Paige Adams
Instructional Associate Professor Department of Veterinary PathobiologyTAMU Mailstop: 4467
Research and Scholarly Interests
My scholarly interests span emerging viral diseases, host immune responses, and vaccine development within a One Health framework. I also study educational approaches that strengthen veterinary, public health, and animal health workforce preparation.
Education
- B.S., Texas A&M University, 1990
- D.V.M., Texas A&M University, 1993
- Ph.D., Cornell University, 2004
Credentials
- Texas Board of Veterinary Medical Examiners, starting 1993
- Emerging and zoonotic infectious diseases
- Viral pathogenesis, immunology, and host responses
- Vaccine, biologics, and therapeutic development
- One Health and public health
- Veterinary education, animal health regulatory science, and workforce development
My background combines advanced clinical training in large-animal medicine and surgery with research expertise in immunology, emerging viral diseases, vaccine development, and One Health. My previous research examined the pathogenesis, immune responses, evolution, and transmission of arboviruses—including Venezuelan and eastern equine encephalitis and chikungunya viruses—and contributed to the development and evaluation of vaccines, animal models, and antiviral strategies. These experiences align closely with the Texas A&M College of Veterinary Medicine and Biomedical Sciences’ strengths in veterinary education, infectious disease research, translational science, and the advancement of animal, human, and public health.
VTPB 425 – Biomedical Microbiology
Peer Reviewed Publications (37 total, h-index=25 with 2925 citations)
King C, Adams AP. The One Health Blind Spot in U.S. Influenza Surveillance. Am J Public Health 2026;116:1220-1228. https://doi.org/10.2105/AJPH.2026.308445
Brady A, Haas S, Pike M, Ghrist M, Adams AP, Mulcahy ER. A crosswalk analysis of one health curriculum. Pedagogy Health Promot 2026. Under review
Adams AP, Stuteville R, Wolfe BA. Managing and motivating academic advisory boards in animal health for high performance. Front Educ 2025;10: Article 1508824. https://doi.org/10.3389/feduc.2025.1508824
Jojola-Mount V, Haas S, Brady A, Adams AP, Mulcahy ER. Interprofessional skills development in public health: Perceptions, knowledge gaps, and learning opportunities. Int J Epidemiol Public Health Res 2023;3(2).
Shridhar PB, Amachawadi RG, Atobatele M, Shi X, Adams AP, Phebus RK, Nagaraja TG. Draft genome sequences of Salmonella enterica subsp. diarizonae serotype IIIb_61:I,v:1,5,(7) strains isolated from wheat grains. Microbiol Resour Announc. 2021;10(20):e00035-21.
Forrester NL, Auguste AJ, Dugan VG, Wortheim JO, Adams AP, Chen R, Gorchakov R, Leal G, Pandya J, Halpin RA, Stockwell TB, Wentworth DE, Smith M, Kosakovsky SL, Weaver SC. Evolution and spread of Venezuelan equine encephalitis complex alphaviruses in the Americas. PLoS Negl Trop Dis 2017;11(8):e0005693.
Seymour RL*, Adams AP*, Leal G, Alcorn MDH, Weaver SC. A rodent model of chikungunya virus infection in RAG1-/- mice, with features of persistence, for vaccine safety evaluation. PLoS Negl Trop Dis 2015;9(6):e0003800.
Weise WJ, Hermance ME, Forrester NL, Adams AP, Langsjoen R, Gorchakov R, Wang E, Alcorn MDH, Tsetsarkin K, Weaver SC. A novel live-attenuated vaccine candidate for Mayaro fever. PLoS Negl Trop Dis 2014;8(8):e2969.
Roy CJ, Adams AP, Wang E, Plante K, Gorchakov R, Seymour RL, Vinet-Oliphant H, Weaver SC. Chikungunya vaccine candidate is highly attenuated and protects nonhuman primates against Disease following a single dose. J Infect Dis 2014;209:1891-1899.
Roy CJ*, Adams AP*, Wang E, Leal G, Seymour RL, Sivasubramani S, Mega W, Frolov I, Killeen SZ, Didier PJ, Weaver SC. A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus. Vaccine 2013;31:1464-1470.
Kalvatchev N, Christova I, Weaver SC, Adams AP. Review and case report of a Bulgarian patient with Dobrava virus infection and associated hemorrhagic fever with renal syndrome. Biotechnol & Biotechnol Eq 2013;27:3465-3469.
Adams AP, Siirin M, Travassos da Rosa APA, Nunes MR, Xiao S-Y, Tesh RB. Pathogenesis of Modoc virus (Flaviviridae; Flavivirus) in persistently infected hamsters. Am J Trop Med Hyg 2013;88:455-460.
Adams AP, Navarro-Lopez R, Ramirez-Aguilar F, Lopez-Gonzalez I, Leal G, Flores-Mayorga JM, Travassos Da Rosa A, Saxton-Shaw KD, Singh AJ, Borland EM, Powers AM, Tesh RB, Weaver SC, Estrada-Franco JG. Venezuelan equine encephalitis virus activity in the Gulf Coast region of Mexico, 2003-2010. PLoS Negl Trop Dis 2012;6:e1875.
Gorchakov R, Wang E, Leal G, Forrester NL, Plante K, Rossi SL, Partidos CD, Adams AP, Seymour RL, Weger J, Borland EM, Sherman MB, Powers AM, Osorio JE, Weaver SC. Attenuation of chikungunya vaccine strain 181/clone 25 is determined by 2 amino acid substitutions in the E2 envelope glycoprotein. J Virol 2012;86:6084-6096.
