Texas A&M University 150 Here for Good logo
Celebrating 110 Years of Service & Science at the College of Veterinary Medicine & Biomedical Sciences
Celebrate With Us
Roger Smith

Roger Smith

Professor Emeritus Department of Veterinary Pathobiology
Contact
ROSMITH@cvm.tamu.edu
9798455167
TAMU Mailstop: 4467

Research and Scholarly Interests

Application of flow cytometry to study of animal disease and clinical veterinary medicine; core flow cytometry laboratory.

EDUCATION

  • B.A., Rice University, 1973
  • B.S., Texas A&M University, 1976
  • D.V.M., Texas A&M University, 1977
  • Ph.D., Baylor College of Medicine, 1984

CREDENTIALS

  • Texas Veterinary Medical License: 4191
  • Immunology
  • Chamoun-Emanuelli, AM. G Wright, R Smith III, Münch RC, Buchholz CJ, and Chen Z (2015). In vitro incorporation of a cell-binding protein to a lentiviral vector using an engineered split intein enables targeted delivery of genetic cargo BIOTECHNOL. BIOENG., 2611-2617
  • Mitchell A, Rivas KA, Smith R 3rd, Watts AE (2015). Cryopreservation of equine mesenchymal stem cells in 95% autologous serum and 5% DMSO does not alter post-thaw growth or morphology in vitro compared to fetal bovine serum or allogeneic serum at 20 or 95% and DMSO at 10 or 5% STEM CELL RESEARCH & THERAPY., 231
  • Pohlenz, C, Buentello, A , Criscitiello, MF, Mwangi, W, Smith, R III, Gatlin, DM (2012). Synergies between vaccination and dietary arginine and glutamine supplementation improve the immune response of channel catfish against Edwardsiella ictaluri FISH & SHELLFISH IMMUNOLOGY., 543-551
  • Steelman AJ, R Smith III, CJ Welsh, and J Li. (2013). Galectin-9 is Up-regulated in Astrocytes by TNF and Promotes Encephalitogenic T-cell Apoptosis. J. BIOL. CHEM. 288, 23776-23787
  • Hoose SA, MC Leitch, MM Kelly, R Smith III, and M Polymenis. (2013). Saccharomyces cerevisiae deletion strains with complex DNA content profiles. FEMS MICROBIOLOGY LETTERS. 345, 72-76
  • Steelman AJ, Dean DD, Young CR, Smith R 3rd, Prentice TW, Meagher MW, Welsh CJ (2009). Restraint stress modulates virus specific adaptive immunity during acute Theiler's virus infection. BRAIN BEHAV IMMUN. 6, 830-43
  • Stoica G, Lungu G, Martini-Stoica H, Waghela S, Levine J, Smith R 3rd (2009). Identification of cancer stem cells in dog glioblastoma. VET PATHOL. 3, 391-406
  • Chadalapaka G, Jutooru I, Chintharlapalli S, Papineni S, Smith R 3rd, Li X, Safe S (2008). Curcumin decreases specificity protein expression in bladder cancer cells. CANCER RES. 13, 5345-54
  • Vanderlaag K, Su Y, Frankel AE, Grage H, Smith R 3rd, Khan S, Safe S (2008). 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit proliferation of estrogen receptor-negative breast cancer cells by activation of multiple pathways. BREAST CANCER RES TREAT. 2, 273-83
  • Zhang S, Li X, Burghardt R, Smith R 3rd, Safe SH (2005). Role of estrogen receptor (ER) alpha in insulin-like growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells. J MOL ENDOCRINOL. 3, 433-47
  • Abdelrahim M, Smith R 3rd, Burghardt R, Safe S (2004). Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells. CANCER RES. 18, 6740-9
  • Chaffin MK, Cohen ND, Martens RJ, Edwards RF, Nevill M, Smith R 3rd (2004). Hematologic and immunophenotypic factors associated with development of Rhodococcus equi pneumonia of foals at equine breeding farms with endemic infection. VET IMMUNOL IMMUNOPATHOL. 1-2, 33-48
  • Morrow D, Qin C, Smith R 3rd, Safe S (2004). Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation. J STEROID BIOCHEM MOL BIOL. 1, 27-36
  • Abdelrahim M, Smith R 3rd, Safe S (2003). Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells. MOL PHARMACOL. 6, 1373-81
  • Qin C, Burghardt R, Smith R, Wormke M, Stewart J, Safe S (2003). Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. CANCER RES. 5, 958-64
  • Atshaves BP, Storey SM, Petrescu A, Greenberg CC, Lyuksyutova OI, Smith R 3rd, Schroeder F (2002). Expression of fatty acid binding proteins inhibits lipid accumulation and alters toxicity in L cell fibroblasts. AM J PHYSIOL CELL PHYSIOL. 3,
  • Modiano JF, Smith R 3rd, Wojcieszyn J, Thomas JS, Rosenbaum BA, Ball C, Nicholds EA, Anthony MA, Barton CL (1998). The use of cytochemistry, immunophenotyping, flow cytometry, and in vitro differentiation to determine the ontogeny of a canine monoblastic leukemia. VET CLIN PATHOL. 2, 40-49
  • Abdelrahim M, Samudio I, Smith R 3rd, Burghardt R, Safe S (2002). Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells. J BIOL CHEM. 32, 28815-22
