Publications

various images in publications


BOOK CHAPTERS


2023

Immune Response in Mice

Arenas-Gamboa AM. Brucella. In: Pathogenesis of Bacterial Infections in Animals. (ed. J. F. Prescott), 5th ed., John Wiley & Sons, Inc., Hoboken, NJ, pp. 361-372.

 

 


PEER-REVIEWED JOURNAL ARTICLES


2023

Immune Response in Mice

52. Laine CG, Johnson VE, Scott HM, Arenas-Gamboa AM. Global Estimate of Human Brucellosis Incidence. Emerg Infect Dis. 29(9), 1789-1797, 2023; doi.org/10.3201/eid2909.230052.

 


2022

Immune Response in Mice

51. Stranahan LW, Garcia-Gonzalez DG, Hensel ME, Arenas-Gamboa AM. Primary and memory immune responses against rough Brucella canis are less robust compared to smooth B. abortus and B. melitensis following intratracheal infection in mice. Front Immunol. Sec. Microbial Immunology. August 11, 2022; doi.org/10.3389/fimmu.2022.959328.

 

Human Brucellosis

50. Laine CG, Scott HM, and Arenas-Gamboa AM. Human brucellosis: Widespread information deficiency hinders an understanding of global disease frequency. PLoS Negl Trop Dis. May 17, 2022; doi:10.1371/journal.pntd.0010404.

 


2021

When the going gets rough

49. Stranahan LW and Arenas-Gamboa AM. When the Going Gets Rough: The Significance of Brucella Lipopolysaccharide Phenotype in Host–Pathogen Interactions. Front. Microbiol.. July 15, 2021; doi:10.3389/fmicb.2021.713157.

 

AgSecure Program

48. Arenas-Gamboa AM, Simmons HL, Krecek RC, Logan LL, Ellis D, Ptaschinski M, Cargill J, Werre S, Mulumba M, Heath L. AgSecure Africa Programme™: A Sustainable Training Approach for Africa. JVDI. Jan 25, 2021; doi:10.3138/jvme-2020-0047.

 

Characterization of Lesions

47. Camargo-Castañeda AM, Stranahan LW, Edwards JF, Garcia-Gonzalez DG, Roa L, Ávila-Granados LM, Hensel ME, Arenas-Gamboa AM. Characterization of epididymal and testicular histologic lesions and use of immunohistochemistry and PCR on formalin-fixed tissues to detect Brucella canis in male dogs. JVDI. 39:617-625. Jan 19, 2021; doi:10.1177/1040638720986883

 

Evaluation of the safety profile

46. Castaño-Zubieta MR, Rossetti CA, García-González DG, Maurizio E, Hensel ME, Rice-Ficht AC, Ficht TA, Arenas-Gamboa AM. Evaluation of the safety profile of the vaccine candidate Brucella melitensis 16MΔvjbR strain in goats. Vaccine. Jan 15, 2021; doi:10.1016/j.vaccine.2020.11.033.

 

Porcine Babesiosis

45. Avenant A, Park JY, Vorster I, Mitchell EP, Arenas-Gamboa AM. Porcine babesiosis caused by Babesia sp. Suis in a pot-bellied pig in South Africa. Front. Vet. Sci. 7:620462. Jan 6, 2021; doi: 10.3389/fvets.2020.620462.

 

 


2020

Scoping Review of Brucellosis in Cameroon

44. Laine CG, Wade A, Scott HM, Krecek RC, Arenas-Gamboa AM. Scoping Review of Brucellosis in Cameroon: Where do we stand, and where are we going? PLoS One. 15(9):e0239854. Sep 28, 2020; doi: 10.1371/journal.pone.0239854

 

Brucella abortus and Pregnancy in Mice
43. Adetunji SA, Faustman DL, Adams LG, Garcia-Gonzalez DG, Hensel ME, Khalaf OH, Arenas-Gamboa AM. Brucella abortus and Pregnancy in Mice: Impact of Chronic Infection on Fertility and the Role of Regulatory T Cells in Tissue Colonization. Infect Immun. 88(10)e00257-20. Sep 18, 2020; doi: 10.1128/IAI.00257-20.

