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Ernest Gus Cothran, Jr.

Clinical Professor

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Phone: (979) 845-0229

Mailstop: 4458

Department: VIBS

Photo of Cothran, Jr., Ernest  Gus

Web Presence

Education

  • Ph.D. Genetics, University of Oklahoma 1982
  • M.S. Zoology, North Texas State University 1975
  • B.S. Zoology, North Texas State University 1973

Research

  • Biomedical Genomics

Interdisciplinary Activities

  • Genetics

Scholarly Interests

heredity basis of equine congenital defects and economically significant traits in domestic animals (mainly the horse); interrelationships of inbreeding, genetic polymorphism, and reproductive performance in horses; population genetics of feral horses; comparative aspects of genetics variation in horses under human selection and under natural selection; genetic aspects of captivity; genetics of domestication. Management of genetic polymorphism in small populations and conservation of rare breeds; genetic relationship among domestic horse breeds; changes in gene regulation based upon environmental factors; gene mapping of the horse.

Publications

The legend of the Canadian Horse: Genetic diversity and breed origin.
Khanshour A., Juras R., Blackburn R., Cothran G.
Journal of Heredity. 2015
Copy number variation in the horse genome.
Ghosh S, Qu Z, Das PJ, Fang E, Juras R, Cothran EG, McDonell S, Kenney DG, Lear TL, Adelson DL, Chowdhary BP, Raudsepp T
PLoS Genet. 2014 10(10):.
Worldwide frequency distribution of the 'Gait keeper' mutation in the DMRT3 gene.
Promerová M, Andersson LS, Juras R, Penedo MC, Reissmann M, Tozaki T, Bellone R, Dunner S, Hořín P, Imsland F, Imsland P, Mikko S, Modrý D, Roed KH, Schwochow D, Vega-Pla JL, Mehrabani-Yeganeh H, Yousefi-Mashouf N, G Cothran E, Lindgren G, Andersson L
Anim Genet. 2014 45(2):274-82.
Equine multiple congenital ocular anomalies and silver coat colour result from the pleiotropic effects of mutant PMEL.
Andersson LS, Wilbe M, Viluma A, Cothran G, Ekesten B, Ewart S, Lindgren G
PLoS One. 2013 8(9):.
Microsatellite analysis of genetic diversity and population structure of Arabian horse populations.
Khanshour A, Conant E, Juras R, Cothran EG
J Hered. 2013 104(3):386-98.
Genetic diversity in the modern horse illustrated from genome-wide SNP data.
Petersen JL, Mickelson JR, Cothran EG, Andersson LS, Axelsson J, Bailey E, Bannasch D, Binns MM, Borges AS, Brama P, da Câmara Machado A, Distl O, Felicetti M, Fox-Clipsham L, Graves KT, Guérin G, Haase B, Hasegawa T, Hemmann K, Hill EW, Leeb T, Lindgren G, Lohi H, Lopes MS, McGivney BA, Mikko S, Orr N, Penedo MC, Piercy RJ, Raekallio M, Rieder S, Røed KH, Silvestrelli M, Swinburne J, Tozaki T, Vaudin M, M Wade C, McCue ME
PLoS One. 2013 8(1):.
Genome-wide analysis reveals selection for important traits in domestic horse breeds.
Petersen JL, Mickelson JR, Rendahl AK, Valberg SJ, Andersson LS, Axelsson J, Bailey E, Bannasch D, Binns MM, Borges AS, Brama P, da Câmara Machado A, Capomaccio S, Cappelli K, Cothran EG, Distl O, Fox-Clipsham L, Graves KT, Guérin G, Haase B, Hasegawa T, Hemmann K, Hill EW, Leeb T, Lindgren G, Lohi H, Lopes MS, McGivney BA, Mikko S, Orr N, Penedo MC, Piercy RJ, Raekallio M, Rieder S, Røed KH, Swinburne J, Tozaki T, Vaudin M, Wade CM, McCue ME
PLoS Genet. 2013 9(1):.
Identification of copy number variants in horses.
Doan R, Cohen N, Harrington J, Veazey K, Juras R, Cothran G, McCue ME, Skow L, Dindot SV
Genome Res. 2012 22(5):899-907.
Incidence of the mask phenotype M264V mutation in Labrador Retrievers.
Conant EK, Juras R, Cothran EG
Res Vet Sci. 2011 91(3):.
Genetic analysis of the Venezuelan Criollo horse.
Cothran EG, Canelon JL, Luis C, Conant E, Juras R
Genet Mol Res. 2011 10(4):2394-403.
Targeted analysis of four breeds narrows equine Multiple Congenital Ocular Anomalies locus to 208 kilobases.
Andersson LS, Lyberg K, Cothran G, Ramsey DT, Juras R, Mikko S, Ekesten B, Ewart S, Lindgren G
Mamm Genome. 2011 22(5-6):353-60.
European domestic horses originated in two holocene refugia.
Warmuth V, Eriksson A, Bower MA, Cañon J, Cothran G, Distl O, Glowatzki-Mullis ML, Hunt H, Luís C, do Mar Oom M, Yupanqui IT, Ząbek T, Manica A
PLoS One. 2011 6(3):.
Genetic variability in the Skyros pony and its relationship with other Greek and foreign horse breeds.
Bömcke E, Gengler N, Cothran EG
Genet Mol Biol. 2011 34(1):68-76.
Equine Multiple Congenital Ocular Anomalies maps to a 4.9 megabase interval on horse chromosome 6.
Andersson LS, Juras R, Ramsey DT, Eason-Butler J, Ewart S, Cothran G, Lindgren G
BMC Genet. 2008 9(9):88.
A missense mutation in PMEL17 is associated with the Silver coat color in the horse.
Brunberg E, Andersson L, Cothran G, Sandberg K, Mikko S, Lindgren G
BMC Genet. 2006 7(7):46.
Iberian origins of New World horse breeds.
Luís C, Bastos-Silveira C, Cothran EG, Oom Mdo M
J Hered. 2006 97(2):107-13.
Limited number of patrilines in horse domestication.
Lindgren G, Backström N, Swinburne J, Hellborg L, Einarsson A, Sandberg K, Cothran G, Vilà C, Binns M, Ellegren H
Nat Genet. 2004 36(4):335-6.


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