{"id":19590,"date":"2023-04-12T08:57:55","date_gmt":"2023-04-12T13:57:55","guid":{"rendered":"https:\/\/vetmed.tamu.edu\/news\/?p=19590"},"modified":"2023-04-12T08:58:18","modified_gmt":"2023-04-12T13:58:18","slug":"fathers-alcohol-linked-to-offspring-defects","status":"publish","type":"post","link":"https:\/\/vetmed.tamu.edu\/news\/press-releases\/fathers-alcohol-linked-to-offspring-defects\/","title":{"rendered":"Father&#8217;s Alcohol Consumption Before Conception Linked To Brain And Facial Defects In Offspring"},"content":{"rendered":"\n<p><em><strong>Fetal alcohol syndrome-related craniofacial differences could be seen in offspring born to fathers who regularly consumed alcohol to the legal limit.<\/strong><\/em><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/vetmed.tamu.edu\/news\/wp-content\/uploads\/sites\/9\/2023\/04\/Golding2-1024x768.jpg\" alt=\"Dr. Michael Golding\" class=\"wp-image-19592\" width=\"550\" srcset=\"https:\/\/vetmed.tamu.edu\/news\/wp-content\/uploads\/sites\/9\/2023\/04\/Golding2-1024x768.jpg 1024w, https:\/\/vetmed.tamu.edu\/news\/wp-content\/uploads\/sites\/9\/2023\/04\/Golding2-300x225.jpg 300w, https:\/\/vetmed.tamu.edu\/news\/wp-content\/uploads\/sites\/9\/2023\/04\/Golding2-768x576.jpg 768w, https:\/\/vetmed.tamu.edu\/news\/wp-content\/uploads\/sites\/9\/2023\/04\/Golding2-640x480.jpg 640w, https:\/\/vetmed.tamu.edu\/news\/wp-content\/uploads\/sites\/9\/2023\/04\/Golding2-1200x900.jpg 1200w, https:\/\/vetmed.tamu.edu\/news\/wp-content\/uploads\/sites\/9\/2023\/04\/Golding2-150x113.jpg 150w, https:\/\/vetmed.tamu.edu\/news\/wp-content\/uploads\/sites\/9\/2023\/04\/Golding2.jpg 1440w\" sizes=\"(max-width: 639px) 98vw, (max-width: 1199px) 64vw, 770px\" \/><figcaption class=\"wp-element-caption\">Dr. Michael Golding<\/figcaption><\/figure>\n<\/div>\n\n\n<p>According to the U.S. Surgeon General, women should not drink alcoholic beverages during pregnancy because of the risk of birth defects in their unborn child. However, research at Texas A&amp;M University now demonstrates that a father\u2019s alcohol consumption also links to growth defects that affect the development of his offspring\u2019s brain, skull, and face.&nbsp;<\/p>\n\n\n\n<p>Research investigating fetal alcohol syndrome (FAS) exclusively examines maternal alcohol exposure.<\/p>\n\n\n\n<p>However, because men drink more and are more likely to binge drink than women, <a href=\"https:\/\/physiology.tamu.edu\/faculty\/michael-c-golding\/\">Dr. Michael Golding<\/a>, an associate professor in the School of Veterinary Medicine &amp; Biomedical Sciences\u2019 Department of Veterinary Physiology &amp; Pharmacology, and his team set out to challenge the existing dogma, using a mouse model to examine what happens when the mother, father, and both parents consume alcohol.<\/p>\n\n\n\n<p>In a <a href=\"https:\/\/doi.org\/10.1172\/JCI167624\" target=\"_blank\" rel=\"noreferrer noopener\">new article<\/a> published in the Journal of Clinical Investigation, Golding and his team found that male alcohol consumption before conception caused FAS brain and facial growth defects.<\/p>\n\n\n\n<p>\u201cWe found that male exposures actually drive certain craniofacial differences much stronger than maternal exposures do, so this programming effect that&#8217;s coming through sperm has a profound effect on the organization of the face and the growth and proportion of different facial features,\u201d Golding said. \u201cWhen it was the dad drinking, we saw a profound shift in the organization of the face.\u201d<\/p>\n\n\n\n<p>According to the <a href=\"https:\/\/www.cdc.gov\/ncbddd\/fasd\/alcohol-use.html\" target=\"_blank\" rel=\"noreferrer noopener\">Centers for Disease Control and Prevention<\/a> (CDC) and the <a href=\"https:\/\/www.niaaa.nih.gov\/publications\/brochures-and-fact-sheets\/fetal-alcohol-exposure\" target=\"_blank\" rel=\"noreferrer noopener\">National Institutes of Health<\/a> (NIH), FAS is a fetal disorder caused by maternal alcohol consumption during pregnancy.<\/p>\n\n\n\n<p>FAS is hard to diagnose, but when doing so, doctors currently look for abnormal facial features; lower-than-average weight, height, or both; central nervous system problems such as a small head size, problems with attention and hyperactivity, or poor coordination; and verification of maternal alcohol use during pregnancy.&nbsp;<\/p>\n\n\n\n<p>\u201cWhen doctors suspect a child has FAS, they sit down with the mother to confirm the diagnosis by discussing her drinking habits during pregnancy,\u201d Golding shared. \u201cIt\u2019s not uncommon for the mother to deny consuming alcohol while pregnant. When they do, there&#8217;s this stigma or this notion that women are lying about their alcohol use.\u201d&nbsp;<\/p>\n\n\n\n<p>Golding said this research, which was funded by a Medical Research Grant from the W.M. Keck Foundation and the NIH National Institute on Alcohol Abuse and Alcoholism, reveals a potential blind spot in the current diagnostic criteria for FAS, the most severe form of Fetal Alcohol Spectrum Disorder (FASD), which requires documentation of maternal alcohol use during pregnancy.