{"id":24300,"date":"2025-11-13T09:01:50","date_gmt":"2025-11-13T15:01:50","guid":{"rendered":"https:\/\/vetmed.tamu.edu\/news\/?p=24300"},"modified":"2025-12-25T22:42:47","modified_gmt":"2025-12-26T04:42:47","slug":"equine-sepsis-hemoperfusion","status":"publish","type":"post","link":"https:\/\/vetmed.tamu.edu\/news\/press-releases\/equine-sepsis-hemoperfusion\/","title":{"rendered":"Texas A&M Clinical Trial Transforming Care For Equine Sepsis Patients"},"content":{"rendered":"
\n
\"Dr.
Dr. Kallie Hobbs with April, the first horse treated with hemoperfusion<\/figcaption><\/figure>\n<\/div>\n\n\n

Sepsis, a severe reaction to a bacterial infection, is among the most common and life-threatening conditions in horses. Foals are especially vulnerable because their immune systems are still developing; they can be exposed to bacteria either through their mother before birth or from the environment shortly after being born.<\/p>\n\n\n\n

When a foal or adult horse is septic, its body\u2019s immune system releases inflammatory signals called cytokines to help regulate the immune response. However, this unregulated release often causes a dangerous overproduction in cytokines, called a cytokine storm, that overwhelms the immune system and leaves it unable to fight off the very infection it was trying to stop \u2014 often resulting in death of the horse.<\/p>\n\n\n\n

That\u2019s why Dr. Kallie Hobbs<\/a>, an assistant professor of equine and food animal internal medicine at the Texas A&M College of Veterinary Medicine & Biomedical Sciences, is exploring hemoperfusion, a method of cleaning the blood to help restore the body\u2019s natural ability to fight off infection.<\/p>\n\n\n\n

\u201cThis process involves a catheter that draws blood from the horse, which then passes through a hemoperfusion column filled with adsorbent material,\u201d Hobbs said. \u201cAfter being filtered, the blood is returned to the animal without excess inflammatory signals.\u201d<\/p>\n\n\n\n

This technology \u2014 originally developed to treat severe COVID-19 cases in humans \u2014 is still new in the veterinary world, and now, Texas A&M is one of the only programs in the country offering this treatment for large animals.<\/p>\n\n\n\n

\u201cThis is considered part of standard care in humans,\u201d Hobbs said. \u201cAnd now it\u2019s starting to become part of cutting-edge care in veterinary medicine, too.\u201d<\/p>\n\n\n\n

As part of the Texas A&M Large Animal Teaching Hospital\u2019s<\/a> clinical trial, the hemoperfusion treatment itself is currently free, thanks to industry support and research funding. Owners are only responsible for the horse\u2019s hospital stay, diagnostics, and supportive care.<\/p>\n\n\n

\n
\"Dr.
Hobbs with Texas A&M\u2019s hemoperfusion equipment<\/figcaption><\/figure>\n<\/div>\n\n\n

\u201cIn return, we\u2019re able to document those animals in case reports and track their progress,\u201d Hobbs said. \u201cFor some owners, it might be the only chance to save a horse that\u2019s not responding to anything else. I\u2019ve filtered blood in several horses with sepsis and have noted a rapid improvement in their clinical signs.\u201d<\/p>\n\n\n\n

While sepsis is the trial\u2019s central focus, Hobbs and her team have started applying hemoperfusion to other emergencies, like toxicity cases involving rat bait ingestion or snake envenomation \u2014 instances where dangerous substances can be physically removed from the bloodstream.<\/p>\n\n\n\n

Behind the scenes, the success of the trial is powered by cross-hospital collaboration. Hobbs has partnered with Drs. Igor Yankin<\/a> and Lance Wheeler<\/a>, at Texas A&M\u2019s Small Animal Teaching Hospital<\/a>, where hemoperfusion has recently become a new treatment option for dogs in the Emergency and Critical Care Services.<\/p>\n\n\n\n

\u201cIf people see that we saved a dog\u2019s life with this, they\u2019re more willing to try it for their horse,\u201d Hobbs said. \u201cIt helps validate the whole process.\u201d<\/p>\n\n\n\n

Looking ahead, Hobbs hopes to develop protocols to better refine treatment of sepsis and determine which types of infections respond best to hemoperfusion.<\/p>\n\n\n\n

\u201cMy hope is that hemoperfusion becomes a management strategy we can use early, instead of waiting until everything else has failed,\u201d she said.<\/p>\n\n\n\n

###<\/p>\n\n\n\n

For more information about the Texas A&M College of Veterinary Medicine & Biomedical Sciences, please visit our website at\u00a0<\/em>vetmed.tamu.edu<\/em><\/a>\u00a0or join us on\u00a0<\/em>Facebook<\/em><\/a>,\u00a0<\/em>Instagram<\/em><\/a>, and\u00a0<\/em>X<\/em><\/a>.<\/em><\/p>\n\n\n\n

Contact Information:<\/em><\/strong> Jennifer Gauntt, Director of VMBS Communications, Texas A&M College of Veterinary Medicine & Biomedical Sciences, <\/em>jgauntt@cvm.tamu.edu,<\/em><\/a> 979-862-4216<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Sepsis, a severe reaction to a bacterial infection, is among the most common and life-threatening conditions in horses. Foals are especially vulnerable because their immune systems are still developing; they can be exposed to bacteria either through their mother before birth or from the environment shortly after being born. When a foal or adult horse […]<\/p>\n","protected":false},"author":269,"featured_media":24302,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"2069,2070,2071,2073,2074,2075","_relevanssi_noindex_reason":"","_uag_custom_page_level_css":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[188,2],"tags":[13827,13902,27,13914,4,7,32],"class_list":["post-24300","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-homepage","category-press-releases","tag-clinical-trials","tag-kallie-hobbs","tag-lath","tag-legends-horses","tag-research","tag-vlcs","tag-vmth"],"acf":[],"yoast_head":"\nHemoperfusion 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a severe reaction to a bacterial infection, is among the most common and life-threatening conditions in horses. Foals are especially vulnerable because their immune systems are still developing; they can be exposed to bacteria either through their mother before birth or from the environment shortly after being born. When a foal or adult horse…","_links":{"self":[{"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/posts\/24300","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/users\/269"}],"replies":[{"embeddable":true,"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/comments?post=24300"}],"version-history":[{"count":0,"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/posts\/24300\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/media\/24302"}],"wp:attachment":[{"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/media?parent=24300"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/categories?post=24300"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vetmed.tamu.edu\/news\/wp-json\/wp\/v2\/tags?post=24300"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}