Kenney JL, Adams AP, Gorchakov R, Leal G, Weaver SC. Adaptation of arboviruses to mosquitoes: Determinants of infection of enzootic Venezuelan equine encephalitis virus in Culex (Melanoconion) taeniopus. PLoS Negl Trop Dis 2012;6:e1606.
Zasloff M, Adams AP, Beckerman B, Campbell A, Han Z, Meza I, Julander J, Mishra A, Qu W, Taylor JM, Weaver SC, Wong, GC. Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential. PNAS 2011;108:15978-15983.
Forrester NL, Guerbois M, Adams AP, Liang X, Weaver SC. Analysis of intra-host variation in Venezuelan equine encephalitis virus reveals repeated deletions in the 6-kilodalton protein gene. J Virol 2011;85:8709-8717.
de Mestre AM, Hanlon D, Adams AP, Runcan E, Leadbeater JC, Erb HN, Costa CC, Miller D, Allen WR, Antczak DF. Functions of ectopically transplanted invasive horse trophoblast. Reproduction 2011;141:849-856.
Auguste AJ, Adams AP, Arrigo NC, Martinez R, Travassos Da Rosa APA, Adesiyun AA, Chadee DD, Tesh RB, Carrington CVF, Weaver SC. Isolation and characterization of sylvatic mosquito-borne viruses in Trinidad: Enzootic transmission and a new potential vector of Mucambo virus. Am J Trop Med Hyg 2010;83:1262-1265.
Arrigo NC, Adams AP, Watts DM, Newman PC, Weaver SC. Cotton rats (Sigmodon hispidus) and house sparrows (Passer domesticus) as amplification hosts of North and South American strains of eastern equine encephalitis virus. EID 2010;16:1373-1380.
Volk SM, Chen R, Tsetsarkin KA, Adams AP, Garcia TI, Sall AA, Nasar F, Schuh AJ, Holmes EC, Higgs S, Brault AC, Maharaj PD, Weaver SC. Genome scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and varying evolutionary rates. J Virol 2010;84:6497-6504.
Kenney JL, Adams AP, Weaver SC. Transmission potential of two chimeric western equine encephalitis vaccine candidates in Culex tarsalis. Am J Trop Med Hyg 2010;82:354-359.
Arrigo NC, Adams AP, Weaver SC. Evolutionary patterns of eastern equine encephalitis virus in North versus South America suggest ecological differences and taxonomic revision. J Virol 2010;84:1014-1025.
Aguilar PV, Adams AP, Vargas J, Mannock S, Diaz A, Liang X, Roca Y, Weaver SC, Kochel TJ. Endemic circulation of Venezuelan equine encephalitis virus in Bolivia, Ecuador and Peru: Identification of a new subtype ID genetic lineage. PLoS Negl Trop Dis 2009;3:e514.
Auguste AJ, Volk SM, Arrigo NC, Martinez R, Ramkissoon V, Adams AP, Thompson NN, Adesiyun AA, Chadee DD, Foster JE, Travassos Da Rosa AP, Tesh RB, Weaver SC, Carrington CVF. Isolation and phylogenetic analysis of Mucambo virus (Venezuelan equine encephalitis virus subtype IIIA) in Trinidad. Virology 2009;392:123-130.
Atasheva S*, Wang E*, Adams AP*, Plante KS, Ni S, Taylor K, Miller ME, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates provide complete protection in mice after intranasal challenge with western equine encephalitis virus. Vaccine 2009;27:4309-4319.
Adams AP, Aronson JF, Tardif SD, Patterson JL, Brasky KM, Geiger R, de la Garza M, Carrion R, Jr., Weaver SC. Common marmosets (Callithrix jacchus) as a nonhuman primate model to assess the virulence of eastern equine encephalitis virus strains. J Virol 2008;82:9035-9042.
Wang E, Volkova E, Adams AP, Forrester N, Xiao S-Y, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates for chikungunya. Vaccine 2008;26:5030-5039.
Aguilar PV*, Adams AP*, Wang E, Carrara A-S, Anishchenko M, Frolov I, Weaver SC. Structural and nonstructural genes of eastern equine encephalitis virus are determinants of interferon sensitivity and mouse neurovirulence. J Virol 2008;82:4920-4930.
Smith DR, Adams AP, Kenney JL, Wang E, Weaver SC. Venezuelan equine encephalitis virus in the mosquito vector Aedes taeniorhynchus: infection initiated by a small number of susceptible epithelial cells and a population bottleneck. Virology 2008;372:176-186.
Wang E, Petrakova O, Adams AP, Aguilar PV, Kang W, Paessler S, Frolov I, Weaver SC. Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice. Vaccine 2007;25:7573-7581.
Adams AP*, Oriol RE*, Campbell RE, Oppenheim YC, Antczak DF. The effect of skin allografting on the equine endometrial cup reaction. Theriogenology 2007;68:237-247.
Adams AP, Antczak DF. Ectopic transplantation of equine invasive trophoblast. Biol Reprod 2001;64:753-763.
Adams AP, Santschi EM, Mellencamp MA. Antibacterial properties of a silver chloride-coated nylon wound dressing. Vet Surg 1999;28:219-225.
Boussauw B, Santschi EM, Wilderjans H, Troedsson MH, Adams AP. Uterine drainage under general anaesthesia before ovariohysterectomy in two mares. Vet Rec 1998;142:582-583.
Adams AP, Collatos C, Fuentealba C, Illanes O, Blanchard R. Neuroaxonal dystrophy in a two year old Quarter Horse filly. Can Vet J 1996;37:43-44.
Adams AP, Honnas CM, Ford TS, Watkins JP. Arthrodesis of a subluxated proximal interphalangeal joint in a horse. Equine Pract 1995;17(3):26-31.
*Authors contributed equally to this work.