The Wiener lab focuses on the development of a 3D model to study skin diseases in dogs and cats, aiming to reduce the need for live animal experimentation. The use of skin organoids recreates the 3D skin architecture and it is being used to study atopic dermatitis in dogs. Currently, the lab is also establishing a skin organoid protocol for feline skin. In the future, the feline skin organoids will be used to study feline dermatophytosis (ringworm infection).
Publications
Characterization of canine epidermal organoid cultures by immunohistochemical analysis and quantitative PCR – https://doi.org/10.1111/vde.12914
Establishment and characterization of a canine keratinocyte organoid culture system – https://doi.org/10.1111/vde.12541