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Jonathan M Levine

Department Head & Professor


Phone: (979) 845-2351

Mailstop: 4474

Department: VSCS

Photo of Levine, Jonathan


  • N/A Residency, Neurology and Neurosurgery, Texas A&M/University of Missouri 2005
  • N/A Internship, Small Animal Medicine and Surgery, Colorado State University 2002
  • D.V.M. Veterinary Medicine, Cornell University 2001
  • B.S. Biology, Cornell University 1995


  • ACVIM (Neurology)
  • Texas Veterinary Medical License: 9993
  • Texas Veterinary Medical Specialty License: 0233-S

Clinical Areas of Interest

  • Neurology

Scholarly Interests

Spinal cord injury, in particular MR imaging and neuroprotectionNeuro-oncology


Putative Cerebral Microbleeds in Dogs Undergoing Magnetic Resonance Imaging of the Head: A Retrospective Study of Demographics, Clinical Associations, and Relationship to Case Outcome.
S C Kerwin, J M Levine, C M Budke, J F Griffin, C E Boudreau
Journal of veterinary internal medicine. 2017 31(4):1140-1148.
Early Blockade of Matrix Metalloproteinases in Spinal-Cord-Injured Dogs Results in a Long-Term Increase in Bladder Compliance.
Jonathan M Levine, Noah D Cohen, Thomas M Fandel, Gwendolyn J Levine, Joseph Mankin, John F Griffin, Sharon C Kerwin, C Elizabeth Boudreau, Alpa Trivedi, Linda J Noble-Haeusslein
Journal of neurotrauma. 2017
Evaluation of magnetic resonance imaging for the differentiation of inflammatory, neoplastic, and vascular intradural spinal cord diseases in the dog.
Amanda E Masciarelli, John F Griffin, Geoffrey T Fosgate, Silke Hecht, Joseph M Mankin, Shannon P Holmes, Simon R Platt, Marc Kent, Theresa E Pancotto, Annie V Chen, Jonathan M Levine
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. 2017 58(4):444-453.
Targeting Translational Successes through CANSORT-SCI: Using Pet Dogs To Identify Effective Treatments for Spinal Cord Injury.
Sarah A Moore, Nicolas Granger, Natasha J Olby, Ingo Spitzbarth, Nick D Jeffery, Andrea Tipold, Yvette S Nout-Lomas, Ronaldo C da Costa, Veronika M Stein, Linda J Noble-Haeusslein, Andrew R Blight, Robert G Grossman, D Michele Basso, Jonathan M Levine
Journal of neurotrauma. 2017 34(12):2007-2018.
The Association of Specific Constituents of the Fecal Microbiota with Immune-Mediated Brain Disease in Dogs.
Nick D Jeffery, Andrew K Barker, Cody J Alcott, Jon M Levine, Ilyssa Meren, Jane Wengert, Albert E Jergens, Jan S Suchodolski
PloS one. 2017 12(1):.
Multi-Center Retrospective Evaluation of Screw and Polymethylmethacrylate Constructs for Atlantoaxial Fixation in Dogs.
Megan W Stout Steele, Amy W Hodshon, Andrew L Hopkins, Gaemia M Tracy, Noah D Cohen, Sharon C Kerwin, C Elizabeth Boudreau, William B Thomas, Joseph M Mankin, Jonathan M Levine
Veterinary surgery : VS. 2016 45(7):909-915.
Arachidonic acid pathway alterations in cerebrospinal fluid of dogs with naturally occurring spinal cord injury
Russell RL, Levine JM, Jeffery ND, Mondragon A, Lee B, Boudreau CE, Welsh CJ, Levine GJ
BMC Neurosci. 2016 17:31.
Application of a frameless computed tomography-guided stereotactic biopsy system for the collection of nasal biopsies in dogs: 5 cases (2012-2014)
Kuhlman GM, Taylor AR, Griffin JF, Thieman KT, Cook AK, Levine JM
