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Annie Newell-Fugate

Assistant Professor

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Phone: (979) 845-1744

Mailstop: 4466

Department: VTPP

Photo of Newell-Fugate, Annie

Education

  • PhD reproductive endocrinology, University of Illinois at Urbana-Champaign 2012
  • MSc wildlife reproductive physiology, University of Pretoria 2008
  • DVM veterinary medicine, NCSU CVM 2004
  • BS Biology, UNC-Chapel Hill 2000

Job Functions

  • Teaching undergraduate physiology (VTPP 423) in the BIMS major and research focused on reproductive endocrinology and obesity.

Scholarly Interests

Polycystic ovary syndrome (PCOS) is the most prevalent reproductive endocrine disorder in women and results in a substantial financial burden to the American healthcare system. PCOS is characterized by an/oligoovulation, polycystic ovaries, and hyperandrogenism. PCOS patients are also at risk for the development of metabolic syndrome, type 2 diabetes, and cardiovascular disease. My laboratory focuses on the effects of obesity, hyperinsulinemia, and insulin resistance on androgen steroidogenesis and the interrelationship between androgens and insulin signaling in steroidogenic tissues and adipose tissue. An additional focus of my laboratory is the effect of novel fat sources on metabolic and reproductive function in the context of obesity. Using cell culture and rodent and porcine models, my research program examines the direct and indirect effects of obesity and resulting hyperandrogenemia on steroidogenesis and reproductive function in females. I also have a strong interest in wildlife and zoo animal endocrinology and reproductive physiology. In the past, I have conducted endocrine based research projects on the Pallas' Cat and African Wild Dog. My current research examines the effect of the introduction of novel pheromones versus novel animals on fecal steroid metabolite concentrations, behavior, and estrous cyclicity in captive, female Red River Hogs. I am also working with zoo-based collaborators to develop an eletroejaculation and artificial insemination protocol for Suidae (pig) and Tayassuidae (peccary) species and am engaged in a retrospective characterization of reproductive tract lesions in pigs and peccaries in relation to age, parity and contraceptive use.

Publications

Effects of coconut oil on glycemia, inflammation, and urogenital microbial parameters in female Ossabaw mini-pigs.
Annie E Newell-Fugate, Katherine Lenz, Cassandra Skenandore, Romana A Nowak, Bryan A White, Andrea Braundmeier-Fleming
PloS one. 2018 12(7):e0179542.
Evaluation of a commercially available radioimmunoassay and enzyme immunoassay for the analysis of progesterone and estradiol and the comparison of two extraction efficiency methods.
C S Skenandore, A Pineda, J M Bahr, A E Newell-Fugate, F C Cardoso
Domestic animal endocrinology. 2018 60:61-66.
The role of sex steroids in white adipose tissue adipocyte function.
A E Newell-Fugate
Reproduction (Cambridge, England). 2018 153(4):R133-R149.
Effects of Obesity and Metabolic Syndrome on Steroidogenesis and Folliculogenesis in the Female Ossabaw Mini-Pig.
Annie E Newell-Fugate, Jessica N Taibl, Mouhamad Alloosh, Michael Sturek, Janice M Bahr, Romana A Nowak, Rebecca L Krisher
PloS one. 2018 10(6):e0128749.
Effects of diet-induced obesity on metabolic parameters and reproductive function in female Ossabaw minipigs.
Annie E Newell-Fugate, Jessica N Taibl, Sherrie G Clark, Mouhamad Alloosh, Michael Sturek, Rebecca L Krisher
Comparative medicine. 2018 64(1):44-9.
Seasonal changes in steroid hormone profiles, body weight, semen quality, and the reproductive tract in captive African wild dogs (Lycaon pictus) in South Africa.
Annie E Newell-Fugate, Johan O Nöthling, Henk J Bertschinger
General and comparative endocrinology. 2018 178(2):272-81.
Intrapartum uterine rupture with coincidental uterine adenomyosis in an African wild dog (Lycaon pictus).
Annie Newell-Fugate, Emily Lane
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2018 40(4):791-5.
Periaortic haemangiosarcoma in an African wild dog (Lycaon pictus).
A Newell-Fugate, E Lane
Journal of the South African Veterinary Association. 2018 80(2):108-10.
Seminal and endocrine characteristics of male Pallas' Cats (Otocolobus manul) maintained under artificial lighting with simulated natural photoperiods.
Annie Newell-Fugate, Suzanne Kennedy-Stoskopf, Janine L Brown, Jay F Levine, William F Swanson
Zoo biology. 2018 26(3):187-99.
Assessment of Viral Presence in Semen and Reproductive Function of Frozen-Thawed Spermatozoa from Pallas' Cats (Otocolobus manul) Infected with Feline Herpesvirus.
Swanson, W., Maggs, D., Clarke, H., Newell, A., Bond, J., Bateman, H., Kennedy-Stoskopf, S
Journal of Zoo and Wildlife Medicine. 2006 37(3):336-346.


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