 

Evaluation of the efficacy of a vaccine candidate
42. Hensel ME, Chaki SP, Stranahan L, Gregory AE, van Schaik EJ, Garcia-Gonzalez DG, Khalaf OH, Samuel JE, Arenas-Gamboa AM. Intratracheal inoculation with Brucella melitensis in the pregnant guinea pig is an improved model for reproductive pathogenesis and vaccine studies. Infect Immun. Jul 2020, doi: 10.1128/IAI.00204-20

 

 

Evaluation of the efficacy of a vaccine candidate

41. Nejad RB, Krecek RC, Khalaf OH, Hailat N, Arenas-Gamboa AM. Brucellosis in the Middle East: Current Situation and a Pathway Forward. PLoS Negl Trop Dis. 2020;14(5):e0008071. doi:10.1371/journal.pntd.0008071

 

 

Evaluation of the efficacy of a vaccine candidate

40. Stranahan LW, Chaki SP, Garcia-Gonzalez DG, Khalaf OH, Arenas-Gamboa AM. Evaluation of the Efficacy of the Brucella canis RM6/66 Δ vjbR Vaccine Candidate for Protection against B. canis Infection in Mice. mSphere. May/June 2020. 5(3). doi: 10.1128/mSphere.00172-20

 

 

Vaccine Candidate Brucella melitensis paper

39. Hensel ME, Garcia-Gonzalez DG, Chaki SP, Hartwig A, Gordy PW, Bowen R, Ficht TA, Arenas-Gamboa AM. Vaccine Candidate Brucella melitensis 16MΔvjbR Is Safe in a Pregnant Sheep Model and Confers Protection. mSphere. May 2020, 5(3) e00120-20. doi: 10.1128/mSphere.00120-20

 

 

Immersion Foot Syndrome paper

38. Taylor BM, Chaffin MK, Rodrigues-Hoffmann A, Edwards JF, Arenas-Gamboa AM. Immersion Foot Syndrome in 6 Equids Exposed to Hurricane Floodwaters. Vet Pathol. Mar;57(2):290-295. doi: 10.1177/0300985819900019

 

 

Bench to Shop Program

37. Arenas-Gamboa AM, Simmons HL, Werre SR, Krecek RC. Bench to Shop™: An Interdisciplinary Training Program for Transitioning of Transboundary Animal Disease Research to Commercialization. [published online ahead of print, 2020 Mar 12]. JVME. doi:10.3138/jvme.2019-0048.

 
 

Building the Evidence Base for the Prevention of Raw Milk-Acquired Brucellosis

36. Adetunji SA, Ramirez G, Rice-Ficht A, Perez L, Foster MJ, Arenas-Gamboa AM. Building the Evidence Base for the Prevention of Raw Milk-Acquired Brucellosis: A Systematic Review. Front. Public Health. 8:76. doi: 10.3389/fpubh.2020.00076.

 

 

Interaction of Brucella abortus with osteoclasts

35. Khalaf OH, Chaki SP, Garcia-Gonzalez DG, Suva LJ, Gaddy D, Arenas-Gamboa AM. Interaction of Brucella abortus with Osteoclasts: a Step toward Understanding Osteoarticular Brucellosis and Vaccine Safety [published online ahead of print, 2020 Jan 13]. Infect Immun. doi:10.1128/IAI.00822-19.

 

 


2019

Brucellosis in Colombia

34. Avila-Granados LM, Garcia-Gonzalez DG, Zambrano-Varon JL, Arenas-Gamboa AM. Brucellosis in Colombia: Current Status and Challenges in the Control of an Endemic Disease. Front Vet Sci. 2019;6:321. Published 2019 Sep 24. doi:10.3389/fvets.2019.00321

 

 

Vaccine-safety-studies

33. Zriba S, Garcia-Gonzalez DG, Khalaf OH, Wheeler L, Chaki SP, Rice-Ficht Allison, Ficht TA, Arenas-Gamboa AM. Vaccine safety studies of Brucella abortus S19 and S19ΔvjbR in pregnant swine. Vaccine X. 2019; 3:100041. Published 2019 Aug 22. doi:10.1016/j.jvacx.2019.100041

 

Vaccine-safety-studies

32. Stranahan LW, Khalaf OH, Garcia-Gonzalez DG, Arenas-Gamboa AM. Characterization of Brucella canis infection in mice. PLoS One. 2019;14(6):e0218809. Published 2019 Jun 20. doi:10.1371/journal.pone.0218809

