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Gonzalo Rivera

Associate Professor

Curriculum Vitae

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Phone: (979) 458-0128

Mailstop: 4467

Department: VTPB

Photo of Rivera, Gonzalo

Education

  • Ph.D. Physiology, Cornell University 2002
  • M.S. Physiology, National University of Mar del Plata, Argentina 1991
  • D.V.M. Veterinary Medicine, National University of Rio Cuarto, Argentina 1988

Credentials

  • DVM
  • MS Animal Science
  • PhD Physiology

Scholarly Interests

My laboratory is interested in the role played by cytoskeletal remodeling in development and disease, particularly, angiogenesis and tumor progression and invasion. The long-term goal of our research is to understand how extracellular signals that alter tyrosine phosphorylation and the metabolism of inositol phospholipids modulate actin dynamics and cell motility. Areas of interest include the biogenesis of actin-based structures of invasion, intracellular trafficking, and three-dimensional tissue morphogenesis in vitro. Our research employs a combination of molecular genetics, cell biology, proteomics, and high-resolution optical imaging.

Publications

Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics.
Chaki SP, Barhoumi R, Berginski ME, Sreenivasappa H, Trache A, Gomez SM, Rivera GM
J Cell Sci. 126(Pt 7):1637-49.
Integration of signaling and cytoskeletal remodeling by Nck in directional cell migration.
Chaki SP, Rivera GM
Bioarchitecture. 3(3):57-63.
Selective regulation of cytoskeletal tension and cell-matrix adhesion by RhoA and Src.
Harini Sreenivasappa H., Sankar P. Chaki, S. P., Lim, S. M, Trzeciakowski, J. P., Davidson M., Rivera, G. M. and Trache, A.
Actin remodeling by Nck regulates endothelial lumen formation.
Chaki SP, Barhoumi R, Rivera GM
Mol Biol Cell.
Protein tyrosine phosphatase-PEST and β8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cells.
4. Lee HS, Cheerathodi M, Chaki SP, Reyes SB, Zheng Y, Lu Z, Paidassi H, DerMardirossian C, Lacy-Hulbert A, Rivera GM, McCarty JH
Mol Cell Biol.


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