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Brad Weeks



Phone: (979) 845-0789

Mailstop: 4467

Department: VTPB

Photo of Weeks, Brad


  • Ph.D. Veterinary Pathology, Kansas State University 1988
  • Residency in Veterinary Pathology Anatomic Pathology, Kansas State University 1988
  • D.V.M. Veterinary Medicine, Oklahoma State University 1983
  • B.S. Zoology, Oklahoma State University 1979


  • Licensed to Practice Veterinary Medicine, KS
  • Professor, Dept. of Veterinary Pathobiology,
  • Diplomate, American College of Veterinary Pathologists, (ACVP)
  • Licensed to practice Veterinary Medicine, TX Individual License # 10969:

Scholarly Interests

Diagnostic anatomic pathology; collaborative research of inflammatory and neoplastic gastrointestinal disease, and cardiovascular disease. Veterinary medical education, particularly general pathology.


The non-invasive exfoliated transcriptome (exfoliome) reflects the tissue-level transcriptome in a mouse model of NSAID enteropathy.
Canaan Whitfield-Cargile, Noah Cohen, Kejun He, Ivan Ivanov, Jennifer Goldsby, Ana Chamoun-Emanuelli, Brad Weeks, Laurie Davidson, and Robert Chapkin .
Scientific Reports (Nature Publishing Group). 2017 7(DOI:10.1038/s41598-017-13999-5).
Method for Creating In Vitro Thrombi for Bench-testing of Cardiovascular Medical Devices. Poster Presentation.
KT Ortiz, SL Jessen, FJ Clubb Jr., CN Kaulfus, BR Weeks.
Proceedings of National Veterinary Scholars Symposium. 2017
Estradiol Has Differential Effects on Acute Colonic Inflammation in the Presence and Absence of Estrogen Receptor β Expression
Cameron M Armstrong, Kimberly F Allred, Brad R Weeks, Robert S Chapkin, Clinton D Allred
Digestive Diseases and Sciences. 2017 62(8):1977.
A Method to Increase PLA Scaffold Radiopacity Within Cardiac Vessels. Poster Presentation at ASAIO National Meeting.
AM Ginn, SL Lee, MT O’Brien, BR Weeks, FJ Clubb, Jr
ASAIO Journal (Journal of the American Society for Artificial Internal Organs). 2017
Impact of novel sorghum bran diets on DSS-induced colitis
Lauren E Ritchie, Stella S Taddeo, Brad R Weeks, Raymond J Carroll, Linda Dykes, Lloyd W Rooney, Nancy D Turner
Nutrients. 2017 9(1):330.
Rapidly cycling Lgr5+ stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk
Eunjoo Kim, Laurie A Davidson, Roger S Zoh, Martha E Hensel, Michael L Salinas, Bhimanagouda S Patil, Guddadarangavvanahally K Jayaprakasha, Evelyn S Callaway, Clinton D Allred, Nancy D Turner, Brad R Weeks, Robert S Chapkin
Cell death & disease (Nature Publishing Group). 2016 7(doi:10.1038/cddis.2016.269):e2460.
Computational Evaluation of Thrombosis Risk After Ventricular Remodeling with Long-term Mechanical Support
S. L. Jessen, J. D. Horn, A. C. Caruso, F. J. Clubb, Jr., B. R.Weeks
ASAIO Journal (Journal of the American Association for Artificial Internal Organs). 2016
Optimized Rapid Electrolytic Processing of Nitinol Wire Components within Tissue for Paraffin Embedded Histology
A. V. Nguyen, M. T. O’Brien, B. R. Weeks, F. J. Clubb. Jr
ASAIO Journal (Journal of the American Association for Artificial Internal Organs. 2016
Role of the Neutrophil Chemorepellent Soluble Dipeptidyl Peptidase IV in Decreasing Inflammation in a Murine Model of Arthritis.
Herlihy SE, Brown ML, Pilling D, Weeks BR, Myers LK, Gomer RH
Arthritis Rheumatology. 2015
Advanced Pathologic Analysis of a Feline Microchip-Associated Fibrosarcoma.
M.T. O’Brien, N.D. Jackson, T. Lancon, H.R. Smith, F.J. Clubb, and B. Weeks.
Veterinary Pathology. 2014
Vertebral osteomyelitis and multiple cutaneous lesions in a dog caused by Nocardia pseudobrasiliensis.
Hilligas J, Van Wie E, Barr J, Russell KE, Perry AL, Weeks BR, Zhang S
J Vet Intern Med. 2014 28(5):1621-5.
Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediated inflammation and colitis severity.
Monk JM, Turk HF, Fan YY, Callaway E, Weeks B, Yang P, McMurray DN, Chapkin RS
Mediators Inflamm. 2014 2014(2014):917149.
Assessment of intravenous pbi-shRNA PDX1 nanoparticle (OFHIRNA-PDX1) in yucatan swine.
Jay CM1, Ruoff C2, Kumar P1, Maass H2, Spanhel B2, Miller M2, Arrington A2, Montalvo N2, Gresham V2, Rao DD1, Evans C, Wang Z, Brunicardi FC, Liu SH, Zhou G, Senzer N, Nemunaitis J, King L, Weeks B, Clubb FJ, Fossum TW, Maples PB.
Cancer Gene Ther.. 2013 20(12):683-9.
A brief review of ventricular assist devices and a recommended protocol for pathology evaluations.
Carpenter BA, Gonzalez CJ, Jessen SL, Moore EJ, Thrapp AN, Weeks BR, Clubb FJ Jr
Cardiovasc Pathol. 2013 22(5):408-15.
