Biomedical Genomics

Program Overview

Biomedical Genomics

The program in biomedical genomics strives for excellence in newly evolving areas of animal genomics and proteomics. The aim is to:

  • improve understanding of molecular mechanisms controlling or affecting disease manifestation, disease susceptibility and resistance, diagnostics, prevention and treatment;
  • improve animal health, reproduction and welfare;
  • train students in classical and cutting edge genomics approaches;
  • provide student and postdoc access to a highly trained interdisciplinary team in animal genomics.

Research emphasis areas

  • Mammalian genomics (all participants)
  • Comparative genomics (all participants)
  • Population genomics (Cai, Cothran, Derr, Janecka, Murphy, Samollow, Seabury)
  • Conservation genomics (Cothran, Derr, Janecka, Murphy)
  • Phylogenomics and genome evolution (Cai, Janecka, Murphy, Samollow,)
  • Immunogenomics (Criscitiello, Skow, Seabury, Womack)
  • Functional genomics (Chowdhary, Raudsepp, Murphy, Samollow, Riggs)
  • Mammalian disease genomics (Chowdhary, Cothran, Derr, Janecka, Seabury, Skow, Womack)
  • Genomics of sex and reproduction (Chowdhary, Murphy, Raudsepp)
  • Computational genomics (Cai, Murphy, Seabury)
  • Epigenomics (Dindot, Samollow)
  • Disease proteomics (Chowdhary)

Introduction

Biomedical Genomics

Genomics is a key and rapidly evolving research discipline that continuously elucidates new dimensions within the dynamic structure of modern biomedicine. The animal genomics research community has witnessed an astonishing expansion and diversification throughout the past decade. Completion of the human and mouse genome sequences sparked enormous interest in the annotation of these genomes through a series of detailed comparative analyses. As a result, genome sequences are now available for nearly all major mammalian companion and livestock species, including cattle, pig, dog, horse, cat, alpaca and chicken, as well as biomedical models such as the rat, rabbit, opossum, shark and Xenopus genomes. Rapid methodological and computational advancements afforded by genome sequence data are providing the means for new areas of research that could barely be imagined just a few years ago. The study and analysis of animal genomes continuously provides new technologies to better understand phenotypes of biomedical and economic importance in these species, while at the same time informing human biology.

Faculty

MACRO PLACEHOLDER