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Friedhelm Schroeder

Professor

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Phone: (979) 862-1433

Mailstop: 4466

Department: VTPP

Photo of Schroeder, Friedhelm

Education

  • Postdoctoral Biological Chemistry, Washington University Medical 1976
  • PhD Biochemistry, Michigan State University 1973
  • BS Chemistry Mathematics, University of Pittsburgh 1970

Scholarly Interests

Intracellular lipid transfer proteins; lipid metabolism; multiphoton imaging of intracellular lipid transport and targeting in living cells and tissues of gene targeted animals.

Publications

Endocthelial nitric oxide synthase protein distribution in endothelial cells along the coronary vascular tree
Heaps CL, Bray JF, McIntosh AL, Schroeder F, Israel JH
Microcirculation. 2016
Duplicated bovine NK-lysin family members exhibit antimicrobial activities against members of the bovine respiratory disease complex
Chen J, Yang C, Tizioto P, Huan H, Lee MOK, Payne R, Lawhon S, Schroeder F, Taylor JF, Womack JE
Plos Pathogens. 2016 DOI:10.1371/journal.pone.0158882:DOI:10.1371/journal.pone.0158882.
Female mice are resistant to FABP1 gene ablation-induced alterations in brain endocannabinoid levels
Martin GG, Chung S, Landrock D, Landrock KK, Dangott LJ, Peng X, Kaczocha M, Murphy EJ, Kier AB, and Schroeder F
Lipids. 2016 51:1007-1020.
Fatty acid binding protein-1 (FABP1) and the human FABP1 T94A variant: Roles in the endocannabinoid system and dyslipidemias
Schroeder, F., McIntosh, A. L., Martin, G. G., Huang, H., Landrock D., Chung, S., Landrock, K. K., Dangott, L. J., Li, S., Kaczocha, M., Murphy, E. J., Atshaves, B. P., and Kier, A. B.
Lipids. 2016 51:655-676.
FABP1: a novel hepatic endocannabinoid and cannabinoid binding protein
Huang H, McIntosh A L, Martin GG, Landrock D, Chung S, Landrock KK, Dangott LJ, Li S, Kier AB, Schroeder F.
Biochemistry. 2016 55:5243-5255.
FABP1 gene ablation impacts brain endocannabinoid system in male mice
Martin, G., Chung, S., Landrock D., Landrock, K. K., Huang, H., Dangott, L. J., Peng, X., Kaczocha, M., Seeger, D. R., Murphy, E. J., Golovko, M. Y., Kier, A. B., and Schroeder, F.
J Neurochem. 2016 138:407-422.
Interactions and functional studies of Rotavirus NSP4 with caveolin-1, immunophilins, and cholesterol
Yakshe KA, Gibbons TF, Schroeder F, Lopez S, Ball JM
Virology. 2016
Relative contributions of L-FABP, SCP-2/SCPx, or both to hepatic biliary phenotype of female mice
Martin GG, Landrock D, Landrock KK, Howles P, Atshaves BP, Kier AB, Schroeder F
Arch Biochem Biophys. 2015
Duplicated bovine NK-lysin family members exhibit antimicrobial activities against members of the bovine respiratory disease complex
Chen J, Yang C, Tizioto P, Huan H, Lee MOK, Payne R, Lawhon S, Schroeder F, Taylor JF, Womack JE
PLos Pathogens. 2015
SCP-2/SCP-x gene ablation exacerbates high-cholesterol induced hepatic lipid accumulation
Klipsic D, Landrock D, Martin GG, McIntosh AL, Landrock KK, Mackie JT, Schroeder F, Kier AB
Am J Physiol Gastrointest Liver Physiol. 2015 309:G387-G399.
Loss of L-FABP, SCP-2/SCPx, or both induces hepatic lipid accumulation in female mice
Martin GG, Atshaves BP, Landrock KK, Landrock D, Schroeder F, Kier AB
Arch Biochem Biophys. 2015 580(580):41-49.
Human liver fatty acid binding protein (L-FABP) T94A variant enhances cholesterol uptake
Huang H, McIntosh AL, Martin GG, Landrock KK, Landrock D, Storey SM, Gupta S, Atshaves BP, Kier AB, Schroeder F
Biochim Biophys Acta. 2015 1851(1851):946-955.
Ablating L-FABP in SCP-2/SCP-x null mice impairs bile acid metabolism and biliary HDL-cholesterol secretion
Martin, GG, Atshaves, BP, Landrock, KK, Landrock, D, Storey, SM, Howles, PN, Kier, AB, Schroeder, F
Am J Physiol Gastrointest Liver Physiol. 2014
Human FABP1 T94A variant impacts fatty acid metabolism and PPAR activation in cultured human primary hepatocytes
McIntosh, A.L., Huang, H., Storey, S.M., Landrock, K.K., Landrock, D., Petrescu, A.D., Gupta, S., Atshaves, B.P., Kier, A.B., Schroeder, F.
Am. J. Physiol. Gastrointest. Liver Physiol. . 2014 307:G164-G176.
Structural and functional interaction of fatty acids with human liver fatty acid binding protein (L-FABP) T94A variant
Huang, H., McIntosh, A.L., Martin, G.G., Landrock, K.K., Landrock, D., Gupta, S., Atshaves, B.P., Kier, A.B., and Schroeder, F.
FEBS J. 2014 281(281):2266-2283.
Inhibitors of fatty acid synthesis induce PPAR-regulated fatty acid -oxidative enzymes: synergistic roles of L-FABP and glucose
Huang H, McIntosh AL, Martin GG, Petrescu AD, Landrock K, Landrock D, Kier AB, Schroeder F.
PPAR Research . 2013
Impact of L-FABP and glucose on polyunsaturated fatty acid induction of PPAR regulated -oxidative enzymes
Petrescu AD, Huang H, Martin GG, McIntosh AL, Storey SM, Landrock D, Kier AB, Schroeder F.
Am J Physiol Gastrointest and Liver Phys . 2013 301:G241-G256.
Human L-FABP T94A variant alters structure, stability, and interaction with fibrates
Martin GG, McIntosh AL, Huang H, Gupta S, Atshaves BP, Kier AB, Schroeder F.
Biochemistry. 2013 52(52):9347-9357.
Mutational analysis of the rotavirus NSP4 enterotoxic domain that binds to caveolin-1
Ball JM, Schroeder ME, Williams CV, Schroeder F, Parr RD.
Virology Journal . 2013 10(10):336.
L-FABP interacts with HNF4alpha
McIntosh AL, Petrescu AD, Hostetler HA, Kier AB, Schroeder F
FEBS Letters. 2013 587(587):3787-3791.
High glucose potentiates L-FABP-mediated fibrate induction of PPAR in mouse hepatocytes
Petrescu AD, McIntosh AL, Storey SM, Huang H, Martin GG, Landrock D, Kier AB, Schroeder F
Biochim Biophys Acta. 2013 1831(1831):1412-1425.
L-FABP gene ablation exacerbates weight gain in high-fat fed female mice
McIntosh AL, Atshaves BP, Landrock D, Landrock KK, Martin GG, Storey SM, Kier AB, Schroeder F
Lipids . 2013 48(48):435-448.
Fabp1 gene ablation inhibits high fat diet-induced increase in brain endocannabinoids
Martin GG, Landrock D, Chung S, Dangott LJ, Seeger DR, Murphy EJ, Golovko MY, Kier AB, and Schroeder F
J Neurochem.


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