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Charles Long

Professor

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Phone: (979) 845-2331

Mailstop: 4466

Department: VTPP

Photo of Long, Charles

Education

  • Post Doctoral Training Gamete and Embryo Physiology, ARS-USDA 1998
  • PHD Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst 1996
  • MS Department of Animal Science, University of Missouri, Columbia 1989
  • BS Department of Animal Science, University of Missouri, Columbia 1986

Scholarly Interests

developmental biology, gamete and embryo physiology, embryonic stem cells, assisted reproductive technologies, animal transgenics, somatic cell nuclear transfer, epigenetics, biomedical models, disease resistance

Publications

Expression of Porcine Fusion Protein IRF7/3(5D) Efficiently Controls Foot-and-Mouth Disease Virus Replication.
Ramírez-Carvajal L, Díaz-San Segundo F, Hickman D, Long CR, Zhu J, Rodríguez LL, de Los Santos T
J Virol. 2014 88(19):11140-53.
Genome edited sheep and cattle.
Proudfoot C, Carlson DF, Huddart R, Long CR, Pryor JH, King TJ, Lillico SG, Mileham AJ, McLaren DG, Whitelaw CB, Fahrenkrug SC
Transgenic Res. 2014
Sustained expression of insulin by a genetically engineered sertoli cell line after allotransplantation in diabetic BALB/c mice.
Kaur G, Thompson LA, Pasham M, Tessanne K, Long CR, Dufour JM
Biol Reprod. 2014 90(5):109.
Reshaping the transcriptional frontier: epigenetics and somatic cell nuclear transfer.
Long CR, Westhusin ME, Golding MC
Mol Reprod Dev. 2014 81(2):183-93.
Transgenic sheep generated by lentiviral vectors: safety and integration analysis of surrogates and their offspring.
Cornetta K, Tessanne K, Long C, Yao J, Satterfield C, Westhusin M
Transgenic Res. 2013 22(4):737-45.
Efficient TALEN-mediated gene knockout in livestock.
Carlson DF, Tan W, Lillico SG, Stverakova D, Proudfoot C, Christian M, Voytas DF, Long CR, Whitelaw CB, Fahrenkrug SC
Proc Natl Acad Sci U S A. 2012 109(43):17382-7.
Cryopreservation of in vitro produced bovine embryos: Effects of lipid segregation and post-thaw laser assisted hatching.
Pryor J, Looney CR, Romo S, Kraemer DC and Long CR
Theriogenology. 2011 75(75):24-33.
Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine development.
Golding MC, Williamson GL, Stroud TK, Westhusin ME, Long CR
Mol Reprod Dev. 2011 78(5):306-17.
Embryo production and possible species preservation by nuclear transfer of somatic cells isolated from bovine semen.
Liu J, Westhusin M, Long C, Johnson G, Burghardt R, Kraemer D
Theriogenology. 2010 74(9):1629-35.
Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A.
Porada CD, Sanada C, Long CR, Wood JA, Desai J, Frederick N, Millsap L, Bormann C, Menges SL, Hanna C, Flores-Foxworth G, Shin T, Westhusin ME, Liu W, Glimp H, Zanjani ED, Lozier JN, Pliska V, Stranzinger G, Joerg H, Kraemer DC, Almeida-Porada G
J Thromb Haemost. 2010 8(8):276-285.
Viral particles of endogenous betaretroviruses are released in the sheep uterus and infect the conceptus trophectoderm in a transspecies embryo transfer model.
Black SG, Arnaud F, Burghardt RC, Satterfield MC, Fleming JA, Long CR, Hanna C, Murphy L, Biek R, Palmarini M, Spencer TE
J Virol. 2010 84(18):9078-85.
Applications of RNA interference-based gene silencing in animal agriculture.
Long CR, Tessanne KJ, Golding MC
Reprod Fertil Dev. 2010 22(1):47-58.
Evaluation of culture systems for attachment and proliferation of epithelial cells cultured from ovine semen.
Liu J, Westhusin M, Johnson G, Raudsepp T, Chowdhary B, Burghardt R, Long C, Kraemer D
Anim Reprod Sci. 2009 115(1-4):49-57.
Laser Assisted Hatching in Bovine In Vitro Produced Embryos to Improve Pregnancy Rates
Charles R. Long
Acta Scientiae Veterinariae Supplement . 2008 2(2):311-317.
Assessment of canine oocyte viability after transportation and storage under different conditions.
Hanna C, Long C, Hinrichs K, Westhusin M, Kraemer D
Anim Reprod Sci. 2008 105(3-4):451-6.
Identification, amplification and characterization of miR-17-92 from canine tissue.
Boggs RM, Moody JA, Long CR, Tsai KL, Murphy KE
Gene. 2007 404(1-2):25-30.
Suppression of prion protein in livestock by RNA interference.
Golding MC, Long CR, Carmell MA, Hannon GJ, Westhusin ME
Proc Natl Acad Sci U S A. 2006 103(14):5285-90.
Epigenetic and genomic imprinting analysis in nuclear transfer derived Bos gaurus/Bos taurus hybrid fetuses.
Dindot SV, Farin PW, Farin CE, Romano J, Walker S, Long C, Piedrahita JA
Biol Reprod. 2004 71(2):470-8.
New commercial opportunities for advanced reproductive technologies in horses, wildlife and companion animals.
Long CR, Walker SC, Tang RT, Westhusin ME
Theriogenology. 2003 59(59):139-149.
Cloning to reproduce desired genotypes.
Westhusin ME, Long CR, Shin T, Hill JR, Looney CR, Pryor JH, Piedrahita JA
Theriogenology. 2001 55(1):35-49.
Evidence for placental abnormality as the major cause of mortality in first-trimester somatic cell cloned bovine fetuses.
Hill JR, Burghardt RC, Jones K, Long CR, Looney CR, Shin T, Spencer TE, Thompson JA, Winger QA, Westhusin ME
Biol Reprod. 2000 63(6):1787-94.
Birth of piglets after transfer of embryos cryopreserved by cytoskeletal stabilization and vitrification.
Dobrinsky JR, Pursel VG, Long CR, Johnson LA
Biol Reprod. 2000 62(62):564-570.
Development rates of male bovine nuclear transfer embryos derived from adult and fetal cells.
Hill JR, Winger QA, Long CR, Looney CR, Thompson JA, Westhusin ME
Biol Reprod. 2000 62(5):1135-40.
Initiation and organization of events during the first cell cycle in mammals: Applications in cloning
Fissore RA, Long CR, Duncan RP and Robl JM
Cloning. 1999 1(1):89-100.
In vitro production of pig embryos: culture media and boar comparisons.
Long CR, Dobrinsky JR and Johnson LA
Theriogenology. 1999 51(51):1375-1390.


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