Graduate Courses

Veterinary Microbiology (VTMI)

601. Fundamentals of Pathobiology. (5-0). Credit 5. Encompasses the concepts of pathobiology including bacterial, viral and parasitic diseases, the host response to infectious agents, pathology, and metabolic and genetic diseases; includes animal and human diseases and provides enough background to facilitate students in advanced graduate courses. Prerequisite(s): Graduate classification.

614. Fermentation and Gastrointestinal Microbiology. (3-0). Credit 3. Fermentation and gastrointestinal ecosystems in terms of microorganisms present, their activities and requirements and their interactions in a dynamic system. Prerequisite: Beginning microbiology and/or biochemistry or approval of instructor. Cross-listed with POSC 614 and NUTR 614.

615.  Immunogenetics and Comparative Immunology. (3-0).  Credit 3. Genetic mechanisms used to diversify immune receptors, immunoglobulins, T cell receptors, major histocompatibility complex, natural killer cell receptors, toll-like receptors and many others; selected comparative and veterinary examples of different immune recognition systems; evolution of the immune system; theoretical immune surveillance and vaccine development. Prerequisites: Graduate classification, GENE 320 and VTPB 409 or equivalent, or approval of instructor

619. Molecular Methods for Microbial. (2-2). Credit 3. Underlying principles of molecular methods for microbial detection and characterization in natural and man-made ecosystems; emphasis on method application and data interpretation; emphasis on microbial pathogens and indicator organisms in foods and environment; laboratory covers select protocols. Prerequisite: POSC 429/FSTC 326/AGRO 405/approval of instructor. Cross-listed with AGRO 619/FSTC 619/POSC 619.

629.  Laboratory Quality Systems. (3-0) Credit 3. Quality systems and method development used within a laboratory, ensuring the integrity of procedures used in lab processes, chain of custody, information management, and international laboratory standards; regulatory requirements for laboratory operation; bio-security precautions; laboratory management.  Cross-listed with SCSC 629.

643. Pathogenic Bacteriology I. (3-4). Credit 4. Pathogenic bacteria, their cultural and biological characteristics and pathogenicity. Prerequisite: Minimum of eight hours of undergraduate microbiology.

645. Host Agent Interactions In Veterinary Medicine. (3-0). Credit 3. Basic concepts of infection versus disease. Interdisciplinary approaches to problems in microbiology; inducible host responses, agent escape mechanisms and movement of potential pathogens in the ecosystem. Prerequisite: VTMI 405 or equivalent.

647. Virology. (3-3). Credit 4. Virus infections in animals; types of infections, mode of transmission, intracellular pathology, epidemiology, isolation and identification of inciting agents. Tissue cultivation, animal inoculations and diagnostic tests. Prerequisite: VTMI 438 or equivalent.

648. Medical Mycology. (3-3). Credit 4. Actinomycetes, yeasts and molds that are pathogenic to humans and animals; morphology, cultural characteristics, pathogenicity and identification. Practice consists of exercises in cultural methods, morphological characteristics, biochemical reactions and diagnosis. Prerequisite: Minimum of eight hours of undergraduate microbiology.

649. Immunology. (3-0). Credit 3. Cellular basis of the immune response; relationships between inflammation and acquired immunity. MHC and cell activation; the role of cytokines in inflammation and acquired immunity. MHC and cell activation; the role of cytokines in immunoregulation and hypersensitivity, vaccines, and the mechanism of immunity to viruses, bacteria and parasites. Prerequisite: VTPB 409 or equivalent. Cross-listed with POSC 649.

650. Experimental Immunology. (3-3). Credit 4. Familiarization, development and integration of techniques into experimental design of immunologic investigation. Virus and protein purification, immunofluorescence, agar diffusion, immunoelectrophoresis, germ free animal techniques and specialized serologic tests. Cross-listed with POSC 660.

654. Tissue Culture Techniques. (1-9). Credit 4. Tissue culture techniques particularly in application to virus isolation; principles of cell, organ and explant culture in vitro. Prerequisites: VTMI 647 or equivalent; graduate classification.

662. Advanced Immunologic Concepts. (5-0). Credit 1-5. Modular course with detailed discussions, workshops and assigned reading/problem solving on advanced topics; structural organization of molecules; genetic regulation; cytokine cascades; pathophysiology of autoimmunity. May be repeated for credit.

663. Molecular Biology of Animal Viruses. (3-0) Credit 3. In-depth studies of the biochemistry and replication strategies of animal viruses and molecular mechanisms of pathogenesis for selected viral systems. Prerequisites: Graduate classification in virology, molecular biology, biochemistry or approval of instructor. Cross-listes with MIMM 663.

664. Strategies for Manipulating the Mouse Genome. (3-0). Credit 3. This course will provide students with an in-depth working knowledge of the strategies used to modify the mouse genome, including transgenes, homologous recombination-based gene targeting, gene trapping, siRNA interference, size-specific recombinases, and inducible systems.

