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Scott Dindot

Associate Professor


Phone: (979) 458-4725

Mailstop: 4467

Department: VTPB

Photo of Dindot, Scott


  • Ph.D. Genetics, Texas A&M University 2003
  • B.S. Molecular and Cell Biology, Texas A&M University 1999

Scholarly Interests

The overarching themes of research in my laboratory are to understand the genetic and epigenetic basis of disease, with an emphasis on neurological disorders associated with genomic imprinting, a naturally occurring phenomenon that leads to the differential expression of alleles in a parent-of-origin dependent manner. We are interested in understanding why and how genes are imprinted, the function of imprinting in the brain, and the development of new therapies to treat imprinted disorders.


Identification of a candidate mutation in the COL1A2 gene of a Chow Chow with osteogenesis imperfecta.
E M Quist, R Doan, R R Pool, B F Porter, D L Bannasch, S V Dindot
The Journal of heredity. 2017
Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome.
Nycole A Copping, Sarah G B Christian, Dylan J Ritter, M Saharul Islam, Nathalie Buscher, Dorota Zolkowska, Michael C Pride, Elizabeth L Berg, Janine M LaSalle, Jacob Ellegood, Jason P Lerch, Lawrence T Reiter, Jill L Silverman, Scott V Dindot
Human molecular genetics. 2017 26(20):3995-4010.
Genomic imprinting does not reduce the dosage of UBE3A in neurons.
Paul R Hillman, Sarah G B Christian, Ryan Doan, Noah D Cohen, Kranti Konganti, Kory Douglas, Xu Wang, Paul B Samollow, Scott V Dindot
Epigenetics & chromatin. 2017 10:27.
Identification of copy number variants in horses.
Doan R, Cohen N, Harrington J, Veazey K, Juras R, Cothran G, McCue ME, Skow L, Dindot SV
Genome Res. 2012 22(5):899-907.
Intrathecal injection of helper-dependent adenoviral vectors results in long-term transgene expression in neuroependymal cells and neurons.
Dindot S, Piccolo P, Grove N, Palmer D, Brunetti-Pierri N
Hum Gene Ther. 2011 22(6):745-51.
Epigenetic profiling at mouse imprinted gene clusters reveals novel epigenetic and genetic features at differentially methylated regions.
Dindot SV, Person R, Strivens M, Garcia R, Beaudet AL
Genome Res. 2009 19(8):1374-83.

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