Pancreatic Lipase Immunoreactivity (PLI)

Please follow this link for more information on canine and feline pancreatitis.

Sample

0.5 ml fasting (12-18 hours) non-hemolyzed serum

Turnaround: 1-2 business days after receipt of samples.

Reference Intervals

Feline (Spec fPL™) 0 - 3.5 µg/L
Canine (Spec cPL™) 0 - 200 µg/L

Interpretation

Cats

≤3.5 µg/L Serum Spec fPL concentration is in the reference interval. It is unlikely that the cat has pancreatitis. Investigate for other diseases that could cause observed clinical signs.
3.6 - 5.3 µg/L Serum Spec fPL concentration is increased. The cat may have pancreatitis and Spec fPL should be reevaluated in two weeks if clinical signs persist. Investigate for other diseases that could cause observed clinical signs.
≥5.4 µg/L Serum Spec fPL concentration is consistent with pancreatitis. The cat most likely has pancreatitis. Consider investigating for risk factors and concurrent diseases (e.g., IBD, hepatitis, Diabetes mellitus). Periodic monitoring of Spec fPL may help assess response to therapy.

Dogs

0 to 200 µg/L Result within the reference interval.
201 to 399 µg/L Questionable range. This patient may have pancreatitis and serum cPLI should be reevaluated in 2-3 weeks. Also, the patient should be evaluated for other differential diagnoses.
> 400 µg/L Consistent with pancreatitis. Treatment can be monitored by repeated serum cPLI analysis.

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