<\/p>\n\n\n\n<p>\u201cOur research proves there\u2019s a plausible alternative explanation \u2014 the father\u2019s contribution, which has never been examined before,\u201d he said. \u201cIn this study, we call into question the dismissal of the mother\u2019s denial and really examine the capacity of male alcohol use to induce FAS growth defects.\u201d<\/p>\n\n\n\n<p>Golding explained that findings from his holistic approach that examines both parents\u2019 contributions to FAS reveal the need for two critical changes.&nbsp;<\/p>\n\n\n\n<p>\u201cFirst is the recognition of the importance of male health in pregnancy outcomes and fetal health,\u201d he said. &nbsp;<\/p>\n\n\n\n<p>Golding pointed out that paternal health before conception is a novel consideration in terms of pregnancy outcomes and fetal health; as a result, raising awareness of the role a father&#8217;s health plays in his offspring&#8217;s health is just as important as awareness of the mother&#8217;s contributions from preconception and through gestation.&nbsp;<\/p>\n\n\n\n<p>\u201cResearch examining fetal health is overwhelmingly focused on maternal health,\u201d he said. \u201cI&#8217;m not saying that this is not appropriate; I&#8217;m just saying it&#8217;s not the complete picture and we need some balance.\u201d<\/p>\n\n\n\n<p>\u201cThe second,\u201d he said, \u201cis the fact that both parents are responsible for preventing alcohol-related birth defects.\u201d<\/p>\n\n\n\n<p>FAS has significant, life-changing consequences for children. Because their study identified FAS-related craniofacial differences in offspring born to fathers who regularly consumed alcohol to the legal limit, Golding pointed out that both parents should commit to limiting or omitting their alcohol consumption before trying to become pregnant.<\/p>\n\n\n\n<p>Ultimately, Golding emphasizes that the first step in this process is expanding messaging outreach about the reproductive dangers of alcohol use to both parents.<\/p>\n\n\n\n<p>\u201cChange the alcohol warning label to remove the maternal emphasis and put it on both parents to say, \u2018The decision to consume this beverage can have significant, life-changing consequences to a future child,\u2019\u201d he said. \u201cRight now, the warning label only conveys part of the story. We must get that message out into the world as quickly as possible.\u201d<\/p>\n\n\n\n<p class=\"has-text-align-center\">###<\/p>\n\n\n\n<p><em>For more information about the Texas A&amp;M College of Veterinary Medicine &amp; Biomedical Sciences, please visit our website at\u00a0<\/em><a href=\"https:\/\/vetmed.tamu.edu\/\"><em>vetmed.tamu.edu<\/em><\/a><em>\u00a0or join us on\u00a0<\/em><a href=\"https:\/\/www.facebook.com\/tamuvetmed\"><em>Facebook<\/em><\/a><em>,\u00a0<\/em><a href=\"https:\/\/www.instagram.com\/tamuvetmed\/\"><em>Instagram<\/em><\/a><em>, and\u00a0<\/em><a href=\"https:\/\/twitter.com\/tamuvetmed\"><em>X<\/em><\/a><em>.<\/em><\/p>\n\n\n\n<p><strong><em>Contact Information:<\/em><\/strong><em>&nbsp;Jennifer Gauntt, Director of VMBS Communications, Texas A&amp;M College of Veterinary Medicine &amp; Biomedical Sciences,&nbsp;<\/em><a href=\"mailto:jgauntt@cvm.tamu.edu\"><em>jgauntt@cvm.tamu.edu,<\/em><\/a><em>&nbsp;<a href=\"tel:979-862-4216\">979-862-4216<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fetal alcohol syndrome-related craniofacial differences could be seen in offspring born to fathers who regularly consumed alcohol to the legal limit. According to the U.S. Surgeon General, women should not drink alcoholic beverages during pregnancy because of the risk of birth defects in their unborn child. However, research at Texas A&amp;M University now demonstrates that [&hellip;]<\/p>\n","protected":false},"author":269,"featured_media":19592,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"2069,2070,2071,2073,2074,2075","_relevanssi_noindex_reason":"","_uag_custom_page_level_css":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[13038,4,8],"class_list":["post-19590","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-releases","tag-michael-golding","tag-research","tag-vtpp"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Father&#039;s Alcohol Consumption Linked To Defects In Offspring<\/title>\n<meta name=\"description\" content=\"Fetal alcohol syndrome-related craniofacial differences could be seen in offspring born to fathers with regular alcohol comsumption.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vetmed.tamu.edu\/news\/press-releases\/fathers-alcohol-linked-to-offspring-defects\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Father&#039;s Alcohol Consumption Before Conception Linked To Brain And Facial Defects In Offspring\" \/>\n<meta property=\"og:description\" content=\"Fetal alcohol syndrome-related craniofacial differences could be seen in offspring born to fathers who regularly consumed alcohol to the legal limit. 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alcohol syndrome-related craniofacial differences could be seen in offspring born to fathers who regularly consumed alcohol to the legal limit. According to the U.S. Surgeon General, women should not drink alcoholic beverages during pregnancy because of the risk of birth defects in their unborn child. 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