J Am Vet Med Assoc. 2016 248:929-934.
Magnetic resonance imaging and clinical features of dogs with central nervous system aspergillosis
aylor AR, Young BD, Levine GJ, Eden K, Corapi W, Rossmeisl JH, Levine JM
J Vet Intern Med. 2015 29:1556-1563.
Prospective cohort study to analyze physical and temporal prognostic factors associated with recovery from paraplegia in dogs that have lost deep pain perception
Jeffery ND, Baker A, Alcott, Hu HZ, Kraus K, Scanlin E, Granger N, Levine JM
J Am Vet Med Assoc. 2015
High-resolution MRI of spinal cords by compressive sensing parallel imaging
Li P, Yu X, Griffin J, Levine JM, Ji J
IEEE Eng Med Biol Soc. 2015
Acute Phase Proteins in Cerebrospinal Fluid from Dogs with Naturally-Occurring Spinal Cord Injury.
Anderson KM, Welsh CJ, Young C, Levine GJ, Kerwin SC, Boudreau CE, Reyes I, Mondragon A, Griffin JF 4th, Cohen ND, Levine JM
J Neurotrauma. 2015
Cerebral oligodendroglioma mimicking intraventricular neoplasia in 3 dogs
Rissi DR, Levine JM, Eden KB, Watson VE, Griffin JF, Edwards JF, Porter BF
J Vet Diagn Invest. 2015
Quantitative magnetic resonance imaging in a naturally occurring canine model of spinal cord injury.
Griffin JF, Davis MC, Ji JX, Cohen ND, Young BD, Levine JM
Spinal Cord. 2015 53(4):278-84.
Lynphocytic ganglioneuritis secondary to intervertebral disc extrusion in a dog
Mouradian-Darby AE, Young BD, Griffin JF, Mansell J, Levine JM
J Small Anim Pract. 2014
Effect of miR-142-3p on the M2 macrophage and therapeutic efficacy against murine glioblastoma.
Xu S, Wei J, Wang F, Kong LY, Ling XY, Nduom E, Gabrusiewicz K, Doucette T, Yang Y, Yaghi NK, Fajt V, Levine JM, Qiao W, Li XG, Lang FF, Rao G, Fuller GN, Calin GA, Heimberger AB
J Natl Cancer Inst. 2014 106(8):.
Relationships between cerebrospinal fluid characteristics, injury severity, and functional outcome in dogs with and without intervertebral disk herniation
Levine GJ, Cook JR, Kerwin SC, Mankin J, Griffin JF, Fosgate GT, Levine JM
Vet Clini Pathol. 2014
A comparison of clinical, magnetic resonance imaging, and pathological findings in dogs with gliomatosis cerebri, focusing on cases with minimal magnetic resonance imaging changes
Bentley RT, Burcham GN, Heng HG, Levine JM, Longshore R, Carrera-Justiz S, Cameron S, Koft K, Miller MA
Vet Comp Oncol. 2014
Lymphocytic ganglioneuritis secondary to intervertebral disc extrusion in a dog
Mouradian-Darby AE, Young BD, Griffin JF, Mansell J, Levine JM
J Small Anim Pract. 2014
Cerebrospinal fluid inflammatory cytokines and chemokines in naturally-occurring canine spinal cord injury
Taylor AR, Welsh J, Young C, Spoor E, Kerwin SC, Griffin JF, Levine GJ, Cohen ND, Levine JM
J Neurotrauma. 2014
Inflammatory cytokines in cerberospinal fluid of dogs with acute spinal cord injury
Taylor AR, Welsh J, Young C, Cohen ND, Levine GJ, Levine JM
Comparison between noncontrast computed tomography and magnetic resonance imaging for detection and characterization of thoracolumbar myelopathy caused by intervertebral disk herniation in dogs
Cooper JJ, Young BD, Griffin JF, Fosgate GT, Levine JM
Vet Radiol Ultrasound. 2014 55(55):182-189.
Matrix metalloproteinase inhibitor, GM6001 improves bladder and locomotor function after moderate-severe contusion spinal cord injury in mice
