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Graduate

The courses listed below are from the 2014-2015 Graduate Catalog

605. Systemic Veterinary Physiology I. (5-0). Credit 5. Aspects of cellular physiology, physiology of excitable membranes, physiology of body fluids, neurophysiology, and the physiology of smooth, cardiac and skeletal muscle; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies. Prerequisite: Graduate classification.

606. Systemic Veterinary Physiology II. (5-0). Credit 5. In-depth study covering cardiovascular, respiratory, renal physiology, gastrointestinal and endocrine physiology; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies. Prerequisite: VTPP 605.

610. Physiology I. (5-2). Credit 6. Introduction to physiology: cell physiology, cell signaling, cell cycle, body fluids, translocation of materials, membrane potentials, neurophysiology, autonomic nervous system, thermoregulation, cardiovascular, and muscle physiology. Prerequisites: Enrollment in MS/PhD program in Veterinary Physiology and Pharmacology; approval of instructor.

612. Physiology II. (5-2). Credit 6. Blood and lymph, respiration, renal physiology, and acid-based balance, gastrointestinal physiology, metabolism, endocrinology, and reproduction. Prerequisites: Enrollment in MS/PhD program in Veterinary Physiology and Pharmacology; approval of instructor.

623. Biomedical Physiology I. (3-2). Credit 4. Physiological principles, review of cellular physiology, and development of an understanding of the nervous system and muscle, cardiovascular, and respiratory physiology; clinical applications related to organ systems. Prerequisites: Graduate classification; BICH 410 and VIBS 305 recommended.

625. Pharmacology. (3-0). Credit 3. Introduction to pharmacokinetics and pharmacodynamics; survey of major pharmaceutical classes; uses, mechanisms of action and adverse reactions of selected agents. Prerequisites: Graduate classification; VTPP 423 or approval of instructor.

627. Biomedical Physiology II. (3-0). Credit 3. Continuation of VTPP 623 Fluid balance and acid-base balance; development of an understanding of renal, gastrointestinal, endocrine and reproductive physiology using human and other mammalian models; clinical applications related to organ systems. Prerequisites: Graduate classification; VTPP 623.

628. Pharmacology I. (4-2). Credit 5. Pharmacokinetics, pharmacodynamics, CNS pharmacology, autonomic pharmacology, antineoplastic agents, immunopharmacology, recombinant products, fluid and electrolyte therapy, diuretics, pharmacology of the integument. Prerequisite: Approval of instructor.

629. Pharmacology II. (2-2). Credit 3. Antimicrobials, endocrine pharmacology, eicosanoids, anti-inflammatory agents, respiratory pharmacology, anticoagulants and hematinics, GI pharmacology, cardiovascular pharmacology. Prerequisite: Approval of instructor.

630. Pharmacology/Toxicology. (2-2). Credit 3. Management and treatment of toxicosis, antidotal pharmacology, toxic plants, mycotoxins, chemical toxicants, metals, euthanasia. Prerequisite: Approval of instructor.

634. Physiology for Bioengineers I. (3-3). Credit 4. Cellular anatomy, cellular physiology and biochemistry; systems analysis of digestive, endocrine and musculoskeletal system function including information related to gross anatomy, histology and disease states; quantitative aspects of physiology and engineering applications to clinical medicine. Prerequisite: Biomedical Engineering major or approval of instructor. Course Descriptions/Veterinary Physiology and Pharmacology 641

635. Physiology for Bioengineers II. (3-3). Credit 4. A systems analysis of nervous, cardiovascular, respiratory and urinary function including information related to gross anatomy, histology and disease states; quantitative aspects of physiology and engineering applications to clinical medicine. Prerequisite: VTPP 634.

638. Analysis of Genomic Signals. (2-2). Credit 3. Overview of current high throughput technology for data acquisition and analysis of genomic signals (e.g., mRNA or proteins); emphasis on microarray technology, methods for analyzing microarray data, and approaches to model the underlying phenomena from the systems biology perspective. Prerequisites: BIOL 451 or GENE 320/BIMS 320 or equivalent; STAT 651 or equivalent; or approval of instructor.

651. Epigenetics & Systems Physiology. (3-0). Credit 3. Journal club format focusing on epigenetic regulation of physiological systems; assignment of papers from primary literature and weekly oral presentations detailing opinions on research; emphasis on fundamental concepts in epigenetics, physiology and the molecular techniques employed to address research hypotheses, discussions of scientific ethics and fraud. Prerequisite: Graduate classification.

652. Fetal and Embryo Physiology. (3-0). Credit 3. Introduction to the physiologic processes driving embryonic development and pregnancy; focus on embryo implantation, establishment of the placenta, development of the fetal circulatory systems and the molecular processes governing embryo differentiation and development; special emphasis on the major organ systems affected by pediatric disease and on the actions of teratogens. Prerequisites: Graduate classification.

653. Endocrinology. (3-3). Credit 4. Physiology, biochemistry and pharmacology of the endocrines. Laboratory emphasizes a number of classical experiments with clinical application. Prerequisite: Approval of instructor.

654. Molecular Endocrinology. (3-0). Credit 3. Structure-function relationships of hormones, their receptors and biologic activities. Prerequisites: VTPP 653 or BIOL 649 and BICH 410 or equivalent or approval of instructor.

655. Vascular Physiology. (4-0). Credit 4. Structure and function of blood vessels and vascular beds; molecular and cell biology of endothelium and vascular smooth muscle; microcirculation; capillary exchange; regulation of blood flow by local, neural and humoral signals. Prerequisite: MPHY 901 or approval of department head.

