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Brad Weeks

Professor

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Phone: (979) 845-0789

Mailstop: 4467

Department: VTPB

Photo of Weeks, Brad

Education

  • Ph.D. Veterinary Pathology, Kansas State University 1988
  • Residency in Veterinary Pathology Anatomic Pathology, Kansas State University 1988
  • D.V.M. Veterinary Medicine, Oklahoma State University 1983
  • B.S. Zoology, Oklahoma State University 1979

Credentials

  • Licensed to Practice Veterinary Medicine, KS
  • Professor, Dept. of Veterinary Pathobiology,
  • Diplomate, American College of Veterinary Pathologists, (ACVP)
  • Licensed to practice Veterinary Medicine, TX Individual License # 10969:

Scholarly Interests

Diagnostic anatomic pathology; collaborative research of inflammatory and neoplastic gastrointestinal disease, and cardiovascular disease. Veterinary medical education, particularly general pathology.

Publications

Dietary n-3 polyunsaturated fatty acids (PUFA) decrease obesity-associated Th17 cell-mediated inflammation during colitis.
Monk JM, Hou TY, Turk HF, Weeks B, Wu C, McMurray DN, Chapkin RS
PLoS One. 7(11):e49739.
Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model.
Fan YY, Monk JM, Hou TY, Callway E, Vincent L, Weeks B, Yang P, Chapkin RS
J Lipid Res. 53(7):1287-95.
Th17 cell accumulation is decreased during chronic experimental colitis by (n-3) PUFA in Fat-1 mice.
Monk JM, Jia Q, Callaway E, Weeks B, Alaniz RC, McMurray DN, Chapkin RS
J Nutr. 142(1):117-24.
Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis.
Monk JM, Kim W, Callaway E, Turk HF, Foreman JE, Peters JM, He W, Weeks B, Alaniz RC, McMurray DN, Chapkin RS
Am J Physiol Gastrointest Liver Physiol. 302(1):G153-67.
A novel shift in estrogen receptor expression occurs as estradiol suppresses inflammation-associated colon tumor formation.
Armstrong CM, Billimek AR, Allred KF, Sturino JM, Weeks BR, Allred CD
Endocr Relat Cancer. 20(4):515-25.
A brief review of ventricular assist devices and a recommended protocol for pathology evaluations.
Carpenter BA, Gonzalez CJ, Jessen SL, Moore EJ, Thrapp AN, Weeks BR, Clubb FJ Jr
Cardiovasc Pathol. 22(5):408-15.
Oil Red O-positive lipid in peritoneal fluid from a horse with a rectal tear.
Brown JS, Johnson MC, Sims WP, Boone LH, Swor TM, Weeks BR
Vet Clin Pathol. 40(2):265-9.
Vertebral osteomyelitis and multiple cutaneous lesions in a dog caused by Nocardia pseudobrasiliensis.
Hilligas J, Van Wie E, Barr J, Russell KE, Perry AL, Weeks BR, Zhang S
J Vet Intern Med. 28(5):1621-5.
Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated mice.
Jia Q, Ivanov I, Zlatev ZZ, Alaniz RC, Weeks BR, Callaway ES, Goldsby JS, Davidson LA, Fan YY, Zhou L, Lupton JR, McMurray DN, Chapkin RS
Br J Nutr. 106(4):519-29.
Role of tumor necrosis factor alpha in disease using a mouse model of Shiga toxin-mediated renal damage.
Lentz EK, Cherla RP, Jaspers V, Weeks BR, Tesh VL
Infect Immun. 78(9):3689-99.
Intrauterine infusion of latency-associated peptide (LAP) during early porcine pregnancy affects conceptus elongation and placental size.
Massuto DA, Hooper RN, Kneese EC, Johnson GA, Ing NH, Weeks BR, Jaeger LA
Biol Reprod. 82(3):534-42.
Coxiella burnetii isolates cause genogroup-specific virulence in mouse and guinea pig models of acute Q fever.
Russell-Lodrigue KE, Andoh M, Poels MW, Shive HR, Weeks BR, Zhang GQ, Tersteeg C, Masegi T, Hotta A, Yamaguchi T, Fukushi H, Hirai K, McMurray DN, Samuel JE
Infect Immun. 77(12):5640-50.
Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice.
Fan YY, Zhan Y, Aukema HM, Davidson LA, Zhou L, Callaway E, Tian Y, Weeks BR, Lupton JR, Toyokuni S, Chapkin RS
J Nutr. 139(7):1328-32.
T cells are essential for bacterial clearance, and gamma interferon, tumor necrosis factor alpha, and B cells are crucial for disease development in Coxiella burnetii infection in mice.
Andoh M, Zhang G, Russell-Lodrigue KE, Shive HR, Weeks BR, Samuel JE