A novel shift in estrogen receptor expression occurs as estradiol suppresses inflammation-associated colon tumor formation.
Armstrong CM, Billimek AR, Allred KF, Sturino JM, Weeks BR, Allred CD
Endocr Relat Cancer. 2013 20(4):515-25.
Inhibitory effects of omega-3 fatty acids on injury-induced epidermal growth factor receptor transactivation contribute to delayed wound healing.
Turk HF, Monk JM, Fan YY, Callaway ES, Weeks B, Chapkin RS
Am J Physiol Cell Physiol. 2013 304(9):.
Integrated microscopy techniques for comprehensive pathology evaluation of an implantable left atrial pressure sensor
A Roberts, K E Trainor, B Weeks, N Jackson, R W Troughton, C J Charles, M T Rademaker, I C Melton, I G Crozier, W Hafelfinger, D E Gutfinger, N L Eigler, W T Abraham, F J Clubb, Jr
J Histotechnol.. 2013 36(1):17.
Dietary n-3 polyunsaturated fatty acids (PUFA) decrease obesity-associated Th17 cell-mediated inflammation during colitis.
Monk JM, Hou TY, Turk HF, Weeks B, Wu C, McMurray DN, Chapkin RS
PLoS One. 2012 7(11):.
Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model.
Fan YY, Monk JM, Hou TY, Callway E, Vincent L, Weeks B, Yang P, Chapkin RS
J Lipid Res. 2012 53(7):1287-95.
Th17 cell accumulation is decreased during chronic experimental colitis by (n-3) PUFA in Fat-1 mice.
Monk JM, Jia Q, Callaway E, Weeks B, Alaniz RC, McMurray DN, Chapkin RS
J Nutr. 2012 142(1):117-24.
Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis.
Monk JM, Kim W, Callaway E, Turk HF, Foreman JE, Peters JM, He W, Weeks B, Alaniz RC, McMurray DN, Chapkin RS
Am J Physiol Gastrointest Liver Physiol. 2012 302(1):.
Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated mice.
Jia Q, Ivanov I, Zlatev ZZ, Alaniz RC, Weeks BR, Callaway ES, Goldsby JS, Davidson LA, Fan YY, Zhou L, Lupton JR, McMurray DN, Chapkin RS
Br J Nutr. 2011 106(4):519-29.
Oil Red O-positive lipid in peritoneal fluid from a horse with a rectal tear.
Brown JS, Johnson MC, Sims WP, Boone LH, Swor TM, Weeks BR
Vet Clin Pathol. 2011 40(2):265-9.
Stathmin I Bifunctional shRNA Effectiveness on Melanoma Progression.
Nicolette Jackson, Kolsie Frazee, Anagha Phadke, Phillip B. Maples, Aaron Roberts, Bradley R. Weeks, Brett P. Giroir and Fred J. Clubb Jr.
Proceedings, CPRIT (Cancer Prevention and Research Institute of Texas) Conference.. 2010
Role of tumor necrosis factor alpha in disease using a mouse model of Shiga toxin-mediated renal damage.
Lentz EK, Cherla RP, Jaspers V, Weeks BR, Tesh VL
Infect Immun. 2010 78(9):3689-99.
BCG vaccination in the cotton rat (Sigmodon hispidus) infected by the pulmonary route with virulent Mycobacterium tuberculosis.
McFarland CT, Ly L, Jeevan A, Yamamoto T, Weeks B, Izzo A, McMurray D
Tuberculosis (Edinb). 2010 90(4):262-7.
Intrauterine infusion of latency-associated peptide (LAP) during early porcine pregnancy affects conceptus elongation and placental size.
Massuto DA, Hooper RN, Kneese EC, Johnson GA, Ing NH, Weeks BR, Jaeger LA
Biol Reprod. 2010 82(3):534-42.
Coxiella burnetii isolates cause genogroup-specific virulence in mouse and guinea pig models of acute Q fever.
Russell-Lodrigue KE, Andoh M, Poels MW, Shive HR, Weeks BR, Zhang GQ, Tersteeg C, Masegi T, Hotta A, Yamaguchi T, Fukushi H, Hirai K, McMurray DN, Samuel JE
Infect Immun. 2009 77(12):5640-50.
Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice.
Fan YY, Zhan Y, Aukema HM, Davidson LA, Zhou L, Callaway E, Tian Y, Weeks BR, Lupton JR, Toyokuni S, Chapkin RS
J Nutr. 2009 139(7):1328-32.
Dietary Polyunsaturated Fatty Acids Modulate Resistance to Mycobacterium tuberculosis in Guinea Pigs
Christine T. McFarland, Yang-Yi Fan, Robert S. Chapkin, Bradley R. Weeks, David N. McMurray
J Nutr.. 2008 138(11):2123.
A Method to Increase Radiopacity of PLA Backbone Scaffolds for Preclinical Micro-CT Imaging. (Podium presentation)
SL Lee, SL Jessen, FJ Clubb, Jr., BR Weeks
ASAIO Journal.
Analyzing Interactions of Ventricular Assist Devices and Thromboemboli - An in vitro Model (Podium presentation)
SL Jessen, C Martin, BR Weeks, FJ Clubb Jr
ASAIO Journal.
Pathology Evaluation and Analysis of Cardiac Leads
HR Smith, SL Jessen, TW Lancon, MT O’Brien, LL Suarez, MD Wilcox, MW Miller, BR Weeks, FJ Clubb, Jr.
ASAIO Journal .
Space Environmental Factor Impacts upon Murine Colon Microbiota and Mucosal Homeostasis.
Ritchie LE, Taddeo SS, Weeks BR, Lima F, Bloomfield SA, Azcarate-Peril MA, Zwart SR, Smith SM, Turner ND
PLoS One.
A Low-Cost Digital Particle Image Velocimetry (DPIV) System.
HR Smith, FJ Clubb, Jr., BR Weeks
ASAIO Journal.

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