656. Physiology of the Heart. (4-0). Credit 4. Structure and function of the heart; molecular and cell biology of cardiac myocytes; electrophysiology of myocardium, pacemaker cells and conducting tissue; cardiac mechanics; control of cardiac performance; coronary circulation. Prerequisite: MPHY 901 or MPHY 604 or approval of department head.

657. Cardiovascular Physiology. (3-3). Credit 4. Physiological considerations of the circulatory system including general and integrative aspects of the heart and blood vessels. Prerequisites: Approval of instructor.

659. Gamete and Embryo Physiology. (2-2). Credit 3. Physiology of gametes and preimplantation embryos in livestock and laboratory animals; oocyte growth and maturation in-vivo and in-vitro, fertilization in-vivo and in-vitro, embryo transfer, cryopreservation, nuclear transfer, chimera formation, gene transfer.

667. Current Topics in Pharmacology. (3-0). Credit 3. Discussions of literature regarding topics of current research interest; physiochemical or physiologic effects of drugs at sites from molecular to whole body. Prerequisite: Approval of instructor.

673. Metabolic and Detoxication Mechanisms. (3-0). Credit 3. Fate of foreign compounds; their inhibitory and antagonistic action toward normal metabolic processes of the animal body. Prerequisites: BICH 603; approval of instructor and department head.

675. Industrial and Environmental Toxicology. (3-0). Credit 3. Fundamentals of toxicology and risk assessment; effects of selected classes of hazardous chemicals encountered in the workplace or environment on human health will be considered. Prerequisite: Approval of instructor.

676. Genetic and Molecular Toxicology. (3-0). Credit 3. Mechanisms of toxicant-induced target organ toxicity with emphasis on molecular control of mammalian and cell growth differentiation. Prerequisite: Graduate course in cell biology and biochemistry.

677. Fluorescence Detection: Steady State, Time Resolved and Imaging. (4-0). Credit 4. Fluorescence spectroscopy and confocal/multiphoton microscopy in research; intro of pharmacology, life science, and physical science students to fluorophores, anisotropy, ligand binding, energy transfer, cytometry, lifetime imaging, correlation spectroscopy, immunocytochemistry, and image analysis with an emphasis on instrumental/sample artifacts, fluorescence application, literature evaluation, and communication of rationales to other scientists. Prerequisite: General chemistry and biology course.

681. Seminar. (1-0). Credit 1. Review and discussion of current scientific work in physiology and related subjects. Prerequisite: Approval of department head.

685. Directed Studies. Credit 1 to 4 each semester. Problems in physiology, pharmacology or toxicology.Prerequisite: Approval of instructor.

689. Special Topics in... Credit 1 to 4. Selected topics in an identified area of veterinary physiology and pharmacology. May be repeated for credit. Prerequisite: Approval of instructor.

690. Theory of Research. (3-0). Credit 3. Theory and design of research related to current biomedical problems especially those involving study of animal disease; philosophical perspectives underlying his- torical advances in research pertaining to the study, prevention and treatment of disease. Prerequisite: Graduate classification. Cross-listed with VIBS 690 and VPAT 690.

691. Research. Credit 1 or more each semester. Original investigations in veterinary physiology, pharma- cology or toxicology to be submitted by writing of thesis or dissertation as partial fulfillment for MS or PhD degree. Prerequisite: Approval of department head.

910. Physiology I. (5-2). Credit 6. Introduction to physiology: cell physiology, cell signaling, cell cycle, body fluids, translocation of materials, membrane potentials, neurophysiology, autonomic nervous sys- tem, thermoregulation, cardiovascular, and muscle physiology. Prerequisite: Enrollment in first year of professional curriculum.

912. Physiology II. (5-2). Credit 6. Blood and lymph, respiration, renal physiology, and acid-base balance, gastrointestinal physiology, metabolism, endocrinology, and reproduction. Prerequisite: Enrollment in the first year of professional curriculum.

924. Pharmacology/Toxicology I. (4-2). Credit 5. Pharmacokinetics, pharmacodynamics, CNS pharma- cology, autonomic pharmacology, antineoplastic agents, immunopharmacology, recombinant products, fluid and electrolyte therapy, diuretics, pharmacology of the integument. Prerequisite: Enrollment in the second year of professional curriculum.

925. Pharmacology/Toxicology II. (2-2). Credit 3. Antimicrobials, endocrine pharmacology, eicosanoids, antiinflammatory agents, respiratory pharmacology, anticoagulants and hematinics, GI pharmacology, cardiovascular pharmacology. Prerequisite: Enrollment in the second year of professional curriculum.

926. Pharmacology/Toxicology III. (2-2). Credit 3. Management and treatment of toxicoses, antidotal pharmacology, toxic plants, mycotoxins and mycotoxicoses, chemical toxicants, metals, euthanasia. Pre- requisite: Enrollment in the second year of professional curriculum.

948. Didactic Elective in Veterinary Physiology and Pharmacology. Credit 1 to 12. Elective course in physiology and pharmacology for professional students who wish to supplement required curriculum. May be repeated for credit. Prerequisite: Enrollment in the fourth year of professional curriculum.

985. Directed Studies. Credit 1 to 4. Directed, individual study of selected problems in physiology, phar- ology or toxicology. May be repeated for credit. Prerequisite: Approval of instructor and department head.