Skip Navigation

Yanan Tian

Associate Professor

Send Email

Phone: (979) 458-3599

Mailstop: 4466

Department: VTPP

Photo of Tian, Yanan


  • Ph.D. Biochemistry and Microbiology , Rutgers University 1993
  • MS Plant Pathology, South China Agriculture University 1985
  • Bachelor Plant Protection, South China Agriculture College 1982

Scholarly Interests

Transcriptional control of the Ah receptor-regulated gene expression. Interaction between the Ah receptor and NF-kB signal transduction pathways. lncRNAs and their role in regulation of gene expression


Epigenetic regulation of pregnane X receptor activity.
Yanan Tian
Drug Metab Rev.
Interaction between Microbes and Host Intestinal Health: Modulation by Dietary Nutrients and Gut-Brain-Endocrine-Immune Axis
Chen J, Li Y, Tian Y, Huang C, Li D, Zhong Q, Ma X
Curr Protein Pept Sci.
Ah receptor and NF-kappaB interplay on the stage of epigenome.
Tian Y
Biochem Pharmacol. 77(4):670-80.
Ah receptor and NF-kappaB interactions: mechanisms and physiological implications.
Tian Y, Rabson AB, Gallo MA
Chem Biol Interact. 141: 97-115.
Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells.
Ouyang N, Ke S, Eagleton N, Xie Y, Chen G, Laffins B, Yao H, Zhou B, Tian Y
Br J Cancer. 102(12):1753-61.
Histopathology and the detection of avian bornavirus in the nervous system of birds diagnosed with proventricular dilatation disease.
Ouyang N, Storts R, Tian Y, Wigle W, Villanueva I, Mirhosseini N, Payne S, Gray P, Tizard I
Avian Pathol. 38(5):393-401.
Epigenetic regulation of transcriptional activity of pregnane X receptor by protein arginine methyltransferase 1.
Xie Y, Ke S, Ouyang N, He J, Xie W, Bedford MT, Tian Y
J Biol Chem. 284(14):9199-205.
Pregnane X receptor protects HepG2 cells from BaP-induced DNA damage.
Naspinski C, Gu X, Zhou GD, Mertens-Talcott SU, Donnelly KC, Tian Y
Toxicol Sci. 104(1):67-73.
Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents.
Gu X, Ke S, Liu D, Sheng T, Thomas PE, Rabson AB, Gallo MA, Xie W, Tian Y
J Biol Chem. 281(26):17882-9.
Interactions between the aryl hydrocarbon receptor and P-TEFb. Sequential recruitment of transcription factors and differential phosphorylation of C-terminal domain of RNA polymerase II at cyp1a1 promoter.
Tian Y, Ke S, Chen M, Sheng T
J Biol Chem. 278(45):44041-8.
Pregnane X Receptor as the "Sensor and Effector" in Regulating Epigenome.
Ma X, Chen J, Tian Y
J Cell Physiol.
The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor.
Liu MJ, Takahashi Y, Wada T, He J, Gao J, Tian Y, Li S, Xie W
Mol Pharmacol. 76(3):604-11.
Epistasis and decanalization shape gene expression variability in humans via distinct modes of action
Gang Wang, Ence Yang, Jizhou Yang, Beiyan Zhou, Yanan Tian, James J Cai
Hum Mol Genet. . [Epub ahead of print].
T-2 toxin regulates steroid hormone secretion of rat ovarian granulosa cells through cAMP-PKA pathway.
Wu J, Tu D, Yuan LY, Yi JE, Tian Y
Tox Lett.

Request Update