  • Smith R 3rd, Thomas JS (2002). Quantitation of reticulated platelets in healthy dogs and in nonthrombocytopenic dogs with clinical disease. VET CLIN PATHOL. 1, 26-32
  • Botos J, Smith R 3rd, Kochevar DT (2002). Retinoblastoma function is a better indicator of cellular phenotype in cultured breast adenocarcinoma cells than retinoblastoma expression. EXP BIOL MED (MAYWOOD). 5, 354-62
  • Smith R 3rd, Chaffin MK, Cohen ND, Martens RJ (2002). Age-related changes in lymphocyte subsets of quarter horse foals. AM J VET RES. 4, 531-7
  • Tennakoon DK, Smith R, Stewart MD, Spencer TE, Nayak M, Welsh CJ (2001). Ovine IFN-tau modulates the expression of MHC antigens on murine cerebrovascular endothelial cells and inhibits replication of Theiler's virus. J INTERFERON CYTOKINE RES. 10, 785-92
  • Santos RL, Tsolis RM, Bäumler AJ, Smith R 3rd, Adams LG (2001). Salmonella enterica serovar typhimurium induces cell death in bovine monocyte-derived macrophages by early sipB-dependent and delayed sipB-independent mechanisms. INFECT IMMUN. 4, 2293-301
  • Miller S, Kennedy D, Thomson J, Han F, Smith R, Ing N, Piedrahita J, Busbee D (2000). A rapid and sensitive reporter gene that uses green fluorescent protein expression to detect chemicals with estrogenic activity. TOXICOL SCI. 1, 69-77
  • Cole DJ, Snowden K, Cohen ND, Smith R (1999). Detection of Cryptosporidium parvum in horses: thresholds of acid-fast stain, immunofluorescence assay, and flow cytometry. J CLIN MICROBIOL. 2, 457-60
  • Cole DJ, Cohen ND, Snowden K, Smith R (1998). Prevalence of and risk factors for fecal shedding of Cryptosporidium parvum oocysts in horses. J AM VET MED ASSOC. 9, 1296-302
  • Wang W, Smith R 3rd, Burghardt R, Safe SH (1997). 17 beta-Estradiol-mediated growth inhibition of MDA-MB-468 cells stably transfected with the estrogen receptor: cell cycle effects. MOL CELL ENDOCRINOL. 1, 49-62
  • Seo SH, Wang L, Smith R, Collisson EW (1997). The carboxyl-terminal 120-residue polypeptide of infectious bronchitis virus nucleocapsid induces cytotoxic T lymphocytes and protects chickens from acute infection. J VIROL. 10, 7889-94
  • Sapatino BV, Petrescu AD, Rosenbaum BA, Smith R 3rd, Piedrahita JA, Welsh CJ (1995). Characteristics of cloned cerebrovascular endothelial cells following infection with Theiler's virus. II. Persistent infection. J NEUROIMMUNOL. 2, 127-35
  • Welsh CJ, Sapatino BV, Rosenbaum BA, Smith R 3rd (1995). Characteristics of cloned cerebrovascular endothelial cells following infection with Theiler's virus. I. Acute infection. J NEUROIMMUNOL. 2, 119-25
  • Woods PR, Gossett RE, Jain NC, Smith R 3rd, Rappaport ES, Kasari TR (1993). Acute myelomonocytic leukemia in a calf. J AM VET MED ASSOC. 11, 1579-82
  • Welsh J, Sapatino B, Rosenbaum B, Smith R, Linthicum S (1993). Correlation between susceptibility to demyelination and interferon-gamma induction of major histocompatibility complex class II antigens on murine cerebrovascular endothelial cells. J NEUROIMMUNOL. 1, 91-7
  • Price RE, Templeton JW, Smith R 3rd, Adams LG (1993). Modulation of the intracellular survival of Brucella abortus by tuftsin and muramyl dipeptide. VET IMMUNOL IMMUNOPATHOL. 3, 265-79
  • Smith R 3rd, Adams LG, Sowa BA, Ficht TA (1990). Induction of lymphocyte responsiveness by the outer membrane-peptidoglycan complex of rough strains of Brucella abortus. VET IMMUNOL IMMUNOPATHOL. 1, 31-48
  • Smith R 3rd, Kapatsa JC, Sherwood SJ 3rd, Ficht TA, Templeton JW, Adams LG (1990). Differential reactivity of bovine lymphocytes to species of Brucella. AM J VET RES. 4, 518-23
  • Smith R 3rd, Kapatsa JC, Rosenbaum BA, Adams LG (1990). Bovine T-lymphocyte lines reactive with Brucella abortus. AM J VET RES. 4, 512-7
  • Price RE, Templeton JW, Smith R 3rd, Adams LG (1990). Ability of mononuclear phagocytes from cattle naturally resistant or susceptible to brucellosis to control in vitro intracellular survival of Brucella abortus. INFECT IMMUN. 4, 879-86
  • Harmon BG, Adams LG, Templeton JW, Smith R 3rd (1989). Macrophage function in mammary glands of Brucella abortus-infected cows and cows that resisted infection after inoculation of Brucella abortus. AM J VET RES. 4, 459-65
  • Shogo Mori, Howard Williams, Davey Cagle, Kristopher Karanovich, F. David Horgen, Roger Smith III, and Coran M. H. Watanabe (2015). Macrolactone Nuiapolide, Isolated from a Hawaiian Marine Cyanobacterium, Exhibits Anti-Chemotactic Activity MARINE DRUGS. 10,

ACADEMICS

DEPARTMENTS

OUTREACH

UNITS