Pancreatic Lipase Immunoreactivity (PLI)

Please follow this link for more information on canine and feline pancreatitis.

Sample

0.5 ml fasting (12-18 hours) non-hemolyzed serum

Turnaround: 2-3 business days after receipt of samples.

Reference Intervals

Feline (Spec fPL™) 0 – 4.4 µg/L
Canine (Spec cPL™) 0 – 200 µg/L

Interpretation

Cats

≤4.4 µg/L Serum Spec fPL concentration is within the reference interval. It is unlikely that the cat has pancreatitis. Investigate for other diseases that could cause the observed clinical signs.
4.5 – 8.7 µg/L Questionable range. The cat may have pancreatitis and Spec fPL should be reevaluated in 2-3 weeks if clinical signs persist. Also, the patient should be evaluated for other differential diagnoses.
≥8.8 µg/L Consistent with pancreatitis. Also, consider investigating for risk factors and concurrent diseases (e.g., IBD, cholangitis, diabetes mellitus).

Dogs

≤ 200 µg/L Result within the reference interval.
201 to 399 µg/L Questionable range. This patient may have pancreatitis and serum cPLI should be reevaluated in 2-3 weeks. Also, the patient should be evaluated for other differential diagnoses.
≥ 400 µg/L Consistent with pancreatitis. Treatment can be monitored by repeated serum cPLI analysis.