An opportunity exists for the right new student to work towards
a PhD studying MHC (okay, MH) population genetics using a unique
dataset containing whole genome sequencing data from the Atlantic
herring (Clupea harengus) of hundreds of fish from tens of
locations (see eLife: https://elifesciences.org/articles/12081).
The student would be mentored by Leif Andersson, and also work
closely with Brian Davis and myself here at Texas A&M.
Schools of Atlantic herring can contain billions of
individuals, and this is one of the most numerous vertebrates on
Earth. We have a singular opportunity to study immunogenetics with
a massive collection of genomic data from fish of differing
location, migration patterns, reproductive timing, and salinity
adaptation. A unique feature of this species is the lack of genetic
differentiation at selectively neutral loci which makes it
particularly informative to study the consequences of natural
selection. The student will learn how to work with NGS data. A
particular focus will be to reveal the genetic organization of MHC
genes, their genetic diversity and to which extent MHC genes
contribute to adaptation.
If you are interested, please contact Dr. Mike Criscitiello for