E. Cothran, Jr.
Professor Emeritus & Consultant, Animal Genetics Lab Department of Veterinary Integrative Biosciences
TAMU Mailstop: 4458
Research and Scholarly Interests
heredity basis of equine congenital defects and economically significant traits in domestic animals (mainly the horse); interrelationships of inbreeding, genetic polymorphism, and reproductive performance in horses; population genetics of feral horses; comparative aspects of genetics variation in horses under human selection and under natural selection; genetic aspects of captivity; genetics of domestication. Management of genetic polymorphism in small populations and conservation of rare breeds; genetic relationship among domestic horse breeds; changes in gene regulation based upon environmental factors; gene mapping of the horse.
EDUCATION
- B.S., North Texas State University, 1973
- M.S. , North Texas State University, 1975
- Ph.D., University of Oklahoma, 1982
- Genomics
- Genetics
- Luís C, Bastos-Silveira C, Cothran EG, Oom Mdo M (2006). Iberian origins of New World horse breeds. J HERED. 2, 107-13
- Andersson LS, Juras R, Ramsey DT, Eason-Butler J, Ewart S, Cothran G, Lindgren G (2008). Equine Multiple Congenital Ocular Anomalies maps to a 4.9 megabase interval on horse chromosome 6. BMC GENET. 9, 88
- Promerová M, Andersson LS, Juras R, Penedo MC, Reissmann M, Tozaki T, Bellone R, Dunner S, Hořín P, Imsland F, Imsland P, Mikko S, Modrý D, Roed KH, Schwochow D, Vega-Pla JL, Mehrabani-Yeganeh H, Yousefi-Mashouf N, G Cothran E, Lindgren G, Andersson L (2014). Worldwide frequency distribution of the 'Gait keeper' mutation in the DMRT3 gene. ANIM GENET. 2, 274-82
- Luís C, Cothran EG, Oom Mdo M (2007). Inbreeding and genetic structure in the endangered Sorraia horse breed: implications for its conservation and management. J HERED. 3, 232-7
- Brunberg E, Andersson L, Cothran G, Sandberg K, Mikko S, Lindgren G (2006). A missense mutation in PMEL17 is associated with the Silver coat color in the horse. BMC GENET. 7, 46
- Lindgren G, Backström N, Swinburne J, Hellborg L, Einarsson A, Sandberg K, Cothran G, Vilà C, Binns M, Ellegren H (2004). Limited number of patrilines in horse domestication. NAT GENET. 4, 335-6
- Bömcke E, Gengler N, Cothran EG (2011). Genetic variability in the Skyros pony and its relationship with other Greek and foreign horse breeds. GENET MOL BIOL. 1, 68-76
- Warmuth V, Eriksson A, Bower MA, Cañon J, Cothran G, Distl O, Glowatzki-Mullis ML, Hunt H, Luís C, do Mar Oom M, Yupanqui IT, Ząbek T, Manica A (2011). European domestic horses originated in two holocene refugia. PLOS ONE. 3,
- Andersson LS, Lyberg K, Cothran G, Ramsey DT, Juras R, Mikko S, Ekesten B, Ewart S, Lindgren G (2011). Targeted analysis of four breeds narrows equine Multiple Congenital Ocular Anomalies locus to 208 kilobases. MAMM GENOME. 5-6, 353-60
- Ghosh S, Qu Z, Das PJ, Fang E, Juras R, Cothran EG, McDonell S, Kenney DG, Lear TL, Adelson DL, Chowdhary BP, Raudsepp T (2014). Copy number variation in the horse genome. PLOS GENET. 10,
- Andersson LS, Wilbe M, Viluma A, Cothran G, Ekesten B, Ewart S, Lindgren G (2013). Equine multiple congenital ocular anomalies and silver coat colour result from the pleiotropic effects of mutant PMEL. PLOS ONE. 9,
- Khanshour AM, Cothran EG (2013). Maternal phylogenetic relationships and genetic variation among Arabian horse populations using whole mitochondrial DNA D-loop sequencing. BMC GENET. 14, 83
- Khanshour A, Conant E, Juras R, Cothran EG (2013). Microsatellite analysis of genetic diversity and population structure of Arabian horse populations. J HERED. 3, 386-98
- Petersen JL, Mickelson JR, Cothran EG, Andersson LS, Axelsson J, Bailey E, Bannasch D, Binns MM, Borges AS, Brama P, da Câmara Machado A, Distl O, Felicetti M, Fox-Clipsham L, Graves KT, Guérin G, Haase B, Hasegawa T, Hemmann K, Hill EW, Leeb T, Lindgren G, Lohi H, Lopes MS, McGivney BA, Mikko S, Orr N, Penedo MC, Piercy RJ, Raekallio M, Rieder S, Røed KH, Silvestrelli M, Swinburne J, Tozaki T, Vaudin M, M Wade C, McCue ME (2013). Genetic diversity in the modern horse illustrated from genome-wide SNP data. PLOS ONE. 1,
- Petersen JL, Mickelson JR, Rendahl AK, Valberg SJ, Andersson LS, Axelsson J, Bailey E, Bannasch D, Binns MM, Borges AS, Brama P, da Câmara Machado A, Capomaccio S, Cappelli K, Cothran EG, Distl O, Fox-Clipsham L, Graves KT, Guérin G, Haase B, Hasegawa T, Hemmann K, Hill EW, Leeb T, Lindgren G, Lohi H, Lopes MS, McGivney BA, Mikko S, Orr N, Penedo MC, Piercy RJ, Raekallio M, Rieder S, Røed KH, Swinburne J, Tozaki T, Vaudin M, Wade CM, McCue ME (2013). Genome-wide analysis reveals selection for important traits in domestic horse breeds. PLOS GENET. 1,
- Prystupa JM, Hind P, Cothran EG, Plante Y (2012). Maternal lineages in native Canadian equine populations and their relationship to the Nordic and Mountain and Moorland pony breeds. J HERED. 3, 380-90
- Doan R, Cohen N, Harrington J, Veazey K, Juras R, Cothran G, McCue ME, Skow L, Dindot SV (2012). Identification of copy number variants in horses. GENOME RES. 5, 899-907
- Conant EK, Juras R, Cothran EG (2012). A microsatellite analysis of five Colonial Spanish horse populations of the southeastern United States. ANIM GENET. 1, 53-62
- Cothran EG, Canelon JL, Luis C, Conant E, Juras R (2011). Genetic analysis of the Venezuelan Criollo horse. GENET MOL RES. 4, 2394-403
- Conant EK, Juras R, Cothran EG (2011). Incidence of the mask phenotype M264V mutation in Labrador Retrievers. RES VET SCI. 3,
- Khanshour A., Juras R., Blackburn R., Cothran G. (2015). The legend of the Canadian Horse: Genetic diversity and breed origin. JOURNAL OF HEREDITY.