Trivendi A, Fandel TM, Martinez AF, Zhang H, Levine JM, Noble-Haeusslein LJ
Intervertebral disc degeneration in dogs: consequences, diagnosis, treatment, and future directions
Jeffery ND, Levine JM, Olby NJ, Stein V
J Vet Intern Med. 2013 27(27):1318-1333.
Acute treatment with the matrix maetalloproteinase inhibitor GM 6001 improves long-term locomotor and bladder function in a murine model of spinal cord injury
Fandel TM, Trivendi A, Gimlin K, Zhang H, Levine JM, Martinez AF, Noble-Haeusslein LJ
Evaluator agreeement and outcome associations in dogs with spinal cord injury caused by intervertebral disk herniation
Griffin JF, Davis MC, Cohen ND, Young BY, Levine JM
Prospectively recorded versus medical record-derived spinal cord injury scores in a cohort of dogs with intervertebral disk herniation
Van Wie EY, Fosgate GT, Mankin JM, Jeffery ND, Kerwin SC, Levine GJ, Greatting HH, Chen AV, Levine JM
J Vet Intern Med. 2013 27(27):1273-1277.
Imaging diagnosis-synovial myxoma of lumbar vertebrae articular process joint.
Blair WH, Levine JM, Kerwin SC, Spaulding KA, Young BD, Pool RR
Vet Radiol Ultrasound. 2011 52(3):309-12.
Naturally occurring disk herniation in dogs: an opportunity for pre-clinical spinal cord injury research.
Levine JM, Levine GJ, Porter BF, Topp K, Noble-Haeusslein LJ
J Neurotrauma. 2011 28(4):675-88.
Canine astrocytic tumors: a comparative review.
Stoica G, Levine J, Wolff J, Murphy K
Vet Pathol. 2011 48(1):266-75.
Intracranial magnetic resonance imaging artifacts and pseudolesions in dogs and cats.
Cooper JJ, Young BD, Hoffman A, Bratton G, Hicks DG, Tidwell A, Levine JM
Vet Radiol Ultrasound. 2010 51(6):587-95.
Multicenter case-control study of signalment, diagnostic features, and outcome associated with cervical vertebral malformation-malarticulation in horses.
Levine JM, Scrivani PV, Divers TJ, Furr M, Mayhew IJ, Reed S, Levine GJ, Foreman JH, Boudreau C, Credille BC, Tennent-Brown B, Cohen ND
J Am Vet Med Assoc. 2010 237(7):812-22.
Cerebrospinal fluid myelin basic protein as a prognostic biomarker in dogs with thoracolumbar intervertebral disk herniation.
Levine GJ, Levine JM, Witsberger TH, Kerwin SC, Russell KE, Suchodolski J, Steiner J, Fosgate GT
J Vet Intern Med. 2010 24(4):890-6.
Evaluation of brain tissue or cerebrospinal fluid with broadly reactive polymerase chain reaction for Ehrlichia, Anaplasma, spotted fever group Rickettsia, Bartonella, and Borrelia species in canine neurological diseases (109 cases).
Barber RM, Li Q, Diniz PP, Porter BF, Breitschwerdt EB, Claiborne MK, Birkenheuer AJ, Levine JM, Levine GJ, Chandler K, Kenny P, Nghiem P, Wei S, Greene CE, Kent M, Platt SR, Greer K, Schatzberg SJ
J Vet Intern Med.. 2010 24(2):372-8.
Imaging diagnosis--magnetic resonance imaging pseudolesion associated with the petrous temporal bone.
Cooper JJ, Levine JM, Young BD, Hicks DG, Hoffman A, Bratton G
Vet Radiol Ultrasound. 2010 51(1):39-41.
Arrhythmias and elevated troponin I in a dog with steroid-responsive meningitis-arteritis.
Snyder K, Saunders AB, Levine JM, Clubb FJ
J Am Anim Hosp Assoc. 2010 46(1):61-5.
Pregabalin as an adjunct to phenobarbital, potassium bromide, or a combination of phenobarbital and potassium bromide for treatment of dogs with suspected idiopathic epilepsy.