 

The NOD-scid IL2rγnull Mouse Model

31. Khalaf OH, Chaki SP, Garcia-Gonzalez DG, Ficht TA, Arenas-Gamboa AM. The NOD-scid IL2rγnull Mouse Model Is Suitable for the Study of Osteoarticular Brucellosis and Vaccine Safety. Infect Immun. 2019;87(6):e00901-18. Published 2019 May 21. doi:10.1128/IAI.00901-18

 

 

Characterization of an intratracheal aerosol challenge model

30. Hensel ME, Garcia-Gonzalez DG, Chaki SP, Samuel J, Arenas-Gamboa AM. Characterization of an intratracheal aerosol challenge model of Brucella melitensis in guinea pigs [published correction appears in PLoS One. 2019 Jun 11;14(6):e0218065]. PLoS One. 2019;14(3):e0212457. Mar 5, 2019; doi:10.1371/journal.pone.0212457
Click here for the erratum for Figure 3.

A systematic review and meta-analysis

29. Adetunji SA, Ramirez G, Foster MJ, Arenas-Gamboa AM. A systematic review and meta-analysis of the prevalence of osteoarticular brucellosis. PLoS Negl Trop Dis. 2019;13(1):e0007112. Jan 18, 2020; doi:10.1371/journal.pntd.0007112


2018

A Neglected Animal Model

28. Hensel ME, Arenas-Gamboa AM. A Neglected Animal Model for a Neglected Disease: Guinea Pigs and the Search for an Improved Animal Model for Human Brucellosis. Front Microbiol. 2018;9:2593. Published 2018 Oct 31. doi:10.3389/fmicb.2018.02593

 

 

Brucellosis in Dogs

27. Hensel ME, Negron M, Arenas-Gamboa AM. Brucellosis in Dogs and Public Health Risk. Emerg Infect Dis. 2018;24(8):1401–1406. doi:10.3201/eid2408.171171

 

 

German Shepherd Dog with vomiting, retching and tachypnoea

26. Parambeth JC, Simpler R, Ruoff C, Spaulding K, Bryan L, Arenas-Gamboa A, Clark BE, Eichelberger B. German Shepherd Dog with vomiting, retching and tachypnoea. Aust Vet Pract. 2018; 48 (1):25-26.

 

 
 

Melanoma

25. Adetunji SA, Krecek RC, O’Dell N, Prozesky L, Steyl J, Arenas-Gamboa AM. MELANOMA IN GOLDEN AND KING WILDEBEESTS ( CONNOCHAETES TAURINUS). J Zoo Wildl Med. 2018;49(1):134–142. doi:10.1638/2017-0059R1.1

 

 

Brucellosis remains a neglected disease

24. Franc KA, Krecek RC, Häsler BN, Arenas-Gamboa AM. Brucellosis remains a neglected disease in the developing world: a call for interdisciplinary action. BMC Public Health. 2018;18(1):125. Published 2018 Jan 11. doi:10.1186/s12889-017-5016-y

 

 


2017

Caprine_Brucellosis

23. Rossetti CA, Arenas-Gamboa AM, Maurizio E. Caprine brucellosis: A historically neglected disease with significant impact on public health. PLoS Negl Trop Dis. 2017;11(8):e0005692. Published 2017 Aug 17. doi:10.1371/journal.pntd.0005692

 

 

Identification of Brucella spp

22. Pedersen K, Bauer NE, Olsen S, Arenas-Gamboa AM, Henry AC, Sibley TD, Gidlewski T. Identification of Brucella spp. in feral swine (Sus scrofa) at abattoirs in Texas, USA. Zoonoses Public Health. 2017;64(8):647–654. doi:10.1111/zph.12359

 

 

Global Reprogramming of Host Kinase Signaling

21. Pandey A, Ding SL, Qin QM, Gupta R, Gomez G, Lin F, Feng X, Fachini da Costa L, Chaki SP, Katepalli M, Case ED, van Schaik EJ, Sidiq T, Khalaf O, Arenas A, Kobayashi KS, Samuel JE, Rivera GM, Alaniz RC, Sze SH, Qian X, Brown WJ, Rice-Ficht A, Russell WK, Ficht TA, de Figueiredo P. Global Reprogramming of Host Kinase Signaling in Response to Fungal Infection. Cell Host Microbe. 2017;21(5):637–649.e6. doi:10.1016/j.chom.2017.04.008