681. Seminar. (10). Credit 1. Review and discussion of current scientific work and research in field of microbiology and related subjects. Prerequisite: Graduate major or minor in microbiology or related fields.

685. Directed Studies. Credit 1-4 each semester. Problems course in microbiology. Prerequisites: Approval of department head.

689. Special Topics. Credit 1-4. Selected topics in an identified area of veterinary microbiology. May be repeated for credit. Prerequisite: Approval of instructor.

691. Research. Credit 1 or more with maximum of 23. Research for thesis or dissertation.

665.  Viral Vectors and Gene Therapy. (3-0). Credit 3. This course will describe various viral vector systems, their development and their use as research tools in biotechnology and gene therapy.  The course will consist of a mixture of short lectures and discussion of papers from the literature.  Prerequisites:  VTMI 663, VTMI 647, PLPA 616, or PLPA 620 or approval of instructor.  Cross-listed with MMPA 665 and PLPA 665.

Veterinary Parasitology (VPAR)

601. Parasitology. (3-3). Credit 4. Important helminth parasites of domestic and laboratory animals; their identification, distribution and life history. Prerequisite: VTPB 487 or equivalent.

604. Parasitic Protozoa. (3-3). Credit 4. Taxonomy, morphology, life cycle, physiology, distribution, genetics, host relations, methods and diagnosis concerned with protozoan parasites affecting vertebrates including humans. Prerequisite: VPAR 484 or BIOL 108 or 438 or ENTO 208 or equivalent.

605. Molecular and Immunological Parasitology. (3-0). Credit 3. Immunologic processes involved in natural and acquired resistance to parasitic infections. Prerequisites: VPAR 487 and VTMI 640 or equivalents.

685. Directed Studies. Credit 1-4 each semester. Special problems concerned with parasites of domestic animals or poultry. Prerequisites: VPAR 601 or equivalent; approval of instructor.

689. Special Topics in... Credit 1-4. Selected topics in an identified area of biomedical parasitology. May be repeated for credit.

691. Research. Credit 1 or more each semester. Research for thesis.

Veterinary Pathology (VPAT)

601. Comparative Pathology. (3-3). Credit 4. Pathologic processes occurring in diseased cells, tissues and organs of animals and humans; their pathogenesis and morphologic manifestations. Prerequisites: Courses in gross and microscopic mammalian anatomy and physiology and approval of instructor.

620. Humane, Public Health and Regulatory Aspects of Animal Use. (1-0). Credit 1. Emphasizes thoughtful and humane use of animals in teaching, research and service; human and animal health benefits of biomedical research; governmental policies regulations, public health implications, management practices, and public relations pertaining to animal use in research and teaching.

640. Mechanisms of Disease. (3-0). Credit 3. Concepts of pathogenesis of disease in animals. Prerequisite: D.V.M. degree or approval of department head.

641. Systemic Pathology I. (2-4). Credit 4. Disease manifestations in special organs and tissues and interrelations of pathologic processes in individual and functionally related organs. Prerequisite: D.V.M. degree or equivalent.

642. Mechanisms of Metabolic Disease. (3-0). Credit 3. Characteristics and mechanisms of diseases caused either by deficiency, imbalance, excess of specific nutrients or chemicals, or by regulatory disturbances of metabolism. Prerequisite: D.V.M. degree or approval of department head.

643. Applied Pathology. Credit 1 or more each semester. Application of information and concepts of anatomic and clinical pathology to the diagnosis of animal disease; gross pathological changes observed in necropsy are correlated with and corrected by histopathologic observations; confirmatory methods of clinical pathology and laboratory medicine used where indicated. May be taken more than once but not to exceed 6 hours of credit toward a graduate degree. Prerequisite: D.V.M. degree or equivalent.

645. Neoplastic Diseases. Credit 1-8. Theoretical, histopathological and clinical aspects of neoplasia. Diagnosis of neoplastic and related conditions in all species. May be taken more than once but not to exceed 8 hours of credit toward a graduate degree Prerequisite: D.V.M. degree or equivalent.

650.Neuropathology of Animals. Credit 1-4. Pathology and pathogenesis of diseases of the central and peripheral nervous systems. Interpretation of gross and microscopic lesions of the nervous system associated with disease processes. May be taken more than once but not to exceed 4 hours of credit toward a graduate degree. Prerequisite: D.V.M. degree or equivalent.

651. Systemic Pathology II. (1-3) Credit 2. Continuation of VPAT 641. Disease manifestations in special organs and tissues and interrelations of pathologic processes in individual and functionally related organs. Prerequisite: VPAT 641.

653. Diseases of Laboratory Animals. (2-2). Credit 3. Pathology and pathogenesis of spontaneous infectious, parasitic, metabolic and neoplastic diseases of laboratory animals. Prerequisite: VMID 922 or equivalent.

