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Luc Berghman

Associate Professor-Joint Appointment

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Phone: (979) 845-2994

Mailstop: 2472

Department: VTPB

Photo of Berghman, Luc


  • Ph.D. Zoology , University of Leuven, Belgium 1988
  • M.Sc. Zoology, University of Leuven, Belgium 1982

Scholarly Interests

Major goals of my program are (1) to acquire fundamental new knowledge of the avian immune system, especially antigen presentation and (2) to apply this new knowledge toward the development of novel immuno-biotechnological tools, such as vaccines, immunoassays and diagnostics. Basic avian immune studies include the study of cellular and humoral interactions, especially those involving the chicken professional antigen-presenting cells (APC)s (macrophages, dendritic cells and B-cells). Immuno-biotechnological applications include the development of monoclonal antibodies (a routine procedure and hallmark of our lab), polyclonal antibodies (incl. in chicken egg yolk), and recombinant antibodies for diagnostic, prophylactic and therapeutic purposes. Current projects feature the development of antibody-guided 'smart' vaccines, and the development of immunodiagnostic and analytical tools for the detection of a wide variety of molecules and microorganisms.


A single-chain fragment variable recombinant antibody against F5 fimbria of enterotoxigenic Escherichia coli inhibits agglutination of horse red blood cells induced by F5 protein.
Bhaskaran S, Jay CM, Berghman LR, Wagner GG, Waghela SD
Vet Res Commun. 2005 29(6):463-76.
In situ detection and quantification of bursa of fabricius cellular proliferation or apoptosis in normal or steroid-treated neonatal chicks.
Higgins SE, Berghman LR, Moore RW, Caldwell DJ, Caldwell DY, Tizard I, Hargis BM
Poult Sci. 2002 81(8):1136-41.

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