 

 


2016

Human Brucellosis and Adverse Pregnancy Outcomes

20. Arenas-Gamboa AM, Rossetti CA, Chaki SP, Garcia-Gonzalez DG, Adams LG, Ficht TA. Human Brucellosis and Adverse Pregnancy Outcomes. Curr Trop Med Rep. 2016;3(4):164–172. doi:10.1007/s40475-016-0092-0

 

 

The Case for Live Attenuated Vaccines

19. Pandey A, Cabello A, Akoolo L, Rice-Ficht A, Arenas-Gamboa AM, McMurray D, Ficht TA; de Figueiredo P. The Case for Live Attenuated Vaccines against the Neglected Zoonotic Diseases Brucellosis and Bovine Tuberculosis. PLoS Negl Trop Dis. 2016;10(8):e0004572. Published 2016 Aug 18. doi:10.1371/journal.pntd.0004572

 

 

Reticulo-ruminal milk accumulation

18. Adetunji SA, Gomez G, De la Concha-Bermejillo A, Oliveira F, Arenas-Gamboa AM. Reticulo-ruminal milk accumulation (ruminal drinking) in five pre-ruminant white-tailed deer (Odocoileus virginianus) in Texas. Braz J Vet Pathol. 2016; 9(2):47-54.

 

 

Seropositivity and risk factors for Brucella

17. Geresu MA, Ameni G, Kassa T, Tuli G, Arenas A, Kassa GM. Seropositivity and risk factors for Brucella in dairy cows in Asella and Bishoftu towns, Oromia Regional State, Ethiopia. Afr J Microbiol Res. 2016; 10(7):203-213. doi:10.5897/AJMR2015.7707

 

 

Isolation and identification of Brucella species from dairy cattle

16. Geresu MA, Ameni G, Wubete A, Arenas-Gamboa AM, Kassa GM. Isolation and identification of Brucella species from dairy cattle by biochemical tests: The first report from Ethiopia. World Vet J. 2016; 6(2):80-88.

 

 


2015

Materials composed of the Drosophila Hox protein

15. Patterson JL, Arenas-Gamboa AM, Wang TY, Hsiao HC, Howell DW, Pellois JP, Rice-Ficht A, Bondos SE. Materials composed of the Drosophila Hox protein Ultrabithorax are biocompatible and nonimmunogenic. J Biomed Mater Res A. 2015;103(4):1546–1553. doi:10.1002/jbm.a.35295

 

 


2014

Peripheral neuroblastomas in dogs

14. Arenas-Gamboa AM, Tanabe M, Edwards J, Storts R. Peripheral Neuroblastomas in Dogs: A Case Series. J Comp Pathol. 2014;150(4):361–365. doi:10.1016/j.jcpa.2013.11.211

 

 


2013

Aerosol-induced brucellosis increases TLR-2 expression

13. Lee KM, Chiu KB, Sansing HA, Didier DJ, Ficht TA, Arenas-Gamboa AM, Roy, CJ, MacLean AG. Aerosol-induced brucellosis increases TLR-2 expression and increased complexity in the microanatomy of astroglia in rhesus macaques. Front Cell Infect Microbiol. 2013;3:86. Published 2013 Dec 2. doi:10.3389/fcimb.2013.00086

 

 


2012

Extended safety and efficacy studies

12. Arenas-Gamboa AM, Rice-Ficht AC, Fan Y, Kahl-McDonagh MM, Ficht TA. Extended Safety and Efficacy Studies of the Attenuated Brucella Vaccine Candidates 16M∆vjbR and S19∆vjbR in the Immunocompromised IRF-1¯/¯ Mouse Model. Clin Vaccine Immunol. 2012;19(2):249–260. doi:10.1128/CVI.05321-11

 

 

Sclerosing cholangitis in baboons

11. Arenas-Gamboa AM, Bearss JJ, Hubbard GB, Porter BF, Owston MA, Dick Jr. EJ. Sclerosing Cholangitis in Baboons (Papio spp) Resembling Primary Sclerosing Cholangitis of Humans. Vet Pathol. 2012;49(3):524–527. doi:10.1177/0300985811419532