681. Seminar. (10). Credit 1. For graduate and special students in veterinary pathology. Presentation and discussion of special topics and research data concerning pathology and pathogenesis of diseases. Prerequisite: Approval of department head.

685. Directed Studies. Credit 1-4 each semester. Advanced special problems concerned with pathogenesis and pathology of disease. Prerequisite: Approval of department head.

689. Special Topics. Credit 1-4. Selected topics in an identified area of veterinary pathology. May be repeated for credit.

690. Theory of Research. (3-0). Credit 3. Theory and design of research related to current biomedical problems especially those involving study of animal disease. Philosophical perspectives underlying historical advances in research pertaining to the study, prevention and treatment of disease. Prerequisite: Graduate classification.

691. Research. Credit 1 or more each semester. Research reported by writing of thesis or dissertation as partial requirement for M.S. or Ph.D. degree.

Genetics (GENE) and Molecular and Cell Biology

603. Genetics. (4-0). Credit 4. Development of fundamental concepts related to the structure, function, organization, transmission and distribution of genetic material. Prerequisite: GENE 301 or equivalent.

610. Mammalian Immunogenetics. (3-0). Credit 3. Basic immunogenetics concepts derived from mouse, rabbit and human, and applied to domestic or other laboratory animal species; theory and techniques in immunohematology, histocompatibility genetics, genetics of immunoglobulins, genetics of immune responsiveness. Prerequisites: GENE 301, BIOL 458.

612. Population Genetics. Credit 3.Biological approach to genetic characteristics of populations dealing with genetic equilibrium, allelic variation, determination of genetic variation in populations, effects of mating systems, selection, mutation and ploidy on population parameters. Prerequisites: GENE 603 STAT 651.

613. Quantitative Genetics I. Credit 3. Quantitative genetics concepts particularly dealing with partitioning of phenotypic variance into genetic and environmental components, selection response, effects of systems of mating, genetic covariance and threshold effects. Prerequisites: GENE 612; STAT 652.

614. Maximum Likelihood Estimation of Genetics. (3-0). Credit 3. Theoretical and analytical approaches to the application of maximum likelihood for the estimation of parameters under linear and non-linear models; single and polygene genetic models including Hardy-Weinberg equilibrium, linkage analysis and quantitative trait loci detection. Prerequisites: STAT 651, STAT 652 or 601, GENE 603. Cross-listed with ANSC 614.

620. Cytogenetics. Credit 3. Examination and analysis of variation in chromosome structure, behavior and number; developmental and evolutionary effects of this variation. Prerequisite: GENE 603.

626. Analysis of Gene Expression. (0-3). Credit 1. Proficiency in handling DNA and RNA gained during exercises used routinely in analyses of gene expression; RNA preparation and analysis of Northern blots; in vitro transcription and polyacrylamide gel analysis of nucleic acids, sub-cloning and mRNA quantitation using polymerase chain reaction. Prerequisites: BICH/GENE 450 or approval of instructor, radiation safety training. Cross-listed with ANSC 626.

631. Biochemical Genetics. (3-0). Credit 3. Genetic control of cellular metabolism. Mechanism of gene action; gene-enzyme relationships; regulation of gene expression; structure and organization of genomes; biochemical manipulation and characterization of genetic molecules. Prerequisites: BICH 604 or GENE 431. Cross-listed with BICH 631.

654. Analysis of Complex Genomes. (3-0). Credit 3. History and current status of genetic and molecular analysis of higher eukaryotic genomes; coverage of techniques for dissection of genomes into manageable parts; investigations in genetics, breeding and evolution; emphasis on quantitative inheritance, genetic mapping, physical mapping, map-based cloning, with examples drawn from a wide range of organisms. Prerequisite: GENE 603. Cross-listed with AGRO 654 and PPHY 654.

662. Eukaryotic Transcription. (1-0). Credit 1. Intensive short course in molecular mechanisms of eukaryotic transcription and it's regulation. Prerequisite: BICH/GENE 661 or approval of instructor. Cross-listed with BICH 662.

681. Seminar. (1-0). Credit 1.Reports and discussions of topics of current importance in genetics; reports to be prepared and presented by graduate students enrolled in course.

685. Directed Studies. Credit 1-4 each semester. Individual problems or research not pertaining to thesis or dissertation. Prerequisite: Approval of instructor.

689. Special Topics in... Credit 1-4. Selected topics in an identified area of genetics. May be repeated for credit. Prerequisite: Approval of instructor.

691. Research. Credit 1 or more each semester. Prerequisite: GENE 603.

697. Teaching Genetics Labs. (1-0). Credit 1. Theory and practical aspects of teaching genetics labs, with emphasis on content, grading, instructional methods, and practical aspects of genetics labs. May be repeated for credit. Prerequisites: Graduate classification in genetics; appointment as a TA for genetics labs.