Dewey CW, Cerda-Gonzalez S, Levine JM, Badgley BL, Ducoté JM, Silver GM, Cooper JJ, Packer RA, Lavely JA
J Am Vet Med Assoc.. 2009 235(12):1442-9.
Broadly reactive pan-paramyxovirus reverse transcription polymerase chain reaction and sequence analysis for the detection of Canine distemper virus in a case of canine meningoencephalitis of unknown etiology.
Schatzberg SJ, Li Q, Porter BF, Barber RM, Claiborne MK, Levine JM, Levine GJ, Israel SK, Young BD, Kiupel M, Greene C, Ruone S, Anderson L, Tong S
J Vet Diagn Invest.. 2009 21(6):844-9.
Magnetic resonance imaging in dogs with neurologic impairment due to acute thoracic and lumbar intervertebral disk herniation.
Levine JM, Fosgate GT, Chen AV, Rushing R, Nghiem PP, Platt SR, Bagley RS, Kent M, Hicks DG, Young BD, Schatzberg SJ
J Vet Intern Med. 2009 23(6):1220-6.
The relative sensitivity of computed tomography and myelography for identification of thoracolumbar intervertebral disk herniations in dogs.
Israel SK, Levine JM, Kerwin SC, Levine GJ, Fosgate GT
Vet Radiol Ultrasound. 2009 50(3):247-52.
Description and repeatability of a newly developed spinal cord injury scale for dogs.
Levine GJ, Levine JM, Budke CM, Kerwin SC, Au J, Vinayak A, Hettlich BF, Slater MR
Prev Vet Med. 2009 89(1-2):121-7.
Identification of cancer stem cells in dog glioblastoma.
Stoica G, Lungu G, Martini-Stoica H, Waghela S, Levine J, Smith R 3rd
Vet Pathol. 2009 46(3):391-406.
Cervical vertebral malformation-malarticulation syndrome in the Bernese mountain dog: clinical and magnetic resonance imaging features.
Eagleson JS, Diaz J, Platt SR, Kent M, Levine JM, Sharp NJ, Schatzberg SJ
J Small Anim Pract.. 2009 50(4):186-93.
Imaging diagnosis--chronic canine distemper meningoencephalitis.
Griffin JF 4th, Young BD, Levine JM
Vet Radiol Ultrasound. 2009 50(2):182-4.
Immunohistochemical features of a feline spinal cord gemistocytic astrocytoma.
Aloisio F, Levine JM, Edwards JF
J Vet Diagn Invest. 2008 20(6):836-8.
Associations of sex, breed, and age with cervical vertebral compressive myelopathy in horses: 811 cases (1974-2007).
Levine JM, Ngheim PP, Levine GJ, Cohen ND
J Am Vet Med Assoc. 2008 233(9):1453-8.
Meningomyelitis in dogs: a retrospective review of 28 cases (1999 to 2007).
Griffin JF, Levine JM, Levine GJ, Fosgate GT
J Small Anim Pract. 2008 49(10):509-17.
Owner-perceived, weighted quality-of-life assessments in dogs with spinal cord injuries.
Levine JM, Budke CM, Levine GJ, Kerwin SC, Hettlich BF, Slater MR
J Am Vet Med Assoc. 2008 233(6):931-5.
Evaluation of a questionnaire for obtaining owner-perceived, weighted quality-of-life assessments for dogs with spinal cord injuries.
Budke CM, Levine JM, Kerwin SC, Levine GJ, Hettlich BF, Slater MR
J Am Vet Med Assoc. 2008 233(6):925-30.
Cervical spinal locking plate in combination with cortical ring allograft for a one level fusion in dogs with cervical spondylotic myelopathy.
Bergman RL, Levine JM, Coates JR, Bahr A, Hettlich BF, Kerwin SC
Vet Surg.. 2008 37(6):530-6.
Epidemiology of necrotizing meningoencephalitis in Pug dogs.
Levine JM, Fosgate GT, Porter B, Schatzberg SJ, Greer K
J Vet Intern Med. 2008 22(4):961-8.
