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Sankar P Chaki

Research Assistant Professor

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Phone: (979) 862-8490

Mailstop: 4467

Department: VTPB

Photo of Chaki, Sankar

Selective Publications

1. Arenas-Gamboa AM, Rossetti CA, Chaki SP, Garcia-Gonzalez DG, Adam LG, and Ficht TA (2016) Human Brucellosis and Adverse Pregnancy Outcomes. Curr Trop Med Rep (DOI 10.1007/s40475-016- 0092-0).

2. Chaki SP, Barhoumi R and Rivera GM (2015) Cytoskeletal remodeling by Nck regulate endothelial lumen formation and promote angiogenesis. Mol. Biol. Cell. 26: 3047-3060. Cover page image.

3. Lee HS, Cheerathodi M, Chaki SP, Reyes SB, Zheng Y, Lu Z, Paidassi H, DerMardirossian C, Hulbert AL, Rivera GM and McCarty J (2015) PTP-PEST and ß8 Integrin Regulate Spatiotemporal Patterns of RhoGDI1 Activation in Migrating Cells. Mol. Cell. Biol. 35:1401-13.

4. Chaki SP and Rivera GM (2013) Integration of Signaling and Cytoskeletal Remodeling by Nck in Directional Cell Migration. BioArchitecture. 3: 57-63.

5. Chaki SP, Barhoumi R, Sreenivasappa H, Trache A, Gomez SM and Rivera GM (2013) Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics. J. Cell. Sci. 126:1637-1649.

6. Misro MM and Chaki SP (2008) Development of a rapid, sensitive and reproducible laboratory test kit for the assessment of plasma membrane integrity of human sperms. Fertility & Sterility 89 (1): 223-7.

7. Chaki SP, Misro MM, Gautam DK, Ghosh D and Chainy GB (2006) Estradiol treatment induces testicular oxidative stress and germ cell apoptosis in rats. Apoptosis 11:1427-37.

8. Chaki SP, Misro MM, Ghosh D, Dinesh K Gautam & Srinivas M (2005) Apoptosis and cell removal in the cryptorchid rat testis. Apoptosis 10 (2): 395-405.

9. Chaki SP, Ghosh D and Misro MM (2003) Simultaneous increase in germ cell apoptosis and oxidative stress under acute unilateral testicular ischemia in rats. Int. J. Androl 26: 319-328.

10. Chaki SP, Das HC and Misro MM (2003) A short-term evaluation of semen and accessory sex gland function in phase III trial subjects receiving intravasal contraceptive RISUG. Contraception 67:73-78.

11. Chaki SP and Misro MM (2002) Assessment of human sperm function after hydrogen peroxide exposure: development of a vaginal contraceptive. Contraception 66: 187-192.

Education

  • Ph.D Physiology, National Institute of Health & Family Welfare, Ind 2005

Credentials

  • Biosafety level 3 training completed

Scholarly Interests

Cell and molecular biology, Quantitative imaging, actin cytoskeletal dynamics in health and diseases, male fertility management, host-pathogen interaction, improve diagnostics and vaccine development for microbial infections.

Publications

Human Brucellosis and Adverse Pregnancy Outcomes
Arenas-Gamboa AM, Rossetti CA, Chaki SP, Garcia-Gonzalez DG, Adam LG, and Ficht TA
Curr Trop Med Rep . 2016
Actin Remodeling by Nck Regulates Endothelial Lumen Formation.
Chaki SP, Barhoumi R, Rivera GM
Mol Biol Cell. 2015
Protein tyrosine phosphatase-PEST and β8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cells.
Lee HS, Cheerathodi M, Chaki SP, Reyes SB, Zheng Y, Lu Z, Paidassi H, DerMardirossian C, Lacy-Hulbert A, Rivera GM, McCarty JH
Mol Cell Biol. 2015 35(8):1401-13.
Selective regulation of cytoskeletal tension and cell-matrix adhesion by RhoA and Src.
Sreenivasappa H, Chaki SP, Lim SM, Trzeciakowski JP, Davidson MW, Rivera GM, Trache A
Integr. Biol. 2014
Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics.
Chaki SP, Barhoumi R, Berginski ME, Sreenivasappa H, Trache A, Gomez SM, Rivera GM
J Cell Sci. 2013 126(Pt 7):1637-49.


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