 

 


2011

Protective efficacy and safety of Brucella melitensis 16MΔmucR

10. Arenas-Gamboa AM, Rice-Ficht AC, Kahl-McDonagh MM, Ficht TA. Protective Efficacy and Safety of Brucella melitensis 16M∆mucR against Intraperitoneal and Aerosol Challenge in BALB/c Mice [published correction appears in Infect Immun. 2011 Dec;79(12):5040]. Infect Immun. 2011;79(9):3653–3658. doi:10.1128/IAI.05330-11

 

 

Fibrous band associated with the non-coronary aortic valve cusp in a dog

9. Ajithdoss DK, Arenas-Gamboa AM, Edwards JF. A fibrous band associated with the non-coronary aortic valve cusp in a dog. J Vet Cardiol. 2011;13(2):127–129. doi:10.1016/j.jvc.2011.01.004

 

 

Epithelioid Haemangiosarcoma

8. Arenas-Gamboa AM, Mansell J. Epithelioid Haemangiosarcoma in the Ocular Tissue of Horses. J Comp Pathol. 2011;144(4):328–333. doi:10.1016/j.jcpa.2010.10.011

 

 


2010

Polymeric particles in vaccine delivery

7. Rice-Ficht AC, Arenas-Gamboa AM, Kahl-McDonagh MM, Ficht TA. Polymeric particles in vaccine delivery. Curr Opin Microbiol. 2010;13(1):106–112. doi:10.1016/j.mib.2009.12.001

 

 


2009

Oral Vaccination confers protection

6. Arenas-Gamboa AM, Ficht TA, Davis DS, Elzer PH, Kahl-McDonagh M, Wong-Gonzalez A, Rice-Ficht AC. ORAL VACCINATION WITH MICROENCAPSULED STRAIN 19 VACCINE CONFERS ENHANCED PROTECTION AGAINST BRUCELLA ABORTUS STRAIN 2308 CHALLENGE IN RED DEER (CERVUS ELAPHUS ELAPHUS). J Wildl Dis. 2009;45(4):1021–1029. doi:10.7589/0090-3558-45.4.1021

 

 

Brucellosis: the case for live, attenuated vaccines

5. Ficht TA, Kahl-McDonagh MM, Arenas-Gamboa AM, Rice-Ficht AC. Brucellosis: the case for live, attenuated vaccines. Vaccine. 2009;27 Suppl 4(Suppl 4):D40–D43. doi:10.1016/j.vaccine.2009.08.058

 

 

 

 

Enhanced immune response of red deer

4. Arenas-Gamboa AM, Ficht TA, Davis DS, Elzer PH, Wong-Gonzalez A, Rice-Ficht AC. ENHANCED IMMUNE RESPONSE OF RED DEER (CERVUS ELAPHUS) TO LIVE RB51 VACCINE STRAIN USING COMPOSITE MICROSPHERES. J Wildl Dis. 2009;45(1):165–173. doi:10.7589/0090-3558-45.1.165

 

 

The Brucella abortus S19 DeltavjbR live vaccine candidate

3. Arenas-Gamboa AM, Ficht TA, Kahl-McDonagh MM, Gomez G, Rice-Ficht AC. The Brucella abortus S19 ΔvjbR Live Vaccine Candidate Is Safer than S19 and Confers Protection against Wild-type Challenge in BALB/c Mice When Delivered in a Sustained-Release Vehicle. Infect Immun. 2009;77(2):877–884. doi:10.1128/IAI.01017-08

 

 


2008

Immunization with a single dose of a microencapsulated Brucella melitensis mutant

2. Arenas-Gamboa AM, Ficht TA, Kahl-McDonagh MM, Rice-Ficht AC. Immunization with a Single Dose of a Microencapsulated Brucella melitensis Mutant Enhances Protection against Wild-Type Challenge. Infect Immun. 2008;76(6):2448–2455. doi:10.1128/IAI.00767-07

 

 


2007

Aerosol infection of BALB/c mice

1. Kahl-McDonagh MM, Arenas-Gamboa AM, Ficht TA. Aerosol Infection of BALB/c Mice with Brucella melitensis and Brucella abortus and Protective Efficacy against Aerosol Challenge. Infect Immun. 2007;75(10):4923–4932. doi:10.1128/IAI.00451-07