Randomized, blinded, placebo-controlled clinical trial of N-acetylcysteine in dogs with spinal cord trauma from acute intervertebral disc disease.
Baltzer WI, McMichael MA, Hosgood GL, Kerwin SC, Levine JM, Steiner JM, Ruaux CG
Spine (Phila Pa 1976). 2008 33(13):1397-402.
Adverse effects and outcome associated with dexamethasone administration in dogs with acute thoracolumbar intervertebral disk herniation: 161 cases (2000-2006).
Levine JM, Levine GJ, Boozer L, Schatzberg SJ, Platt SR, Kent M, Kerwin SC, Fosgate GT
J Am Vet Med Assoc. 2008 232(3):411-7.
Confirmed and presumptive cervical vertebral compressive myelopathy in older horses: a retrospective study (1992-2004).
Levine JM, Adam E, MacKay RJ, Walker MA, Frederick JD, Cohen ND
J Vet Intern Med. 2007 21(4):812-9.
Evaluation of the success of medical management for presumptive cervical intervertebral disk herniation in dogs.
Levine JM, Levine GJ, Johnson SI, Kerwin SC, Hettlich BF, Fosgate GT
Vet Surg. 2007 36(5):492-9.
Evaluation of the success of medical management for presumptive thoracolumbar intervertebral disk herniation in dogs.
Levine JM, Levine GJ, Johnson SI, Kerwin SC, Hettlich BF, Fosgate GT
Vet Surg. 2007 36(5):482-91.
Dystrophin-deficient muscular dystrophy in a Weimaraner.
Baltzer WI, Calise DV, Levine JM, Shelton GD, Edwards JF, Steiner JM
J Am Anim Hosp Assoc.. 2007 43(4):227-32.
Imaging diagnosis--bacterial diskospondylitis in a goat.
Levine GJ, Bissett WT, Cole RC, Janke JJ, Nunes J, Porter B, Levine JM
Vet Radiol Ultrasound. 2006 47(6):585-8.
Association between various physical factors and acute thoracolumbar intervertebral disk extrusion or protrusion in Dachshunds.
Levine JM, Levine GJ, Kerwin SC, Hettlich BF, Fosgate GT
J Am Vet Med Assoc. 2006 229(3):370-5.
Matrix metalloproteinase-9 activity in the cerebrospinal fluid and serum of dogs with acute spinal cord trauma from intervertebral disk disease.
Levine JM, Ruaux CG, Bergman RL, Coates JR, Steiner JM, Williams DA
Am J Vet Res. 2006 67(2):283-7.
Evaluation of the association between spondylosis deformans and clinical signs of intervertebral disk disease in dogs: 172 cases (1999-2000).
Levine GJ, Levine JM, Walker MA, Pool RR, Fosgate GT
J Am Vet Med Assoc. 2006 228(1):96-100.
Myasthenia gravis and hypothyroidism in a dog with meningomyelitis.
Levine JM, Bergman RL, Coates JR, Shelton GD
J Am Anim Hosp Assoc. 2005 41(4):247-51.
Use of an ankle-foot orthosis in a dog with traumatic sciatic neuropathy.
Levine JM, Fitch RB
J Small Anim Pract.. 2003 44(5):236-8.
Cerebrospinal fluid from a dog with neurologic collapse.
Thompson CA, Russell KE, Levine JM, Weeks BR
Vet Clin Pathol. 2003 32(3):143-6.
The influence of age on patellar reflex response in the dog.
Levine JM, Hillman RB, Erb HN, deLahunta A
J Vet Intern Med.. 2002 16(3):244-6.
Creation of an NCI comparative brain tumor consortium: informing the translation of new knowledge from canine to human brain tumor patients
LeBlanc AK, Mazcko C, Brown DB, Koehler JW, Miller AD, Miller CR, Bentley RT, Packer RA, Breen M, Boudreau CE, Levine JM, Simpson MR, Halsey C, Kisseberth W, Rossmeisl JH, Dickinson PJ, Fan T, Corps K, Aldape K, Puduvalli V, Pluhar GE, Gilbert MR
Neuro Oncol. ePub PMID 27179361.

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