Diabetic retinopathy, novel bioactive peptides, circadian regulation of retinal physiology, signal tranduction in ion channel regulation
Ph.D. Neuroscience in Biomedical Sciences, Kent State U. affiliated w/ N.E. Ohio U Col. Med. 1996
M.S. Anatomical Sciences, National Yang-Ming Medical College, Taiwan 1991
B.S. Biology, National Chang-Kung University, Taiwan 1989
The Effects of Metformin on Obesity-Induced Dysfunctional Retinas.
Andy Jeesu Kim, Janet Ya-An Chang, Liheng Shi, Richard Cheng-An Chang, Michael Lee Ko, Gladys Yi-Ping Ko
Investigative ophthalmology & visual science.
Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice.
Liheng Shi, Andy Jeesu Kim, Richard Cheng-An Chang, Janet Ya-An Chang, Wei Ying, Michael L Ko, Beiyan Zhou, Gladys Yi-Ping Ko
A new role for AMP-activated protein kinase in the circadian regulation of L-type voltage-gated calcium channels in late-stage embryonic retinal photoreceptors.
Cathy C Y Huang, Liheng Shi, Chia-Hung Lin, Andy Jeesu Kim, Michael L Ko, Gladys Y-P Ko
Journal of neurochemistry.
Chicken embryos as a potential new model for early onset type I Diabetes.
Shi, L.*, Ko, M. L.*, Huang, C. C.-H., Park, S.-Y., Hong, M., Wu, C., Ko, G. Y.-P.
J. Diabetes Research.
Circadian phase-dependent effect of nitric oxide on L-type voltage-gated calcium channels in avian cone photoreceptors
Ko ML, Shi L, Huang CC, Grushin K, Park SY, Ko GY.
A new functional role for mechanistic/mammalian target of rapamycin complex 1 (TORC1) in the circadian regulation of L-type voltage-gated calcium channels in avian cone photoreceptors
Huang, C. C.-H., Ko, M. L., Ko, G. Y.-P.
Identification of Peptide lv, a novel putative neuropeptide that regulates the expression of L-type voltage-gated calcium channels in photoreceptors.
Shi L, Ko ML, Abbott LC, Ko GY
Calcineurin serves in the circadian output pathway to regulate the daily rhythm of L-type voltage-gated calcium channels in the retina.
Huang CC, Ko ML, Vernikovskaya DI, Ko GY
J Cell Biochem.
Cardiac-specific mutation of Clock alters the quantitative measurements of physical activities without changing behavioral circadian rhythms.
Ko ML, Shi L, Tsai JY, Young ME, Neuendorff N, Earnest DJ, Ko GY
J Biol Rhythms.
Rhythmic expression of microRNA-26a regulates the L-type voltage-gated calcium channel alpha1C subunit in chicken cone photoreceptors.
Shi L, Ko ML, Ko GY
J Biol Chem.
Inhibitory effect of somatostatin-14 on L-type voltage-gated calcium channels in cultured cone photoreceptors requires intracellular calcium.
Jian K, Barhoumi R, Ko ML, Ko GY
Circadian regulation of ion channels and their functions.
Ko GY, Shi L, Ko ML
Retinoschisin, a new binding partner for L-type voltage-gated calcium channels in the retina.
Shi L, Jian K, Ko ML, Trump D, Ko GY
J Biol Chem.
Circadian controls outweigh acute illumination effects on the activity of extracellular signal-regulated kinase (ERK) in the retina.
Ko ML, Shi L, Ko GY
Circadian regulation of retinoschisin in the chick retina.
Ko ML, Liu Y, Shi L, Trump D, Ko GY
Invest Ophthalmol Vis Sci.
The expression of L-type voltage-gated calcium channels in retinal photoreceptors is under circadian control.
Ko ML, Liu Y, Dryer SE, Ko GY