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Michael Golding

Assistant Professor

Curriculum Vitae

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Phone: (979) 862-1332

Mailstop: 4466

Department: VTPP

Photo of Golding, Michael

Web Presence

Education

  • Postdoc Epigenetics, Childrens Health Research Institute - UWO 2009
  • Postdoc RNA Interference, Cold Spring Harbor Labs 2006
  • Ph.D. Veterinary Physiology, Texas A&M University 2003
  • BSc. Molecular Genetics, University of Western Ontario 2000

Job Functions

  • Research into Fetal Alcohol Syndrome as well as Teaching Undergraduate and Graduate Fetal Physiology

Scholarly Interests

Fetal Physiology, Epigenetic Programming and Fetal Alcohol Syndrome.

Publications

Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine development.
Golding MC, Williamson GL, Stroud TK, Westhusin ME, Long CR.
Mol Reprod Dev. 2011 May; 78(5):306-17.
PMID: 21480430 [PubMed - indexed for MEDLINE]
Production of transgenic calves expressing an shRNA targeting myostatin.
Tessanne K, Golding MC, Long CR, Peoples MD, Hannon G, Westhusin ME.
Mol Reprod Dev. 2011 Nov; .
PMID: 22139943 [PubMed - as supplied by publisher]
Selection of stable reference genes for quantitative rt-PCR comparisons of mouse embryonic and extra-embryonic stem cells.
Veazey KJ, Golding MC.
PLoS One. 2011 ; 6(11):e27592.
PMID: 22102912 [PubMed - in process]
Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells.
Golding MC, Magri LS, Zhang L, Lalone SA, Higgins MJ, Mann MR.
Development. 2011 Sep; 138(17):3667-78.
PMID: 21775415 [PubMed - indexed for MEDLINE]
A bidirectional promoter architecture enhances lentiviral transgenesis in embryonic and extraembryonic stem cells.
Golding MC, Mann MR.
Gene Ther. 2011 Aug; 18(8):817-26.
PMID: 21390068 [PubMed - indexed for MEDLINE]
Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine development.
Golding MC, Williamson GL, Stroud TK, Westhusin ME, Long CR.
Mol Reprod Dev. 2011 May; 78(5):306-17.
PMID: 21480430 [PubMed - in process]
Applications of RNA interference-based gene silencing in animal agriculture.
Long CR, Tessanne KJ, Golding MC.
Reprod Fertil Dev. 2010 ; 22(1):47-58.
PMID: 20003845 [PubMed - indexed for MEDLINE]
Multiple epigenetic modifiers induce aggressive viral extinction in extraembryonic endoderm stem cells.
Golding MC, Zhang L, Mann MR.
Cell Stem Cell. 2010 May; 6(5):457-67.
PMID: 20452320 [PubMed - indexed for MEDLINE]
The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues.
Kuzmin A, Han Z, Golding MC, Mann MR, Latham KE, Varmuza S.
Gene Expr Patterns. 2008 Jan; 8(2):107-16.
PMID: 18024232 [PubMed - indexed for MEDLINE]
Cloning of GJA1 (connexin43) and its expression in canine ovarian follicles throughout the estrous cycle.
Willingham-Rocky LA, Golding MC, Wright JM, Kraemer DC, Westhusin ME, Burghardt RC.
Gene Expr Patterns. 2007 Jan; 7(1-2):66-71.
PMID: 16829210 [PubMed - indexed for MEDLINE]
Suppression of prion protein in livestock by RNA interference.
Golding MC, Long CR, Carmell MA, Hannon GJ, Westhusin ME.
Proc Natl Acad Sci U S A. 2006 Apr; 103(14):5285-90.
PMID: 16567624 [PubMed - indexed for MEDLINE]
Second-generation shRNA libraries covering the mouse and human genomes.
Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, Sheth N, Bradshaw J, Burchard J, Kulkarni A, Cavet G, Sachidanandam R, McCombie WR, Cleary MA, Elledge SJ, Hannon GJ.
Nat Genet. 2005 Nov; 37(11):1281-8.
PMID: 16200065 [PubMed - indexed for MEDLINE]
Evaluation of a real-time quantitative polymerase chain reaction assay for detection and quantitation of virulent Rhodococcus equi.
Harrington JR, Golding MC, Martens RJ, Halbert ND, Cohen ND.
Am J Vet Res. 2005 May; 66(5):755-61.
PMID: 15940818 [PubMed - indexed for MEDLINE]
Analysis of DNA (cytosine 5) methyltransferase mRNA sequence and expression in bovine preimplantation embryos, fetal and adult tissues.
Golding MC, Westhusin ME.
Gene Expr Patterns. 2003 Oct; 3(5):551-8.
PMID: 12971987 [PubMed - indexed for MEDLINE]
The mouse Na+-K+-ATPase gamma-subunit gene (Fxyd2) encodes three developmentally regulated transcripts.
Jones DH, Golding MC, Barr KJ, Fong GH, Kidder GM.
Physiol Genomics. 2001 Aug; 6(3):129-35.
PMID: 11526196 [PubMed - indexed for MEDLINE]