Publications

Updated: Aug. 19, 2019
Visit PubMed listing for Sargurunathan Subashchandrabose for most up-to-date listing.

Saenkham P, Hyre AN, Hanson BS, Donati GL, Adams LG, Ryan C, Londoño A, Planet PJ and Subashchandrabose S. Copper Resistance Promotes Fitness of Methicillin-Resistant Staphylococcus aureus during Urinary Tract Infection. mBio. 2021 Oct 26;12(5):e0203821. doi: 10.1128/mBio.02038-21. 

Casanova-Hampton K, Carey A, Kassam S, Garner A, Donati GL, Thangamani S, Subashchandrabose S. A genome-wide screen reveals the involvement of enterobactin-mediated iron acquisition in Escherichia coli survival during copper stress. Metallomics. 2021 Sep 6;13(9):mfab052. doi: 10.1093/mtomcs/mfab052.

Casna BR, Simmerson SM and Subashchandrabose S. Feasibility study evaluating a veterinary point-of-care urine culture system for diagnosing septic peritonitis. Vet Emerg Crit Care. 2021 Sep;31(5):595-600. doi: 10.1111/vec.13098.Epub 2021 Jul 31.

Saenkham P, Ritter M, Donati GL, Subashchandrabose S. Copper primes adaptation of uropathogenic Escherichia coli to superoxide stress by activating superoxide dismutases. PLoS Pathog. 2020 Aug 26;16(8):e1008856. doi: 10.1371/journal.ppat.1008856.

Saenkham P, Jennings-Gee J, Hanson B, Kock ND, Adams LG, Subashchandrabose S. Hyperglucosuria induced by dapagliflozin augments bacterial colonization in the murine urinary tract. Diabetes Obes Metab. 2020 Sep;22(9):1548-1555. doi: 10.1111/dom.14064. 

 
Sintsova A, Frick-Cheng AE, Smith S, Pirani A, Subashchandrabose S, Snitkin ES, Mobley H. Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with UTIs. Elife. 2019 Oct 21;8:e49748. doi: 10.7554/eLife.49748.

Nagpal R, Wang S, Ahmadi S, Hayes J, Gagliano J, Subashchandrabose S, Kitzman DW, Becton T, Read R, Yadav H. Human-origin probiotic cocktail increases short-chain fatty acid production via modulation of mice and human gut microbiome. Sci Rep. 2018 Aug 23;8(1):12649. doi:10.1038/s41598-018-30114-4. PubMed PMID: 30139941; PubMed Central PMCID: PMC6107516.


Packiriswamy N, Gandy J, Smith SN, Mobley HLT, Sordillo LM, Subashchandrabose S. Distinct Signature of Oxylipid Mediators of Inflammation during Infection and Asymptomatic Colonization by E. coli in the Urinary Bladder. Mediators Inflamm. 2017;2017:4207928. doi:10.1155/2017/4207928. Epub 2017 Dec 27. PubMed PMID: 29445256; PubMed Central PMCID: PMC5763092.


Sintsova A, Smith S, Subashchandrabose S, Mobley HL. Role of Ethanolamine Utilization Genes in Host Colonization during Urinary Tract Infection. Infect Immun. 2018 Feb 20;86(3). pii: e00542-17. doi:10.1128/IAI.00542-17. Print 2018 Mar. PubMed PMID: 29229730; PubMed Central PMCID: PMC5820945.


Hyre AN, Kavanagh K, Kock ND, Donati GL, Subashchandrabose S. Copper Is a Host Effector Mobilized to Urine during Urinary Tract Infection to Impair Bacterial Colonization. Infect Immun. 2017 Feb 23;85(3). pii: e01041-16. doi:10.1128/IAI.01041-16. Print 2017 Mar. PubMed PMID: 28031261; PubMed Central PMCID: PMC5328488.


Subashchandrabose S, Smith S, DeOrnellas V, Crepin S, Kole M, Zahdeh C, Mobley HL. Acinetobacter baumannii Genes Required for Bacterial Survival during Bloodstream Infection. mSphere. 2015 Nov 4;1(1). pii: e00013-15. doi:10.1128/mSphere.00013-15. eCollection 2016 Jan-Feb. PubMed PMID: 27303682; PubMed Central PMCID: PMC4863628.


Subashchandrabose S, Mobley HLT. Virulence and Fitness Determinants of Uropathogenic Escherichia coli. Microbiol Spectr. 2015 Aug;3(4). doi:10.1128/microbiolspec.UTI-0015-2012. Review. PubMed PMID: 26350328; PubMed Central PMCID: PMC4566162.


Subashchandrabose S, Mobley HL. Back to the metal age: battle for metals at the host-pathogen interface during urinary tract infection. Metallomics. 2015 Jun;7(6):935-42. doi:10.1039/c4mt00329b. Review. PubMed PMID: 25677827; PubMed Central PMCID: PMC4634365.


Brumbaugh AR, Smith SN, Subashchandrabose S, Himpsl SD, Hazen TH, Rasko DA, Mobley HL. Blocking yersiniabactin import attenuates extraintestinal pathogenic Escherichia coli in cystitis and pyelonephritis and represents a novel target to prevent urinary tract infection. Infect Immun. 2015 Apr;83(4):1443-50. doi:10.1128/IAI.02904-14. Epub 2015 Jan 26. PubMed PMID: 25624354; PubMed Central PMCID: PMC4363403.


Subashchandrabose S, Hazen TH, Brumbaugh AR, Himpsl SD, Smith SN, Ernst RD, Rasko DA, Mobley HL. Host-specific induction of Escherichia coli fitness genes during human urinary tract infection. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18327-32. doi:10.1073/pnas.1415959112. Epub 2014 Dec 8. PubMed PMID:  25489107; PubMed Central PMCID: PMC4280598.


Subashchandrabose S, Smith SN, Spurbeck RR, Kole MM, Mobley HL. Genome-wide detection of fitness genes in uropathogenic Escherichia coli during systemic infection. PLoS Pathog. 2013;9(12):e1003788. doi:10.1371/journal.ppat.1003788. Epub 2013 Dec 5. PubMed PMID: 24339777; PubMed Central PMCID: PMC3855560.


Subashchandrabose S, Hazen TH, Rasko DA, Mobley HL. Draft genome sequences of five recent human uropathogenic Escherichia coli isolates. Pathog Dis. 2013 Oct;69(1):66-70. Epub 2013 Oct 1. PubMed PMID: 23821517; PubMed Central PMCID: PMC3843978.


Subashchandrabose S, Leveque RM, Kirkwood RN, Kiupel M, Mulks MH. The RNA chaperone Hfq promotes fitness of Actinobacillus pleuropneumoniae during porcine pleuropneumonia. Infect Immun. 2013 Aug;81(8):2952-61. doi: 10.1128/IAI.00392-13. Epub 2013 Jun 3. PubMed PMID: 23732171; PubMed Central PMCID: PMC3719588.


Subashchandrabose S, LeVeque RM, Wagner TK, Kirkwood RN, Kiupel M, Mulks MH. Branched-chain amino acids are required for the survival and virulence of Actinobacillus pleuropneumoniae in swine. Infect Immun. 2009 Nov;77(11):4925-33. doi:10.1128/IAI.00671-09. Epub 2009 Aug 24. PubMed PMID: 19703979; PubMed Central PMCID: PMC2772520.