differentiated blood cells functions in the context of diabetes from the angle of non-coding RNAs. Two major direction that we are currently interested in are: a.Mechanism of microRNAs in immune cell function, including macrophage activation and obesity induced cardiac vascular diseases and metabolic syndroms. b.The regulation of microRNAs in hematopoietic stem cell function and leukemic transformation
Zhu, Guan Professor VTPB
Areas of Specialization:
Genomics, Infectious Disease, Parasitology, Microbiology, Biodefense
Scholarly Interests:
Our laboratory conducts translational research with an ultimate goal to discover new anti-parasitic therapeutics by targeting metabolic enzymes and other molecules critical or essential to the parasite infection, survival and development, such as those involved in the lipid and energy metabolisms and interacting with host cells in Cryptosporidium and other protozoan parasites. Other research areas include functional genomics and molecular evolution of apicomplexan parasites, and parasitic diseases important to the conservation of wild animals. Please also see additional lab information at http://www.guanzhulab.com .
Zoran, Deb Professor VSCS
Areas of Specialization:
Medicine, Disaster Management
Scholarly Interests:
Nutrition - especially related to feline health, obesity, GI diseases and exercise physiology of working caninesEducation - especially related to development of curricula for emergency preparedness and response, use of simulations in the teaching of disaster response