Infect Immun. 75(7):3245-55.
Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediated inflammation and colitis severity.
Monk JM, Turk HF, Fan YY, Callaway E, Weeks B, Yang P, McMurray DN, Chapkin RS
Mediators Inflamm. 2014:917149.
Inhibitory effects of omega-3 fatty acids on injury-induced epidermal growth factor receptor transactivation contribute to delayed wound healing.
Turk HF, Monk JM, Fan YY, Callaway ES, Weeks B, Chapkin RS
Am J Physiol Cell Physiol. 304(9):C905-17.
Assessment of intravenous pbi-shRNA PDX1 nanoparticle (OFHIRNA-PDX1) in yucatan swine.
Jay CM1, Ruoff C2, Kumar P1, Maass H2, Spanhel B2, Miller M2, Arrington A2, Montalvo N2, Gresham V2, Rao DD1, Evans C, Wang Z, Brunicardi FC, Liu SH, Zhou G, Senzer N, Nemunaitis J, King L, Weeks B, Clubb FJ, Fossum TW, Maples PB.
Cancer Gene Ther.. 20(12):683-9.
Integrated microscopy techniques for comprehensive pathology evaluation of an implantable left atrial pressure sensor
A Roberts, K E Trainor, B Weeks, N Jackson, R W Troughton, C J Charles, M T Rademaker, I C Melton, I G Crozier, W Hafelfinger, D E Gutfinger, N L Eigler, W T Abraham, F J Clubb, Jr
J Histotechnol.. 36(1): 17–24.
Dietary Polyunsaturated Fatty Acids Modulate Resistance to Mycobacterium tuberculosis in Guinea Pigs
Christine T. McFarland, Yang-Yi Fan, Robert S. Chapkin, Bradley R. Weeks, David N. McMurray
J Nutr.. 138(11): 2123–2128.
BCG vaccination in the cotton rat (Sigmodon hispidus) infected by the pulmonary route with virulent Mycobacterium tuberculosis.
McFarland CT, Ly L, Jeevan A, Yamamoto T, Weeks B, Izzo A, McMurray D
Tuberculosis (Edinb). 90(4):262-7.
Stathmin I Bifunctional shRNA Effectiveness on Melanoma Progression.
Nicolette Jackson, Kolsie Frazee, Anagha Phadke, Phillip B. Maples, Aaron Roberts, Bradley R. Weeks, Brett P. Giroir and Fred J. Clubb Jr.
Proceedings, CPRIT (Cancer Prevention and Research Institute of Texas) Conference.. CPRIT Conference Proceedings, Nov. 17-19, 2010.
A Low-Cost Digital Particle Image Velocimetry (DPIV) System.
HR Smith, FJ Clubb, Jr., BR Weeks
ASAIO Journal. Annual Meeting ASAIO, Chicago IL.
Role of the Neutrophil Chemorepellent Soluble Dipeptidyl Peptidase IV in Decreasing Inflammation in a Murine Model of Arthritis.
Herlihy SE, Brown ML, Pilling D, Weeks BR, Myers LK, Gomer RH
Arthritis Rheumatology.
Space Environmental Factor Impacts upon Murine Colon Microbiota and Mucosal Homeostasis.
Ritchie LE, Taddeo SS, Weeks BR, Lima F, Bloomfield SA, Azcarate-Peril MA, Zwart SR, Smith SM, Turner ND
PLoS One.
Computational Evaluation of Thrombosis Risk After Ventricular Remodeling with Long-term Mechanical Support
S. L. Jessen, J. D. Horn, A. C. Caruso, F. J. Clubb, Jr., B. R.Weeks
ASAIO Journal (Journal of the American Association for Artificial Internal Organs).
Optimized Rapid Electrolytic Processing of Nitinol Wire Components within Tissue for Paraffin Embedded Histology
A. V. Nguyen, M. T. O’Brien, B. R. Weeks, F. J. Clubb. Jr
ASAIO Journal (Journal of the American Association for Artificial Internal Organs.
Pathology Evaluation and Analysis of Cardiac Leads
HR Smith, SL Jessen, TW Lancon, MT O’Brien, LL Suarez, MD Wilcox, MW Miller, BR Weeks, FJ Clubb, Jr.
ASAIO Journal . ASAIO Annual Meeting, Chicago IL.
Advanced Pathologic Analysis of a Feline Microchip-Associated Fibrosarcoma.
M.T. O’Brien, N.D. Jackson, T. Lancon, H.R. Smith, F.J. Clubb, and B. Weeks.
Veterinary Pathology. Annual Meeting of ACVP, Atlanta GA.
A Method to Increase Radiopacity of PLA Backbone Scaffolds for Preclinical Micro-CT Imaging. (Podium presentation)
SL Lee, SL Jessen, FJ Clubb, Jr., BR Weeks
ASAIO Journal. Annual Meeting ASAIO, Chicago IL.
Analyzing Interactions of Ventricular Assist Devices and Thromboemboli - An in vitro Model (Podium presentation)
SL Jessen, C Martin, BR Weeks, FJ Clubb Jr
ASAIO Journal. Annual Meeting ASAIO, Chicago IL.


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